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Academic Journal

The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats.

  • Authors : Felippe ISA; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, ES, Brazil; Department of Physiology, Faculty of Health & Medical Sciences, University of Auckland, Grafton Campus, Auckland 1023, New Zealand.

Subjects: Antidotes/Antidotes/Antidotes/*pharmacology ; Atropine/Atropine/Atropine/*pharmacology ; Cardiovascular System/Cardiovascular System/Cardiovascular System/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Jan 15; Vol. 389, pp. 114879. Date of Electronic Publication: 2020 Jan 10.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS.

  • Authors : Okuno S; Section of Forensic Medicine, Department of International Health Development, Division of Public Health, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan.; Sakurada K

Subjects: Brain/Brain/Brain/*metabolism ; Chromatography, Liquid/Chromatography, Liquid/Chromatography, Liquid/*methods ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacokinetics

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2008 Feb 15; Vol. 227 (1), pp. 8-15. Date of Electronic Publication: 2007 Sep 29.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Concentrations of 2-hydroxyiminomethyl-N-methylpyridinium ion in plasma and aqueous humor as indices of the toxicity of pralidoxime mesylate (P2S) for the rabbit.

Subjects: Aqueous Humor/Aqueous Humor/Aqueous Humor/*metabolism ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*toxicity; Animals

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1975 Sep; Vol. 33 (3), pp. 559-67.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

EFFECTS OF CERTAIN METABOLICALLY ACTIVE DRUGS AND OXIMES ON TRI-O-CRESYL PHOSPHATE TOXICITY.

Subjects: Antidotes* ; Atropine* ; Cholinesterases*

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1965 Mar; Vol. 7, pp. 227-35.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

EXTENSION OF TRANQUILIZER ACTION BY ANTICHOLINESTERASES.

Subjects: Amphetamine* ; Atropine* ; Cholinesterase Inhibitors*

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1964 Jan; Vol. 6, pp. 1-8.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

ANTIDOTAL ACTION OF PYRIDINIUM OXIMES IN ANTICHOLINESTERASE POISONING; COMPARATIVE EFFECTS OF SOMAN, SARIN, AND NEOSTIGMINE ON NEUROMUSCULAR FUNCTION.

Subjects: Atropine* ; Cholinesterase Inhibitors* ; Enzyme Inhibitors*

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1963 Nov; Vol. 5, pp. 685-701.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

Efficacy of pro-PAM (N-methyl-1,6-dihydropyridine-2-carbaldoxime hydrochloride) as a prophylaxis against organophosphate poisoning.

Subjects: Organophosphate Poisoning*; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*poisoning ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1979 Feb; Vol. 47 (2), pp. 305-11.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

The prophylactic use of l-methyl, 2-hydroxyiminomethylpyridinium methanesulfonate (P2S) in the treatment of organophosphate poisoning.

Subjects: Organophosphate Poisoning*; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*therapeutic use; Animals

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1977 Apr; Vol. 40 (1), pp. 109-14.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

Absence of a protective effect of the oxime 2-PAM toward paraoxon-poisoned honey bees: acetylcholinesterase reactivation not at fault.

  • Authors : Polyzou A; Phytopharmacie, Institut National de la Recherche Agronomique, Avignon Cedex 9, 84914, France.; Froment MT

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Bees/Bees/Bees/*drug effects ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*poisoning

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1998 Sep; Vol. 152 (1), pp. 184-92.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

Phosphotriesterase, pralidoxime-2-chloride (2-PAM) and eptastigmine treatments and their combinations in DFP intoxication.

Subjects: Antidotes/Antidotes/Antidotes/*pharmacology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*poisoning ; Esterases/Esterases/Esterases/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1996 Dec; Vol. 141 (2), pp. 555-60.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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