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Academic Journal

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans.

  • Authors : Floyd HEE; Community for Open Antimicrobial Drug Discovery, Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.; Kavanagh AM

Subjects: Candida albicans*/Candida albicans*/Candida albicans*/drug effects ; Cryptococcus neoformans*/Cryptococcus neoformans*/Cryptococcus neoformans*/drug effects ; Microbial Sensitivity Tests*/Microbial Sensitivity Tests*/Microbial Sensitivity Tests*/methods

  • Source: Scientific reports [Sci Rep] 2024 Oct 08; Vol. 14 (1), pp. 23407. Date of Electronic Publication: 2024 Oct 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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High throughput screen identifies lysosomal acid phosphatase 2 (ACP2) to regulate IFN-1 responses to potentiate oncolytic VSV∆51 activity.

  • Authors : Wong B; Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa, ON, K1H 8L6, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.

Subjects: Interferon Type I*/Interferon Type I*/Interferon Type I*/metabolism ; Oncolytic Viruses*/Oncolytic Viruses*/Oncolytic Viruses*/genetics ; Acid Phosphatase*/Acid Phosphatase*/Acid Phosphatase*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28284. Date of Electronic Publication: 2024 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Modulation of Ca 2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis.

  • Authors : Sasaki T; Department of Neurology, Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan. .; StemRIM Institute of Regeneration-Inducing Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan. .

Subjects: Receptors, Nicotinic*/Receptors, Nicotinic*/Receptors, Nicotinic*/metabolism ; Neurons*/Neurons*/Neurons*/metabolism ; Neurons*/Neurons*/Neurons*/drug effects

  • Source: Scientific reports [Sci Rep] 2024 Nov 12; Vol. 14 (1), pp. 27667. Date of Electronic Publication: 2024 Nov 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Development of a high-throughput screening system targeting the protein-protein interactions between PRL and CNNM.

  • Authors : Funato Y; Laboratory of Biorecognition Chemistry, Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan. .; Mimura M

Subjects: High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods ; Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/antagonists & inhibitors ; Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/Protein Tyrosine Phosphatases*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 25; Vol. 14 (1), pp. 25432. Date of Electronic Publication: 2024 Oct 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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A robust high-throughput screening system to assess bacterial tyrosine ammonia lyase activity in the context of tyrosine inherited metabolic disorders.

  • Authors : Nulmans I; Liver Therapy & Evolution Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090, Brussels, Belgium. .; Laga CA

Subjects: Ammonia-Lyases*/Ammonia-Lyases*/Ammonia-Lyases*/metabolism ; Ammonia-Lyases*/Ammonia-Lyases*/Ammonia-Lyases*/genetics ; Flavobacterium*/Flavobacterium*/Flavobacterium*/enzymology

  • Source: Scientific reports [Sci Rep] 2024 Sep 27; Vol. 14 (1), pp. 22175. Date of Electronic Publication: 2024 Sep 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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AI is a viable alternative to high throughput screening: a 318-target study.

Subjects: High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods ; Drug Discovery*/Drug Discovery*/Drug Discovery*/methods; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Apr 02; Vol. 14 (1), pp. 7526. Date of Electronic Publication: 2024 Apr 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays.

  • Authors : Parijat P; Randall Centre for Cell and Molecular Biophysics, King's College London, London, SE1 1UL, UK.; British Heart Foundation Centre of Research Excellence, King's College London, London, SE1 1UL, UK.

Subjects: High-Throughput Screening Assays* ; Calcium*; Humans

  • Source: Scientific reports [Sci Rep] 2023 Mar 30; Vol. 13 (1), pp. 5216. Date of Electronic Publication: 2023 Mar 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Streamlining pipeline efficiency: a novel model-agnostic technique for accelerating conditional generative and virtual screening pipelines.

  • Authors : Viswanathan K; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.; Goel M

Subjects: Software* ; High-Throughput Screening Assays*

  • Source: Scientific reports [Sci Rep] 2023 Nov 29; Vol. 13 (1), pp. 21069. Date of Electronic Publication: 2023 Nov 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Generalising from conventional pipelines using deep learning in high-throughput screening workflows.

  • Authors : Garcia Santa Cruz B; National Department of Neurosurgery, Centre Hospitalier de Luxembourg, 4, Rue Ernest Barble, 1210, Luxembourg (City), Luxembourg. .; Interventional Neuroscience Group, Luxembourg Center for Systems Biomedicine, University of Luxembourg, 6, Avenue du Swing, 4367, Belvaux, Luxembourg. .

Subjects: Deep Learning* ; High-Throughput Screening Assays*; Autophagy

  • Source: Scientific reports [Sci Rep] 2022 Jul 06; Vol. 12 (1), pp. 11465. Date of Electronic Publication: 2022 Jul 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells.

  • Authors : Gallant K; National Cancer Institute, NIH, Bethesda, MD, 20892, USA.; Bektas A

Subjects: DNA Damage* ; High-Throughput Screening Assays*/High-Throughput Screening Assays*/High-Throughput Screening Assays*/methods; Biological Assay

  • Source: Scientific reports [Sci Rep] 2022 Apr 15; Vol. 12 (1), pp. 6335. Date of Electronic Publication: 2022 Apr 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  552 results for ""High-Throughput Screening Assays""