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Academic Journal

Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide.

  • Authors : Santamaria S; Department of Immunology and Inflammation, Imperial College London, Du Cane Road, London, W12 0NN, UK. .; Cuffaro D

Subjects: ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism ; Glycoconjugates/Glycoconjugates/Glycoconjugates/*pharmacology ; Sulfonamides/Sulfonamides/Sulfonamides/*pharmacology

  • Source: Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 949. Date of Electronic Publication: 2021 Jan 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis.

  • Authors : Nakamura H; Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science Kanazawa, Ishikawa, Japan. .; Matrix Biology Department, the Kennedy Institute of Rheumatology Division, Imperial College London, Hammersmith, London, UK. .

Subjects: ADAM17 Protein/ADAM17 Protein/ADAM17 Protein/*antagonists & inhibitors ; ADAMTS4 Protein/ADAMTS4 Protein/ADAMTS4 Protein/*antagonists & inhibitors ; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*antagonists & inhibitors

  • Source: Scientific reports [Sci Rep] 2020 Jun 09; Vol. 10 (1), pp. 9288. Date of Electronic Publication: 2020 Jun 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Degrading products of chondroitin sulfate can induce hypertrophy-like changes and MMP-13/ADAMTS5 production in chondrocytes.

  • Authors : Jung YK; Biomedical Research Institute, Gyeongsang National University Hospital, Jinju, Gyeongsangnam-do, Republic of Korea.; Park HR

Subjects: Signal Transduction*; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Nov 01; Vol. 9 (1), pp. 15846. Date of Electronic Publication: 2019 Nov 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.

  • Authors : Santamaria S; From the Centre for Haematology, Imperial College London, Du Cane Road, W12 0NN, London, UK. .; Yamamoto K

Subjects: ADAMTS1 Protein/ADAMTS1 Protein/ADAMTS1 Protein/*chemistry ; ADAMTS4 Protein/ADAMTS4 Protein/ADAMTS4 Protein/*chemistry ; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*chemistry

  • Source: Scientific reports [Sci Rep] 2019 Jul 29; Vol. 9 (1), pp. 10914. Date of Electronic Publication: 2019 Jul 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Differential effects of alendronate on chondrocytes, cartilage matrix and subchondral bone structure in surgically induced osteoarthritis in mice.

  • Authors : Ehrnsperger M; Clinic of Orthopedic Surgery, Exp. Orthopedics, University of Regensburg, ZMB im Biopark 1, Am Biopark 9, Regensburg, Germany.; Taheri S

Subjects: Alendronate*/Alendronate*/Alendronate*/pharmacology ; Alendronate*/Alendronate*/Alendronate*/therapeutic use ; Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/drug effects

  • Source: Scientific reports [Sci Rep] 2024 Oct 23; Vol. 14 (1), pp. 25026. Date of Electronic Publication: 2024 Oct 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of short-term high fat diet on resistin levels and expression of autophagy-related genes in the cartilage of male rats.

Subjects: RESISTIN; HIGH-fat diet; CARTILAGE

  • Source: Scientific Reports; 9/12/2022, Vol. 12 Issue 1, p1-13, 13p

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Academic Journal

The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture System.

  • Authors : Pagani S; Laboratory of Preclinical and Surgical Studies, IRCCS Istituto Ortopedico Rizzoli, via di Barbiano 1/10, 40136, Bologna, Italy.; Minguzzi M

Subjects: Chondrocytes/Chondrocytes/Chondrocytes/*cytology ; Glucosamine/Glucosamine/Glucosamine/*pharmacology ; I-kappa B Kinase/I-kappa B Kinase/I-kappa B Kinase/*genetics

  • Source: Scientific reports [Sci Rep] 2019 Sep 19; Vol. 9 (1), pp. 13603. Date of Electronic Publication: 2019 Sep 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis.

  • Authors : Cosenza S; IRMB, INSERM, Montpellier University, Montpellier, France.; Ruiz M

Subjects: Cell-Derived Microparticles/Cell-Derived Microparticles/Cell-Derived Microparticles/*transplantation ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Exosomes/Exosomes/Exosomes/*transplantation

  • Source: Scientific reports [Sci Rep] 2017 Nov 24; Vol. 7 (1), pp. 16214. Date of Electronic Publication: 2017 Nov 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1.

  • Authors : Cui X; Zhongshan Hospital, Xiamen University, Xiamen, Fujian, 361000, China.; Wang S

Subjects: Gene Expression*; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Extracellular Matrix Proteins/Extracellular Matrix Proteins/Extracellular Matrix Proteins/*genetics

  • Source: Scientific reports [Sci Rep] 2016 Mar 14; Vol. 6, pp. 23117. Date of Electronic Publication: 2016 Mar 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model.

  • Authors : Higuchi Y; Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Nishida Y

Subjects: Gene Knockdown Techniques*; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*enzymology ; Hyaluronoglucosaminidase/Hyaluronoglucosaminidase/Hyaluronoglucosaminidase/*metabolism

  • Source: Scientific reports [Sci Rep] 2017 Aug 01; Vol. 7 (1), pp. 7028. Date of Electronic Publication: 2017 Aug 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  13 results for ""ADAMTS5 Protein""