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Academic Journal

An IL-23-STAT4 pathway is required for the proinflammatory function of classical dendritic cells during CNS inflammation.

Subjects: *DENDRITIC cells; *STAT proteins; *CENTRAL nervous system

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 8/6/2024, Vol. 121 Issue 32, p1-10. 10p.

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Academic Journal

Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses.

Subjects: *STAT proteins; *INFLAMMATION; *PHOSPHORYLATION

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 4/23/2024, Vol. 121 Issue 17, p1-12. 39p.

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Academic Journal

Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation.

Subjects: *KILLER cells; *STAT proteins; *INNATE lymphoid cells

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 10/3/2023, Vol. 120 Issue 40, p1-10. 20p.

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Academic Journal

pSTAT3 activation of Foxl2 initiates the female pathway underlying temperature-dependent sex determination.

Subjects: TEMPERATURE-dependent sex determination; SEX reversal; TESTIS development

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 9/10/2024, Vol. 121 Issue 37, p1-8, 23p

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Academic Journal

STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage.

Subjects: *DNA repair; *STAT proteins; *STIMULUS & response (Psychology)

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 4/18/2023, Vol. 120 Issue 16, Following p1-7. 25p.

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Academic Journal

IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+ through the noncanonical STAT3 pathway.

Subjects: *CELL motility; *STAT proteins; *INTERLEUKIN-6

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 9/14/2021, Vol. 118 Issue 37, p1-10. 10p.

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Academic Journal

Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.

Subjects: *STAT proteins; *GRANULOCYTE-macrophage colony-stimulating factor; *T helper cells

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 12/28/2021, Vol. 118 Issue 52, p1-11. 11p.

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Academic Journal

JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors.

Subjects: *MACROPHAGES; *STAT proteins; *TUMOR necrosis factors

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 6/18/2019, Vol. 116 Issue 25, p12442-12451. 10p.

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Academic Journal

FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitisassociated carcinogenesis.

Subjects: *CARCINOGENESIS; *STAT proteins; *INTERLEUKIN-6

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 5/21/2019, Vol. 116 Issue 21, p10447-10452. 6p.

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