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Language : english Publisher : elsevier Subject : albumins Subject : blood plasma Subject : microsomes Subject : serum albumin Filter by : Subject Phrase
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Academic Journal

In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018.

  • Authors : Gamage TF; RTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, USA.; Barrus DG

Subjects: Behavior, Animal/Behavior, Animal/Behavior, Animal/*drug effects ; Body Temperature/Body Temperature/Body Temperature/*drug effects ; Cannabinoid Receptor Agonists/Cannabinoid Receptor Agonists/Cannabinoid Receptor Agonists/*pharmacokinetics

  • Source: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2020 Jun; Vol. 193, pp. 172918. Date of Electronic Publication: 2020 Apr 02.Publisher: Elsevier Country of Publication: United States NLM ID: 0367050 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Vitamin E analogues differentially inhibit human cytochrome P450 3A (CYP3A)-mediated oxidative metabolism of lithocholic acid: Impact of δ-tocotrienol on lithocholic acid cytotoxicity.

  • Authors : Wong SY; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore.; Teo JSM

Subjects: Cytochrome P-450 CYP3A Inhibitors/Cytochrome P-450 CYP3A Inhibitors/Cytochrome P-450 CYP3A Inhibitors/*pharmacology ; Lithocholic Acid/Lithocholic Acid/Lithocholic Acid/*toxicity ; Microsomes/Microsomes/Microsomes/*drug effects

  • Source: Toxicology [Toxicology] 2019 Jul 01; Vol. 423, pp. 62-74. Date of Electronic Publication: 2019 May 15.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

A perspective on the development of the Ames Salmonella/mammalian-microsome mutagenicity assay.

  • Authors : Mortelmans K; SRI International, Menlo Park, CA, 94025, United States. Electronic address: .

Subjects: Mammals/Mammals/Mammals/*microbiology ; Microsomes/Microsomes/Microsomes/*drug effects ; Mutagenesis/Mutagenesis/Mutagenesis/*drug effects

  • Source: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2019 May; Vol. 841, pp. 14-16. Date of Electronic Publication: 2019 Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101632149 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Terfenadone is a strong inhibitor of CYP2J2 present in the human liver and intestinal microsomes.

  • Authors : Lee E; BK21 Plus KNU Multi-Omics Based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea.; Kim JH

Subjects: Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism ; Intestines/Intestines/Intestines/*drug effects ; Liver/Liver/Liver/*drug effects

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2018 Jun; Vol. 33 (3), pp. 159-163. Date of Electronic Publication: 2018 Mar 15.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction.

  • Authors : Meng F; Chinese Medicine Toxicological Laboratory, Institute of Traditional Chinese Medicine, Drug Safety Evaluation Center, Heilongjiang University of Chinese Medicine, Harbin 150040, China.; Li Y

Subjects: Coumarins/Coumarins/Coumarins/*chemistry ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*chemistry ; Microsomes/Microsomes/Microsomes/*drug effects

  • Source: Fitoterapia [Fitoterapia] 2017 Mar; Vol. 117, pp. 118-125. Date of Electronic Publication: 2016 Nov 30.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.

  • Authors : Saghir SA; Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI 48674, USA. ; Zhang F

Subjects: Benzene Derivatives*/Benzene Derivatives*/Benzene Derivatives*/pharmacokinetics ; Benzene Derivatives*/Benzene Derivatives*/Benzene Derivatives*/toxicity ; Environmental Pollutants*/Environmental Pollutants*/Environmental Pollutants*/pharmacokinetics

  • Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2010 Jul-Aug; Vol. 57 (2-3), pp. 129-35. Date of Electronic Publication: 2010 Jan 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The effect of beta-naphthoflavone on the metabolism of amiodarone by hepatic and extra-hepatic microsomes.

  • Authors : Elsherbiny ME; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2N8.; El-Kadi AO

Subjects: Amiodarone/Amiodarone/Amiodarone/*metabolism ; Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*metabolism ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*toxicity

  • Source: Toxicology letters [Toxicol Lett] 2010 Jun 02; Vol. 195 (2-3), pp. 147-54. Date of Electronic Publication: 2010 Apr 01.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung.

  • Authors : Stiborová M; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40 Prague 2, Czech Republic. ; Dracínská H

Subjects: DNA Adducts*; Benz(a)Anthracenes/Benz(a)Anthracenes/Benz(a)Anthracenes/*metabolism ; Benz(a)Anthracenes/Benz(a)Anthracenes/Benz(a)Anthracenes/*pharmacology

  • Source: Mutation research [Mutat Res] 2009 May 31; Vol. 676 (1-2), pp. 93-101. Date of Electronic Publication: 2009 May 03.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0400763 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Cis astaxanthin and especially 9-cis astaxanthin exhibits a higher antioxidant activity in vitro compared to the all-trans isomer.

  • Authors : Liu X; Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Science, Nagoya University, Nagoya 464-8601, Japan.; Osawa T

Subjects: Erythrocyte Membrane/Erythrocyte Membrane/Erythrocyte Membrane/*metabolism ; Microsomes/Microsomes/Microsomes/*metabolism ; Reactive Oxygen Species/Reactive Oxygen Species/Reactive Oxygen Species/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2007 May 25; Vol. 357 (1), pp. 187-93. Date of Electronic Publication: 2007 Mar 28.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.

  • Authors : Nishimura M; Department of Drug Metabolism, Division of Pharmacology, Drug Safety and Metabolism, Otsuka Pharmaceutical Factory Inc., Naruto, Tokushima, Japan. ; Koeda A

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*genetics ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*drug effects ; Hepatocytes/Hepatocytes/Hepatocytes/*drug effects

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2006 Aug; Vol. 21 (4), pp. 297-307.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print Cited Medium: Print

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  • 1-10 of  199 results for ""Microsomes drug effects""