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Academic Journal

Role for Kruppel-like factor 4 in determining the outcome of p53 response to DNA damage.

  • Authors : Zhou Q; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, State Key Laboratory of Molecular Oncology, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Hong Y

Subjects: Apoptosis* ; DNA Damage* ; Gene Expression Regulation, Neoplastic*

  • Source: Cancer research [Cancer Res] 2009 Nov 01; Vol. 69 (21), pp. 8284-92. Date of Electronic Publication: 2009 Oct 13.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells.

  • Authors : Wei D; Departments of Gastrointestinal Medical Oncology and Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.; Kanai M

Subjects: Cyclin-Dependent Kinase Inhibitor p27/Cyclin-Dependent Kinase Inhibitor p27/Cyclin-Dependent Kinase Inhibitor p27/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism ; Pancreatic Neoplasms/Pancreatic Neoplasms/Pancreatic Neoplasms/*prevention & control

  • Source: Cancer research [Cancer Res] 2008 Jun 15; Vol. 68 (12), pp. 4631-9.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Kruppel-like factor 4 is a novel mediator of selenium in growth inhibition.

  • Authors : Liu S; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Zhang H

Subjects: Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism ; Selenium/Selenium/Selenium/*pharmacology; Bromodeoxyuridine/Bromodeoxyuridine/Bromodeoxyuridine/metabolism

  • Source: Molecular cancer research : MCR [Mol Cancer Res] 2008 Feb; Vol. 6 (2), pp. 306-13.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model:

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Academic Journal

Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development.

  • Authors : Najm P; VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.

Subjects: Gene Expression Regulation, Neoplastic* ; Mutation*; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*genetics

  • Source: Cancer research [Cancer Res] 2021 Aug 15; Vol. 81 (16), pp. 4218-4229. Date of Electronic Publication: 2021 Jul 02.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness.

  • Authors : Ganguly K; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska.; Krishn SR

Subjects: Gene Expression Regulation, Neoplastic*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/Carcinoma, Pancreatic Ductal/*pathology

  • Source: Cancer research [Cancer Res] 2021 Jan 01; Vol. 81 (1), pp. 91-102. Date of Electronic Publication: 2020 Oct 30.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Hypoxic Cancer-Secreted Exosomal miR-182-5p Promotes Glioblastoma Angiogenesis by Targeting Kruppel-like Factor 2 and 4.

  • Authors : Li J; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.; Yuan H

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*pathology ; Exosomes/Exosomes/Exosomes/*genetics ; Glioblastoma/Glioblastoma/Glioblastoma/*pathology

  • Source: Molecular cancer research : MCR [Mol Cancer Res] 2020 Aug; Vol. 18 (8), pp. 1218-1231. Date of Electronic Publication: 2020 May 04.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model:

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Academic Journal

NME1 Drives Expansion of Melanoma Cells with Enhanced Tumor Growth and Metastatic Properties.

  • Authors : Wang Y; School of Medicine, University of Maryland-Baltimore, Department of Biochemistry and Molecular Biology, Baltimore, Maryland.; Leonard MK

Subjects: Cell Proliferation* ; Gene Expression Regulation, Neoplastic*; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*secondary

  • Source: Molecular cancer research : MCR [Mol Cancer Res] 2019 Aug; Vol. 17 (8), pp. 1665-1674. Date of Electronic Publication: 2019 May 23.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model:

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Academic Journal

Role of Krüppel-like Factor 4-p21 CIP1 Axis in Breast Cancer Stem-like Cell Inhibition by Benzyl Isothiocyanate.

  • Authors : Kim SH; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Singh SV

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Cyclin-Dependent Kinase Inhibitor p21/Cyclin-Dependent Kinase Inhibitor p21/Cyclin-Dependent Kinase Inhibitor p21/*metabolism ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*drug effects

  • Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2019 Mar; Vol. 12 (3), pp. 125-134. Date of Electronic Publication: 2019 Feb 05.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model:

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Academic Journal

Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium-specific Deletion of Klf4 .

  • Authors : Yang VW; Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York. .; Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, New York.

Subjects: Colitis/Colitis/Colitis/*genetics ; Colitis/Colitis/Colitis/*metabolism ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics

  • Source: Molecular cancer research : MCR [Mol Cancer Res] 2019 Jan; Vol. 17 (1), pp. 165-176. Date of Electronic Publication: 2018 Aug 14.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model:

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Academic Journal

Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.

  • Authors : Lu H; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Subjects: Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/*metabolism ; Hypoxia-Inducible Factor 1/Hypoxia-Inducible Factor 1/Hypoxia-Inducible Factor 1/*metabolism ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*physiology

  • Source: Cancer research [Cancer Res] 2018 Aug 01; Vol. 78 (15), pp. 4191-4202. Date of Electronic Publication: 2018 Jun 07.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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