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Academic Journal

Sterile production of interferons in the thymus affects T cell repertoire selection.

  • Authors : Ashby KM; Center for Immunology, Department of Lab Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.; Vobořil M

Subjects: Thymus Gland*/Thymus Gland*/Thymus Gland*/immunology ; Interferons*/Interferons*/Interferons*/immunology ; Mice, Inbred C57BL*

  • Source: Science immunology [Sci Immunol] 2024 Jul 26; Vol. 9 (97), pp. eadp1139. Date of Electronic Publication: 2024 Jul 26.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication

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Academic Journal

KAT2A and KAT2B prevent double-stranded RNA accumulation and interferon signaling to maintain intestinal stem cell renewal.

  • Authors : Nguyen MU; Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.; Iqbal J

Subjects: Signal Transduction* ; RNA, Double-Stranded*/RNA, Double-Stranded*/RNA, Double-Stranded*/metabolism ; Stem Cells*/Stem Cells*/Stem Cells*/metabolism

  • Source: Science advances [Sci Adv] 2024 Aug 09; Vol. 10 (32), pp. eadl1584. Date of Electronic Publication: 2024 Aug 07.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Interferon with ovarian cancer.

  • Authors : Baek AE; Science Signaling, AAAS, Washington, DC 20005, USA. Email: .

Subjects: Interferons* ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy; Animals

  • Source: Science signaling [Sci Signal] 2023 Aug 29; Vol. 16 (800), pp. eadk4659. Date of Electronic Publication: 2023 Aug 29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Academic Journal

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection.

  • Authors : Major J; Immunoregulation Laboratory, The Francis Crick Institute, London, UK.; Crotta S

Subjects: Alveolar Epithelial Cells/Alveolar Epithelial Cells/Alveolar Epithelial Cells/*pathology ; Cytokines/Cytokines/Cytokines/*metabolism ; Interferon Type I/Interferon Type I/Interferon Type I/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2020 Aug 07; Vol. 369 (6504), pp. 712-717. Date of Electronic Publication: 2020 Jun 11.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Type III interferons disrupt the lung epithelial barrier upon viral recognition.

  • Authors : Broggi A; Harvard Medical School, Boston Children's Hospital, Division of Immunology, Boston, MA, USA.; Ghosh S

Subjects: Betacoronavirus*; Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*immunology ; Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2020 Aug 07; Vol. 369 (6504), pp. 706-712. Date of Electronic Publication: 2020 Jun 11.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.

  • Authors : Licht-Murava A; Appel Alzheimer's Disease Research Institute, Weill Cornell Medicine, New York, NY, USA.; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.

Subjects: Interferons*/Interferons*/Interferons*/metabolism ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/metabolism; Mice

  • Source: Science advances [Sci Adv] 2023 Apr 21; Vol. 9 (16), pp. eade1282. Date of Electronic Publication: 2023 Apr 19.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Stress signaling boosts interferon-induced gene transcription in macrophages.

  • Authors : Boccuni L; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna 1030, Austria.

Subjects: Interferons*/Interferons*/Interferons*/genetics ; Interferons*/Interferons*/Interferons*/pharmacology ; Interferons*/Interferons*/Interferons*/metabolism

  • Source: Science signaling [Sci Signal] 2022 Dec 13; Vol. 15 (764), pp. eabq5389. Date of Electronic Publication: 2022 Dec 13.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Academic Journal

Rewiring the logic board of IFN signaling.

  • Authors : MacMicking JD; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.

Subjects: Interferons* ; Signal Transduction*; p38 Mitogen-Activated Protein Kinases

  • Source: Science signaling [Sci Signal] 2022 Dec 13; Vol. 15 (764), pp. eadf0778. Date of Electronic Publication: 2022 Dec 13.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Periodical

Can interferons stop COVID-19 before it takes hold?

Subjects: Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*prevention & control ; Interferons/Interferons/Interferons/*therapeutic use ; Pandemics/Pandemics/Pandemics/*prevention & control

  • Source: Science (New York, N.Y.) [Science] 2020 Jul 10; Vol. 369 (6500), pp. 125-126.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer.

  • Authors : Hubert M; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, 69008, France.; Laboratoire d'Immunothérapie des Cancers de Lyon (LICL), Lyon, France.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*immunology ; Dendritic Cells/Dendritic Cells/Dendritic Cells/*immunology ; Interferons/Interferons/Interferons/*biosynthesis

  • Source: Science immunology [Sci Immunol] 2020 Apr 17; Vol. 5 (46). Date of Electronic Publication: 2020 Apr 17.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication

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