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Academic Journal

Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling.

  • Authors : Manchanda Y; Section of Cell Biology and Functional Genomics, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, UK.; ElEid L

Subjects: Signal Transduction* ; Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/metabolism ; Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/genetics

  • Source: Science signaling [Sci Signal] 2024 Jul 02; Vol. 17 (843), pp. eabq7038. Date of Electronic Publication: 2024 Jul 02.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication

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Academic Journal

Winning researchers unlocked GLP-1 drugs for obesity.

Subjects: Anti-Obesity Agents*/Anti-Obesity Agents*/Anti-Obesity Agents*/therapeutic use ; Awards and Prizes* ; Glucagon-Like Peptide 1*/Glucagon-Like Peptide 1*/Glucagon-Like Peptide 1*/therapeutic use

  • Source: Science (New York, N.Y.) [Science] 2024 May 31; Vol. 384 (6699), pp. 968-970. Date of Electronic Publication: 2024 May 30.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Periodical

Obesity meets its match.

Subjects: Anti-Obesity Agents*/Anti-Obesity Agents*/Anti-Obesity Agents*/therapeutic use ; Obesity*/Obesity*/Obesity*/epidemiology ; Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/agonists

  • Source: Science (New York, N.Y.) [Science] 2023 Dec 15; Vol. 382 (6676), pp. 1226-1227. Date of Electronic Publication: 2023 Dec 14.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Editorial & Opinion

More questions than answers.

  • Authors : Thorp HH; H. Holden Thorp Editor-in-Chief, Science journals.

Subjects: Obesity*/Obesity*/Obesity*/drug therapy ; Obesity*/Obesity*/Obesity*/epidemiology ; Obesity*/Obesity*/Obesity*/psychology

  • Source: Science (New York, N.Y.) [Science] 2023 Dec 15; Vol. 382 (6676), pp. 1213. Date of Electronic Publication: 2023 Dec 14.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism.

  • Authors : Huang Z; National Engineering Laboratory for Brain-inspired Intelligence Technology and Application, School of Information Science and Technology, University of Science and Technology of China, Anhui, China.; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China.

Subjects: Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/metabolism ; Hypothalamus*/Hypothalamus*/Hypothalamus*/metabolism; Blood Glucose/Blood Glucose/Blood Glucose/metabolism

  • Source: Science advances [Sci Adv] 2022 Jun 10; Vol. 8 (23), pp. eabn5345. Date of Electronic Publication: 2022 Jun 08.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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Editorial & Opinion

Turning the tide on obesity?

  • Authors : Bulik CM; Cynthia M. Bulik is a professor in the Department of Psychiatry and the Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, and in the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Hardaway JA

Subjects: Obesity*/Obesity*/Obesity*/drug therapy ; Anti-Obesity Agents*/Anti-Obesity Agents*/Anti-Obesity Agents*/therapeutic use ; Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/agonists

  • Source: Science (New York, N.Y.) [Science] 2023 Aug 04; Vol. 381 (6657), pp. 463. Date of Electronic Publication: 2023 Aug 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Academic Journal

Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist.

Subjects: Intestinal Absorption*; Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/*agonists ; Glucagon-Like Peptides/Glucagon-Like Peptides/Glucagon-Like Peptides/*pharmacology

  • Source: Science translational medicine [Sci Transl Med] 2018 Nov 14; Vol. 10 (467).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Academic Journal

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus.

  • Authors : Botfield HF; Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TH, UK.

Subjects: Intracranial Pressure*/Intracranial Pressure*/Intracranial Pressure*/drug effects; Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/*agonists ; Hydrocephalus/Hydrocephalus/Hydrocephalus/*drug therapy

  • Source: Science translational medicine [Sci Transl Med] 2017 Aug 23; Vol. 9 (404).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Academic Journal

GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats.

  • Authors : Fortin SM; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lipsky RK

Subjects: Appetite Depressants*/Appetite Depressants*/Appetite Depressants*/pharmacology ; GABAergic Neurons*/GABAergic Neurons*/GABAergic Neurons*/metabolism ; Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/Glucagon-Like Peptide-1 Receptor*/metabolism

  • Source: Science translational medicine [Sci Transl Med] 2020 Mar 04; Vol. 12 (533).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication

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Academic Journal

Targeted delivery of antisense oligonucleotides to pancreatic β-cells.

  • Authors : Ämmälä C; Cardiovascular Renal and Metabolic Diseases, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.; Drury WJ 3rd

Subjects: Drug Delivery Systems/Drug Delivery Systems/Drug Delivery Systems/*methods ; Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/Glucagon-Like Peptide-1 Receptor/*metabolism ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*drug effects

  • Source: Science advances [Sci Adv] 2018 Oct 17; Vol. 4 (10), pp. eaat3386. Date of Electronic Publication: 2018 Oct 17 (Print Publication: 2018).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication

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  • 1-10 of  62 results for ""GLUCAGON-like peptide-1 receptor""