Search Results

Oncostatin M can sensitize sensory neurons in inflammatory pruritus.

• Authors : Tseng, Pang-Yen; Hoon, Mark A.

Subjects: ONCOSTATIN M; ITCHING; SENSORY neurons

• Source: Science Translational Medicine; 11/10/2021, Vol. 13 Issue 619, p1-11, 11p

Record details

Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses.

• Authors : Topolewski, Piotr; Zakrzewska, Karolina E.; Walczak, Jarosław

Subjects: ONCOSTATIN M; PHENOTYPIC plasticity; HETEROGENEITY

• Source: Science Signaling; 2/15/2022, Vol. 15 Issue 721, p1-9, 9p

Record details

Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.

• Authors : Headland, Sarah E.; Dengler, Hart S.; Xu, Daqi

• Source: Science Translational Medicine; 1/12/2022, Vol. 14 Issue 627, p1-15, 15p

Record details

The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination.

• Authors : Gharibani, Payam; Abramson, Efrat; Shanmukha, Shruthi

Subjects: PROTEIN kinase C; NEUROLOGICAL disorders; CENTRAL nervous system

• Source: Science Translational Medicine; 1/8/2025, Vol. 17 Issue 780, p1-13, 13p

Record details

An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup.

• Authors : Gower, Mark; Li, Ximing; Aguilar-Navarro, Alicia G.

Subjects: T cell receptors; CHILD patients; LYMPHOBLASTIC leukemia

• Source: Science Translational Medicine; 1/1/2025, Vol. 17 Issue 779, p1-16, 16p

Record details

A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis.

• Authors : Bohnacker, Sina; Henkel, Fiona D. R.; Hartung, Franziska

Subjects: GLUTAMATE dehydrogenase; T helper cells; INDOLEAMINE 2,3-dioxygenase

• Source: Science Immunology; 2024, Vol. 9 Issue 102, p1-24, 24p

Record details

Promiscuous Janus kinase binding to cytokine receptors modulates signaling efficiencies and contributes to cytokine pleiotropy.

• Authors : Zoler, Eyal; Meyer, Thomas; Bellón, Junel Sotolongo

Subjects: CYTOKINE receptors; TYPE I interferons; JANUS kinases

• Source: Science Signaling; 11/19/2024, Vol. 17 Issue 863, p1-18, 18p

Record details

Clinical, mechanistic, and therapeutic landscape of cutaneous fibrosis.

• Authors : Li, Dayan J.; Berry, Charlotte E.; Wan, Derrick C.

Subjects: FIBROSIS; FIBROBLASTS; SCARS

• Source: Science Translational Medicine; 9/25/2024, Vol. 16 Issue 766, p1-17, 17p

Record details

MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles.

• Authors : Kammann, Tobias; Cai, Curtis; Sekine, Takuya

Subjects: LYMPHOID tissue; T cells; MUCOUS membranes

• Source: Science Immunology; 2024, Vol. 9 Issue 99, p1-15, 15p

Record details

Human iPSC–liver organoid transplantation reduces fibrosis through immunomodulation.

• Authors : Tadokoro, Tomomi; Murata, Soichiro; Kato, Mimoko

Subjects: INDUCED pluripotent stem cells; HEPATIC fibrosis; BILE ducts

• Source: Science Translational Medicine; 7/24/2024, Vol. 16 Issue 757, p1-12, 12p

Record details