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Publication : proceedings of the national academy of sciences of the united states of america
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Academic Journal

Measurement of α-synuclein as protein cargo in plasma extracellular vesicles.

  • Authors : Gilboa T; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/blood ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 05; Vol. 121 (45), pp. e2408949121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease.

  • Authors : Williams D; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850.; Glasstetter LM

Subjects: Glucosylceramidase*/Glucosylceramidase*/Glucosylceramidase*/metabolism ; Glucosylceramidase*/Glucosylceramidase*/Glucosylceramidase*/genetics ; Gaucher Disease*/Gaucher Disease*/Gaucher Disease*/drug therapy

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Oct 15; Vol. 121 (42), pp. e2406009121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Natural variation in age-related dopamine neuron degeneration is glutathione dependent and linked to life span.

  • Authors : Coleman CR; Jungers Center for Neurosciences, Department of Neurology, Oregon Health and Science University, Portland, OR 97239.; Pallos J

Subjects: Glutathione*/Glutathione*/Glutathione*/metabolism ; Dopaminergic Neurons*/Dopaminergic Neurons*/Dopaminergic Neurons*/metabolism ; Dopaminergic Neurons*/Dopaminergic Neurons*/Dopaminergic Neurons*/pathology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Oct 15; Vol. 121 (42), pp. e2403450121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The primary cilium of cholinergic neurons may be a linchpin in the progression of Parkinson's Disease.

  • Authors : Uribe-Cano S; City University of New York (CUNY) Graduate Center, Neuroscience Collaborative, New York, NY 10016.; Department of Molecular, Cellular and Biomedical Sciences, The City University of New York (CUNY) School of Medicine, New York, NY 10031.

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Cilia*/Cilia*/Cilia*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 24; Vol. 121 (39), pp. e2414226121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Olfactory deficit and gastrointestinal dysfunction precede motor abnormalities in alpha-Synuclein G51D knock-in mice.

  • Authors : Kim Y; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030.; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 24; Vol. 121 (39), pp. e2406479121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson's disease.

  • Authors : Khan SS; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305-5307.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.

Subjects: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism ; Cilia*/Cilia*/Cilia*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Aug 06; Vol. 121 (32), pp. e2402206121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making.

  • Authors : Hoy CW; Department of Neurology, University of California, San Francisco, CA 94143.; de Hemptinne C

Subjects: Prefrontal Cortex*/Prefrontal Cortex*/Prefrontal Cortex*/physiology ; Prefrontal Cortex*/Prefrontal Cortex*/Prefrontal Cortex*/physiopathology ; Reward*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 30; Vol. 121 (31), pp. e2322869121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Parkinson's-linked LRRK2-G2019S derails AMPAR trafficking, mobility, and composition in striatum with cell-type and subunit specificity.

  • Authors : Gupta S; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.

Subjects: Corpus Striatum*/Corpus Striatum*/Corpus Striatum*/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 09; Vol. 121 (28), pp. e2317833121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Subthalamic nucleus-language network connectivity predicts dopaminergic modulation of speech function in Parkinson's disease.

  • Authors : Cai W; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305.; Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA 94305.

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/physiopathology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy ; Subthalamic Nucleus*/Subthalamic Nucleus*/Subthalamic Nucleus*/physiopathology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 28; Vol. 121 (22), pp. e2316149121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons.

  • Authors : Mohd Rafiq N; Department of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.; Department of Cell biology, Yale University School of Medicine, New Haven, CT 06510.

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/metabolism ; Parkinsonian Disorders*/Parkinsonian Disorders*/Parkinsonian Disorders*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 23; Vol. 121 (17), pp. e2318943121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  1,308 results for ""SYMPTOMATIC Parkinson's disease""