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Academic Journal

RAS Drives Malignancy through Altered Stem Cell/Microenvironment Cross-talk.

Subjects: Genes, ras*/Genes, ras*/Genes, ras*/genetics ; Genes, ras*/Genes, ras*/Genes, ras*/physiology ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: Cancer discovery [Cancer Discov] 2023 Feb 06; Vol. 13 (2), pp. OF4.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model:

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Academic Journal

MOB3A Bypasses BRAF and RAS Oncogene-Induced Senescence by Engaging the Hippo Pathway.

  • Authors : Dutchak K; Department of Biology, McGill University, Stewart Biology, Montréal QC, Canada.; Garnett S

Subjects: Genes, ras* ; Microtubule-Associated Proteins*/Microtubule-Associated Proteins*/Microtubule-Associated Proteins*/metabolism ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/genetics

  • Source: Molecular cancer research : MCR [Mol Cancer Res] 2022 May 04; Vol. 20 (5), pp. 770-781.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model:

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Academic Journal

NRAS Status Determines Sensitivity to SHP2 Inhibitor Combination Therapies Targeting the RAS-MAPK Pathway in Neuroblastoma.

  • Authors : Valencia-Sama I; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Cell Biology Program, The Hospital for Sick Children, Toronto, Canada.

Subjects: Genes, ras*; Mitogen-Activated Protein Kinase Kinases/Mitogen-Activated Protein Kinase Kinases/Mitogen-Activated Protein Kinase Kinases/*genetics ; Neoplasm Recurrence, Local/Neoplasm Recurrence, Local/Neoplasm Recurrence, Local/*drug therapy

  • Source: Cancer research [Cancer Res] 2020 Aug 15; Vol. 80 (16), pp. 3413-3423. Date of Electronic Publication: 2020 Jun 25.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma.

  • Authors : Li Y; Department of Biochemistry & Molecular Medicine, George Washington Cancer Center, George Washington University School of Medicine & Health Sciences, Washington, D.C.; Zhang X

Subjects: Genes, ras* ; Transcriptional Activation*; Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*genetics

  • Source: Cancer research [Cancer Res] 2020 Aug 15; Vol. 80 (16), pp. 3265-3278. Date of Electronic Publication: 2020 Jun 15.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

NRAS -Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3K α .

  • Authors : Dolgikh N; Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Frankfurt, Germany.; Hugle M

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Genes, ras* ; Mutation*

  • Source: Cancer research [Cancer Res] 2018 Apr 15; Vol. 78 (8), pp. 2000-2013. Date of Electronic Publication: 2018 Feb 06.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer.

  • Authors : Zhang D; Department of Gynecology and Obstetrics, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China.; Center for Research on Reproduction & Women's Health, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Subjects: Genes, ras*; Neoplasms/Neoplasms/Neoplasms/*genetics ; RNA, Long Noncoding/RNA, Long Noncoding/RNA, Long Noncoding/*genetics

  • Source: Cancer research [Cancer Res] 2017 Jul 15; Vol. 77 (14), pp. 3745-3757. Date of Electronic Publication: 2017 May 04.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Differentiated State of Initiating Tumor Cells Is Key to Distinctive Immune Responses Seen in H-Ras G12V -Induced Squamous Tumors.

  • Authors : Podolsky MA; The Pennsylvania State University, The Huck Institutes of the Life Sciences, State College, Pennsylvania.; Bailey JT

Subjects: Genes, ras*; Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*etiology ; Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*metabolism

  • Source: Cancer immunology research [Cancer Immunol Res] 2017 Mar; Vol. 5 (3), pp. 198-210. Date of Electronic Publication: 2017 Jan 30.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model:

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Academic Journal

Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.

  • Authors : Thiem S; Cancer and Inflammation, Olivia Newton-John Cancer Research Institute and School of Cancer Medicine La Trobe University, Heidelberg, Australia.; Eissmann MF

Subjects: Genes, ras* ; Oncogenes*; STAT3 Transcription Factor/STAT3 Transcription Factor/STAT3 Transcription Factor/*genetics

  • Source: Cancer research [Cancer Res] 2016 Apr 15; Vol. 76 (8), pp. 2277-87. Date of Electronic Publication: 2016 Feb 02.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Activated KRAS Cooperates with MLL-AF4 to Promote Extramedullary Engraftment and Migration of Cord Blood CD34+ HSPC But Is Insufficient to Initiate Leukemia.

  • Authors : Prieto C; Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.; Stam RW

Subjects: Genes, ras*; Antigens, CD34/Antigens, CD34/Antigens, CD34/*blood ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

  • Source: Cancer research [Cancer Res] 2016 Apr 15; Vol. 76 (8), pp. 2478-89. Date of Electronic Publication: 2016 Feb 02.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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Academic Journal

Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations.

  • Authors : Riquelme E; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer, Houston, Texas.; Behrens C

Subjects: Genes, ras* ; MAP Kinase Signaling System* ; Mutation*

  • Source: Cancer research [Cancer Res] 2016 Feb 01; Vol. 76 (3), pp. 675-85. Date of Electronic Publication: 2015 Dec 16.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model:

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