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Academic Journal

ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress.

  • Authors : Xu X; Division of Gastroenterology and Hepatology, Joan & Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.; Division of Surgical Sciences, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

Subjects: Thermogenesis*/Thermogenesis*/Thermogenesis*/genetics ; Lipogenesis* ; Glycolysis*

  • Source: Science signaling [Sci Signal] 2024 Dec 03; Vol. 17 (865), pp. eadk7971. Date of Electronic Publication: 2024 Dec 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Academic Journal

Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis.

  • Authors : Khanal S; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.; Liu Y

Subjects: Glycolysis* ; Liver Cirrhosis*/Liver Cirrhosis*/Liver Cirrhosis*/metabolism ; Liver Cirrhosis*/Liver Cirrhosis*/Liver Cirrhosis*/pathology

  • Source: Science advances [Sci Adv] 2024 Jun 28; Vol. 10 (26), pp. eadn5228. Date of Electronic Publication: 2024 Jun 28.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Simultaneous noninvasive quantification of redox and downstream glycolytic fluxes reveals compartmentalized brain metabolism.

  • Authors : Patel S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Subjects: Oxidation-Reduction* ; Glycolysis* ; Brain*/Brain*/Brain*/metabolism

  • Source: Science advances [Sci Adv] 2024 Dec 20; Vol. 10 (51), pp. eadr2058. Date of Electronic Publication: 2024 Dec 20.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

p53 terminates the regenerative fetal-like state after colitis-associated injury.

  • Authors : Hartl K; Medical Department, Division of Gastroenterology and Hepatology, Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; Regeneration*

  • Source: Science advances [Sci Adv] 2024 Oct 25; Vol. 10 (43), pp. eadp8783. Date of Electronic Publication: 2024 Oct 25.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma.

  • Authors : Galvan C; Department of Molecular Cell and Developmental Biology, UCLA, Los Angeles, CA 90095, USA.; Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA.

Subjects: Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/metabolism ; Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/pathology ; Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/genetics

  • Source: Science advances [Sci Adv] 2024 Sep 20; Vol. 10 (38), pp. eadn2806. Date of Electronic Publication: 2024 Sep 20.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Academic Journal

Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.

  • Authors : Minhas PS; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism

  • Source: Science (New York, N.Y.) [Science] 2024 Aug 23; Vol. 385 (6711), pp. eabm6131. Date of Electronic Publication: 2024 Aug 23.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity.

  • Authors : Xu K; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Immunology and Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA.

Subjects: Glycolysis*; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology ; Lactate Dehydrogenase 5/Lactate Dehydrogenase 5/Lactate Dehydrogenase 5/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2021 Jan 22; Vol. 371 (6527), pp. 405-410.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche.

  • Authors : Liu Z; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.; Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism ; Glycolysis*; Animals

  • Source: Science translational medicine [Sci Transl Med] 2020 Aug 05; Vol. 12 (555).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Academic Journal

p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators.

  • Authors : Birts CN; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, SO16 6YD England, UK.; Institute for Life Sciences, University of Southampton, SO17 1BJ England, UK.

Subjects: Gene Expression Regulation, Neoplastic* ; Glycolysis*; NAD/NAD/NAD/*metabolism

  • Source: Science signaling [Sci Signal] 2020 May 05; Vol. 13 (630). Date of Electronic Publication: 2020 May 05.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Academic Journal

Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β.

  • Authors : Yin X; Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.; Choudhury M

Subjects: Glycolysis* ; Signal Transduction*; Hexokinase/Hexokinase/Hexokinase/*metabolism

  • Source: Science signaling [Sci Signal] 2019 Dec 17; Vol. 12 (612). Date of Electronic Publication: 2019 Dec 17.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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