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Complete genome sequence of the apicomplexan, Cryptosporidium parvum.

• Authors : Abrahamsen MS; Department of Veterinary and Biomedical Science, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA. ; Templeton TJ

Subjects: Genome, Protozoan*; Cryptosporidium parvum/Cryptosporidium parvum/Cryptosporidium parvum/*genetics ; Cryptosporidium parvum/Cryptosporidium parvum/Cryptosporidium parvum/*metabolism

• Source: Science (New York, N.Y.) [Science] 2004 Apr 16; Vol. 304 (5669), pp. 441-5. Date of Electronic Publication: 2004 Mar 25.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.

• Authors : Vinayak, Sumiti; Jumani, Rajiv S.; Miller, Peter

Subjects: CRYPTOSPORIDIUM; CHAGAS' disease; CRYPTOSPORIDIUM parvum

• Source: Science Translational Medicine; 9/30/2020, Vol. 12 Issue 563, p1-13, 13p

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Education Full Text (H.W. Wilson)

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Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.

• Authors : Caldwell, Nicola; Peet, Caroline; Miller, Peter

Subjects: CHILD mortality; CRYPTOSPORIDIOSIS; COMMUNICABLE diseases

• Source: Science Translational Medicine; 10/23/2024, Vol. 16 Issue 770, p1-12, 12p

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Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.

• Authors : Swale, Christopher; Bellini, Valeria; Bowler, Matthew W.

Subjects: TOXOPLASMA gondii; PLASMODIUM falciparum; CRYPTOSPORIDIUM

• Source: Science Translational Medicine; 8/3/2022, Vol. 14 Issue 656, p1-17, 17p

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RESEARCH.

• Authors : B. E. L.; M. S. L.; D. J.

• Source: Science; 6/3/2022, Vol. 376 Issue 6597, p1063-1065, 3p, 3 Color Photographs

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Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment.

• Authors : Riba, Ambre; Hassani, Kasra; Walker, Alesia

Subjects: GUT microbiome; LIPID metabolism; BILE

• Source: Science Translational Medicine; 10/14/2020, Vol. 12 Issue 565, p1-15, 15p

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Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection.

• Authors : Swale, Christopher; Bougdour, Alexandre; Gnahoui-David, Audrey

Subjects: CRYPTOSPORIDIOSIS; INFECTION prevention; INTESTINAL parasites

• Source: Science Translational Medicine; 11/6/2019, Vol. 11 Issue 517, p1-11, 11p

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The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.

• Authors : Herman, Jonathan D.; Pepper, Lauren R.; Cortese, Joseph F.

Subjects: TRANSFER RNA; PLASMODIUM falciparum; LIGASES

• Source: Science Translational Medicine; 5/20/2015, Vol. 7 Issue 288, p1-9, 9p, 1 Color Photograph, 1 Diagram, 3 Graphs

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Evolution of the TSC1/TSC2-TOR Signaling Pathway.

• Authors : Serfontein, Jaco; Ellen R. Nisbet, R.; Howe, Christopher J.

• Source: Science Signaling; 6/29/2010, Vol. 3 Issue 128, p1-6, 6p

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