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Academic Journal

The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA.

Subjects: Diabetes Mellitus, Type 1/Diabetes Mellitus, Type 1/Diabetes Mellitus, Type 1/*genetics ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*immunology ; RNA, Long Noncoding/RNA, Long Noncoding/RNA, Long Noncoding/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Apr 21; Vol. 117 (16), pp. 9022-9031. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.

  • Authors : Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029; .

Subjects: COVID-19/COVID-19/COVID-19/*metabolism ; Interferons/Interferons/Interferons/*metabolism ; Nuclear Pore/Nuclear Pore/Nuclear Pore/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 28344-28354. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs.

  • Authors : Wang S; Lady Davis Institute for Medical Research, McGill University, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada;

Subjects: Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*pharmacology ; Doxorubicin/Doxorubicin/Doxorubicin/*pharmacology ; Peptide Chain Initiation, Translational/Peptide Chain Initiation, Translational/Peptide Chain Initiation, Translational/*drug effects

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Apr 28; Vol. 112 (17), pp. E2149-55. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

IL-27 confers a protumorigenic activity of regulatory T cells via CD39.

  • Authors : Park YJ; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, Seoul National University, 151-742 Seoul, Republic of Korea.; BK21 Plus Program, College of Pharmacy, Seoul National University, 151-742 Seoul, Korea.

Subjects: Antigens, CD/Antigens, CD/Antigens, CD/*genetics ; Apyrase/Apyrase/Apyrase/*genetics ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Feb 19; Vol. 116 (8), pp. 3106-3111. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation.

  • Authors : Bhattacharyya S; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. ; Zhao Y

Subjects: Glucocorticoids/Glucocorticoids/Glucocorticoids/*pharmacology ; Interferon-alpha/Interferon-alpha/Interferon-alpha/*metabolism ; Macrophages/Macrophages/Macrophages/*drug effects

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Jun 07; Vol. 108 (23), pp. 9554-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation.

  • Authors : Tahk S; Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.; Liu B

Subjects: Down-Regulation/Down-Regulation/Down-Regulation/*genetics ; NF-kappa B/NF-kappa B/NF-kappa B/*genetics ; NF-kappa B/NF-kappa B/NF-kappa B/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Jul 10; Vol. 104 (28), pp. 11643-8. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

  • Authors : Ramsauer K; Max F. Perutz Laboratories, Department of Microbiology and Immunobiology, University of Vienna, A1030 Vienna, Austria.; Farlik M

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*genetics ; Interferon Regulatory Factor-1/Interferon Regulatory Factor-1/Interferon Regulatory Factor-1/*metabolism ; Interferon-gamma/Interferon-gamma/Interferon-gamma/*pharmacology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Feb 20; Vol. 104 (8), pp. 2849-54. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells.

  • Authors : Wan CK; Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1674;

Subjects: CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*cytology ; Interleukins/Interleukins/Interleukins/*immunology ; STAT1 Transcription Factor/STAT1 Transcription Factor/STAT1 Transcription Factor/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Jul 28; Vol. 112 (30), pp. 9394-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.

  • Authors : Turnquist C; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine and.; Wang Y

Subjects: Cell Polarity*; Encephalitis/Encephalitis/Encephalitis/*physiopathology ; Neoplasms, Experimental/Neoplasms, Experimental/Neoplasms, Experimental/*prevention & control

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Jul 08; Vol. 111 (27), pp. 9834-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation.

  • Authors : Lu B; The Elmezzi Graduate School of Molecular Medicine, North Shore-LIJ Health System, Manhasset, NY 11030.; Antoine DJ

Subjects: Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; HMGB1 Protein/HMGB1 Protein/HMGB1 Protein/*metabolism ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Feb 25; Vol. 111 (8), pp. 3068-73. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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