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Academic Journal

Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer-dimer interface.

  • Authors : Carney DW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037.

Subjects: Chemistry Techniques, Synthetic*; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*chemical synthesis ; Tubulin/Tubulin/Tubulin/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Aug 30; Vol. 113 (35), pp. 9691-8. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast.

  • Authors : Qu Y; Department of Biological Sciences and.; Easson ML

Subjects: Metabolic Engineering*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemistry ; Catharanthus/Catharanthus/Catharanthus/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 May 12; Vol. 112 (19), pp. 6224-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The C terminus of beta-tubulin regulates vinblastine-induced tubulin polymerization.

  • Authors : Rai SS; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0830, USA.; Wolff J

Subjects: Tubulin/Tubulin/Tubulin/*chemistry ; Tubulin/Tubulin/Tubulin/*metabolism ; Vinblastine/Vinblastine/Vinblastine/*pharmacology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1998 Apr 14; Vol. 95 (8), pp. 4253-7.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Nerve growth factor prevents vinblastine destructive effects on sympathetic ganglia in newborn mice.

Subjects: Ganglia, Autonomic/Ganglia, Autonomic/Ganglia, Autonomic/*drug effects ; Microtubules/Microtubules/Microtubules/*drug effects ; Nerve Growth Factors/Nerve Growth Factors/Nerve Growth Factors/*pharmacology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1977 Dec; Vol. 74 (12), pp. 5559-63.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Precipitation of proteins by vinblastine and calcium ions.

Subjects: Brain Chemistry* ; Calcium* ; Chemical Precipitation*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1970 Jul; Vol. 66 (3), pp. 807-14.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Effect of vinblastine on distribution of murine leukemia virus-derived membrane-associated antigens.

Subjects: Antigens, Surface/Antigens, Surface/Antigens, Surface/*immunology ; Antigens, Viral/Antigens, Viral/Antigens, Viral/*immunology ; Moloney murine leukemia virus/Moloney murine leukemia virus/Moloney murine leukemia virus/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1981 Oct; Vol. 78 (10), pp. 6266-70.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Subjects: Genes* ; Transcription, Genetic*; Colchicine/Colchicine/Colchicine/*pharmacology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1987 May; Vol. 84 (9), pp. 3004-8.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.

  • Authors : Horio M; Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892.; Gottesman MM

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Vinblastine/Vinblastine/Vinblastine/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1988 May; Vol. 85 (10), pp. 3580-4.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Tubulin aggregation and disaggregation: mediation by two distinct vinblastine-binding sites.

Subjects: Glycoproteins/Glycoproteins/Glycoproteins/*metabolism ; Tubulin/Tubulin/Tubulin/*metabolism ; Vinblastine/Vinblastine/Vinblastine/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1976 Jul; Vol. 73 (7), pp. 2375-8.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Membrane microfilaments of erythrocytes: alteration in intact cells reproduces the hereditary spherocytosis syndrome (vinblastine-colchicine-strychnine-electron microscopy-cell rigidity).

Subjects: Erythrocytes, Abnormal*/Erythrocytes, Abnormal*/Erythrocytes, Abnormal*/metabolism; Erythrocytes/Erythrocytes/Erythrocytes/*drug effects ; Spherocytosis, Hereditary/Spherocytosis, Hereditary/Spherocytosis, Hereditary/*blood

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1972 Feb; Vol. 69 (2), pp. 471-4.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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