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Academic Journal

Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells.

  • Authors : Lambert CB; INSERM U620 and Université de Rennes 1, 35043 Rennes, France.; Spire C

Subjects: Gene Expression Profiling*/Gene Expression Profiling*/Gene Expression Profiling*/methods; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/Gene Expression Regulation, Enzymologic/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2009 Feb 01; Vol. 234 (3), pp. 345-60. Date of Electronic Publication: 2008 Nov 21.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation.

  • Authors : Li CC; Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan.; Lii CK

Subjects: Cytochrome P-450 CYP2B1/Cytochrome P-450 CYP2B1/Cytochrome P-450 CYP2B1/*drug effects ; Docosahexaenoic Acids/Docosahexaenoic Acids/Docosahexaenoic Acids/*pharmacology ; Down-Regulation/Down-Regulation/Down-Regulation/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2007 Dec 15; Vol. 225 (3), pp. 329-36. Date of Electronic Publication: 2007 Aug 23.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

EGF receptors of hepatocytes from rats treated with phenobarbital are sensitized to down-regulation by phenobarbital in culture.

  • Authors : Dalton SR; Department of Toxicology, North Carolina State University, Raleigh 27695, USA.; Jirtle RL

Subjects: Aryl Hydrocarbon Hydroxylases*; Down-Regulation/Down-Regulation/Down-Regulation/*drug effects ; ErbB Receptors/ErbB Receptors/ErbB Receptors/*metabolism

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2000 Jun 01; Vol. 165 (2), pp. 115-26.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

Absence of DNA adduct formation by phenobarbital, polychlorinated biphenyls, and chlordane in mouse liver using the 32P-postlabeling assay.

  • Authors : Whysner J; Toxicology and Risk Assessment Program, American Health Foundation, Valhalla, New York 10595, USA.; Montandon F

Subjects: Carcinogens/Carcinogens/Carcinogens/*toxicity ; Chlordan/Chlordan/Chlordan/*toxicity ; DNA Adducts/DNA Adducts/DNA Adducts/*metabolism

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1998 Jan; Vol. 148 (1), pp. 14-23.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

The cytochrome P450 2AA gene cluster in zebrafish (Danio rerio): expression of CYP2AA1 and CYP2AA2 and response to phenobarbital-type inducers.

  • Authors : Kubota A; Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.; Bainy AC

Subjects: Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*biosynthesis ; Enzyme Induction/Enzyme Induction/Enzyme Induction/*drug effects ; Phenobarbital/Phenobarbital/Phenobarbital/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2013 Oct 01; Vol. 272 (1), pp. 172-9. Date of Electronic Publication: 2013 May 29.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Reduced hepatic global hydroxymethylation in mice treated with non-genotoxic carcinogens is transiently reversible with a methyl supplemented diet.

  • Authors : Sharapova T; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States. Electronic address: .; Talaty N

Subjects: Dietary Supplements*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*chemically induced ; Carcinogens/Carcinogens/Carcinogens/*toxicity

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 15; Vol. 415, pp. 115439. Date of Electronic Publication: 2021 Feb 05.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comparative effects of phenobarbital, DDT, and lindane on mouse hepatocyte gap junctional intercellular communication.

  • Authors : Klaunig JE; Department of Pathology, Medical College of Ohio, Toledo 43614.; Ruch RJ

Subjects: Cell Communication/Cell Communication/Cell Communication/*drug effects ; Hydrocarbons, Chlorinated/Hydrocarbons, Chlorinated/Hydrocarbons, Chlorinated/*pharmacology ; Intercellular Junctions/Intercellular Junctions/Intercellular Junctions/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1990 Mar 01; Vol. 102 (3), pp. 553-63.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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Academic Journal

A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents.

  • Authors : Kato Y; Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki, Kagawa 769-2193, Japan. ; Suzuki H

Subjects: Hypnotics and Sedatives/Hypnotics and Sedatives/Hypnotics and Sedatives/*toxicity ; Phenobarbital/Phenobarbital/Phenobarbital/*toxicity ; Thyroxine/Thyroxine/Thyroxine/*blood

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2010 Dec 15; Vol. 249 (3), pp. 238-46. Date of Electronic Publication: 2010 Oct 13.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.

  • Authors : Wieneke N; University of Potsdam, Institute of Nutrition Science, Biochemistry of Nutrition, Arthur-Scheunert-Allee 114-116, D14558 Nuthetal, Germany.; Neuschäfer-Rube F

Subjects: Hepatocytes/Hepatocytes/Hepatocytes/*drug effects ; Hepatocytes/Hepatocytes/Hepatocytes/*metabolism ; PPAR alpha/PPAR alpha/PPAR alpha/*agonists

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2009 Oct 01; Vol. 240 (1), pp. 99-107. Date of Electronic Publication: 2009 Jul 22.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of phenobarbital on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-kappaB.

  • Authors : Tharappel JC; Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40506-0054, USA.; Spear BT

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Carcinogens/Carcinogens/Carcinogens/*toxicity ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2008 Feb 01; Vol. 226 (3), pp. 338-44. Date of Electronic Publication: 2007 Sep 26.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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