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Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.

• Authors : Karuppagounder SS; Sperling Center for Hemorrhagic Stroke Recovery, Burke Medical Research Institute, White Plains, NY 10605, USA. Feil Family Brain and Mind Research Institute, Weill Medical College of Cornell University, New York, NY 10065, USA.; Alim I

Subjects: Molecular Targeted Therapy*; Activating Transcription Factor 4/Activating Transcription Factor 4/Activating Transcription Factor 4/*metabolism ; Brain/Brain/Brain/*pathology

• Source: Science translational medicine [Sci Transl Med] 2016 Mar 02; Vol. 8 (328), pp. 328ra29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Education Full Text (H.W. Wilson)

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Fortifying the BBB: Border control by increasing regulators.

• Authors : Choi HA; Department of Neurosurgery and Neurology, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX 77030, USA. Email: .

Subjects: Brain Ischemia* ; Stroke*; Blood-Brain Barrier

• Source: Science translational medicine [Sci Transl Med] 2017 Jun 28; Vol. 9 (396).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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