Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Pharmacokinetics of oltipraz in mutant Nagase analbuminemic rats.

  • Authors : Bae SK; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.; Kang HE

Subjects: Acetylglucosaminidase/Acetylglucosaminidase/Acetylglucosaminidase/*genetics ; Albumins/Albumins/Albumins/*deficiency ; Pyrazines/Pyrazines/Pyrazines/*pharmacokinetics

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2006 May; Vol. 95 (5), pp. 998-1005.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Print

Record details

×
Academic Journal

Interaction of plasma proteins with cytochromes P450 mediated metabolic reactions: inhibition by human serum albumin and alpha-globulins of the debrisoquine 4-hydroxylation (CYP2D) in liver microsomes of human, hamster and rat.

  • Authors : Ishii M; Department of Pharmacology, University of Toronto, Faculty of Medicine, Medical Science Building, 8 Taddlecreek Road, M5S 1A8, Toronto, ONT, Canada.; Xu BQ

Subjects: Adrenergic Agents/Adrenergic Agents/Adrenergic Agents/*metabolism ; Alpha-Globulins/Alpha-Globulins/Alpha-Globulins/*pharmacology ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*metabolism

  • Source: Toxicology letters [Toxicol Lett] 2001 Mar 08; Vol. 119 (3), pp. 219-25.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print Cited Medium: Print

Record details

×
Academic Journal

Microsomal activation to mutagens of antischistosomal methyl thioxanthenones and initial tests on a possibly non-mutagenic analogue.

Subjects: Microsomes, Liver/Microsomes, Liver/Microsomes, Liver/*metabolism ; Mutagens/Mutagens/Mutagens/*pharmacology ; Schistosomicides/Schistosomicides/Schistosomicides/*pharmacology

  • Source: Mutation research [Mutat Res] 1975 Apr; Vol. 31 (2), pp. 87-95.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0400763 Publication Model: Print Cited Medium: Print

Record details

×
Academic Journal

Chemical evidence for the difference between albumins from microsomes and serum and a possible precursor-product relationship.

Subjects: Albumins*/Albumins*/Albumins*/analysis ; Albumins*/Albumins*/Albumins*/isolation & purification ; Serum Albumin*/Serum Albumin*/Serum Albumin*/analysis

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1974 Nov 27; Vol. 61 (2), pp. 494-501.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print Cited Medium: Print

Record details

×
Academic Journal

Is a liver comparable to a liver? A comparison of different rat-derived S9-fractions with a biotechnological animal-free alternative in the Ames fluctuation assay.

  • Authors : Brendt J; Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.; Crawford SE

Subjects: Liver*/Liver*/Liver*/metabolism ; Mutagens*; Animals

  • Source: The Science of the total environment [Sci Total Environ] 2021 Mar 10; Vol. 759, pp. 143522. Date of Electronic Publication: 2020 Nov 14.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium:

Record details

×
Academic Journal

Optimization of a pre-metabolization procedure using rat liver S9 and cell-extracted S9 in the Ames fluctuation test.

  • Authors : Shao Y; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany; Key Laboratory of the Three Gorges Reservoir Eco-environment, Ministry of Education, Chongqing University, Shazheng street 174, Shapingba, 400044 Chongqing, China. Electronic address: .

Subjects: Mutagens* ; Salmonella typhimurium*/Salmonella typhimurium*/Salmonella typhimurium*/genetics; Animals

  • Source: The Science of the total environment [Sci Total Environ] 2020 Dec 20; Vol. 749, pp. 141468. Date of Electronic Publication: 2020 Aug 06.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium:

Record details

×
Academic Journal

DNA as an in vitro trapping agent for detection of bulky genotoxic metabolites.

  • Authors : Motwani HV; Department of Environmental Science, Stockholm University, SE-106 91 Stockholm, Sweden. Electronic address: .

Subjects: DNA Adducts*/DNA Adducts*/DNA Adducts*/analysis ; DNA Adducts*/DNA Adducts*/DNA Adducts*/chemistry ; DNA Adducts*/DNA Adducts*/DNA Adducts*/metabolism

  • Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2020 Sep 01; Vol. 1152, pp. 122276. Date of Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium:

Record details

×
Academic Journal

A perspective on the development of the Ames Salmonella/mammalian-microsome mutagenicity assay.

  • Authors : Mortelmans K; SRI International, Menlo Park, CA, 94025, United States. Electronic address: .

Subjects: Mammals/Mammals/Mammals/*microbiology ; Microsomes/Microsomes/Microsomes/*drug effects ; Mutagenesis/Mutagenesis/Mutagenesis/*drug effects

  • Source: Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2019 May; Vol. 841, pp. 14-16. Date of Electronic Publication: 2019 Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101632149 Publication Model: Print-Electronic Cited Medium:

Record details

×
Academic Journal

The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene.

  • Authors : Wang D; Division of Toxicology, Wageningen University and Research, 6708WE, Wageningen, the Netherlands. Electronic address: .; Groot A

Subjects: Mutagens*/Mutagens*/Mutagens*/toxicity ; Polycyclic Aromatic Hydrocarbons*/Polycyclic Aromatic Hydrocarbons*/Polycyclic Aromatic Hydrocarbons*/chemistry; Benzo(a)pyrene/Benzo(a)pyrene/Benzo(a)pyrene/toxicity

  • Source: Chemico-biological interactions [Chem Biol Interact] 2022 Aug 25; Vol. 363, pp. 110007. Date of Electronic Publication: 2022 Jun 06.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium:

Record details

×
Academic Journal

Assessment of mutagenic potential of pyrolysis biochars by Ames Salmonella/mammalian-microsomal mutagenicity test.

  • Authors : Anjum R; Leibniz Institute for Agricultural Engineering Potsdam-Bornim e.V., Max-Eyth-Allee 100, D-14469 Potsdam, Germany. Electronic address: .; Krakat N

Subjects: Charcoal/Charcoal/Charcoal/*toxicity ; Mutagens/Mutagens/Mutagens/*analysis; Animals

  • Source: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2014 Sep; Vol. 107, pp. 306-12. Date of Electronic Publication: 2014 Jul 20.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium:

Record details

×
  • 1-10 of  725 results for ""Microsomes""