Search Results

Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis.

• Authors : Xie, Yingda L.; de Jager, Veronique R.; Chen, Ray Y.

Subjects: DRUG monitoring; COMPUTED tomography; TREATMENT effectiveness

• Source: Science Translational Medicine; 2/3/2021, Vol. 13 Issue 579, p1-10, 10p

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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.

• Authors : Chrysostomou, Stelios; Roy, Rajat; Prischi, Filippo

Subjects: LUNG cancer; BLADDER cancer; METASTASIS

• Source: Science Translational Medicine; 7/14/2021, Vol. 13 Issue 602, p1-16, 16p

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Commensal antimicrobial resistance mediates microbiome resilience to antibiotic disruption.

• Authors : Bhattarai, Shakti K.; Du, Muxue; Zeamer, Abigail L.

Subjects: DRUG resistance in microorganisms; MULTIDRUG-resistant tuberculosis; MYCOBACTERIUM tuberculosis

• Source: Science Translational Medicine; 1/17/2024, Vol. 16 Issue 730, p1-14, 14p

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Simultaneous control of infection and inflammation with keratin-derived antibacterial peptides targeting TLRs and co-receptors.

• Authors : Sun, Yan; Chan, Jonathan; Bose, Karthikeyan

Subjects: CELL receptors; KERATIN; PEPTIDE antibiotics

• Source: Science Translational Medicine; 3/8/2023, Vol. 15 Issue 686, p1-16, 16p

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A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.

• Authors : Blaskovich, Mark A. T.; Hansford, Karl A.; Butler, Mark S.

Subjects: ANTIBIOTICS; GRAM-positive bacterial infections; GLYCOPEPTIDE antibioticsUNITED States

• Source: Science Translational Medicine; 9/14/2022, Vol. 14 Issue 662, p1-16, 16p

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Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague.

• Authors : Jakielaszek, Charles; Hossain, Mohammad; Qian, Lian

Subjects: ORGAN culture; YERSINIA pestis; CERCOPITHECUS aethiopsUNITED States. Food & Drug Administration

• Source: Science Translational Medicine; Jun2022, Vol. 14 Issue 647, p1-14, 14p

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The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.

• Authors : Flipo, Marion; Frita, Rosangela; Bourotte, Marilyne

Subjects: MYCOBACTERIUM tuberculosis; MYCOBACTERIAL diseases; LABORATORY mice

• Source: Science Translational Medicine; 5/4/2022, Vol. 14 Issue 643, p1-14, 14p

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Shortened treatment for TB.

• Source: Science; 10/30/2020, Vol. 370 Issue 6516, p509-510, 2p

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Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria.

• Authors : Zhao, Xian-liang; Chen, Zhuang-gui; Yang, Tian-ci

Subjects: ANTIBIOTICS; ACINETOBACTER baumannii; GLUTAMINE

• Source: Science Translational Medicine; 12/22/2021, Vol. 13 Issue 625, p1-15, 15p

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Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant–associated infections.

• Authors : Gordon, Oren; Lee, Donald E.; Liu, Bessie

Subjects: RIFAMPIN; POSITRON emission tomography; LABORATORY mice

• Source: Science Translational Medicine; 12/1/2021, Vol. 13 Issue 622, p1-12, 12p

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