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Academic Journal

Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition.

  • Authors : Sakuma I; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520.; Department of Molecular Diagnosis, Graduate School of Medicine Chiba University, Chiba 260-8670, Japan.

Subjects: Lipodystrophy*/Lipodystrophy*/Lipodystrophy*/genetics ; Fatty Liver* ; Overnutrition*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Dec 26; Vol. 120 (52), pp. e2312666120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

DIDO is necessary for the adipogenesis that promotes diet-induced obesity.

  • Authors : García-López MÁ; Department of Immunology and Oncology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas Campus, Universidad Autónoma de Madrid, Madrid 28049, Spain.; Mora A

Subjects: Adipogenesis*/Adipogenesis*/Adipogenesis*/genetics ; Lipodystrophy*; Animals

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jan 16; Vol. 121 (3), pp. e2300096121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Leptin treatment has vasculo-protective effects in lipodystrophic mice.

  • Authors : Stürzebecher PE; Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Leipzig, 04103, Germany.; Kralisch S

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/drug effects ; Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/drug effects ; Growth Differentiation Factor 15*/Growth Differentiation Factor 15*/Growth Differentiation Factor 15*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Oct 04; Vol. 119 (40), pp. e2110374119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome.

  • Authors : Zhang Z; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; .

Subjects: Adipocytes/Adipocytes/Adipocytes/*metabolism ; Insulin Resistance/Insulin Resistance/Insulin Resistance/*physiology ; Lipodystrophy/Lipodystrophy/Lipodystrophy/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 26; Vol. 117 (21), pp. 11829-11835. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Adipose tissue is a critical regulator of osteoarthritis.

  • Authors : Collins KH; Department of Orthopaedic Surgery, Washington University, St. Louis, MO 63110.; Shriners Hospitals for Children, St. Louis, MO 63110.

Subjects: Adipose Tissue/Adipose Tissue/Adipose Tissue/*metabolism ; Lipodystrophy/Lipodystrophy/Lipodystrophy/*metabolism ; Osteoarthritis, Knee/Osteoarthritis, Knee/Osteoarthritis, Knee/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease.

  • Authors : Payne F; Metabolic Disease Group, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, United Kingdom;

Subjects: Choline-Phosphate Cytidylyltransferase/Choline-Phosphate Cytidylyltransferase/Choline-Phosphate Cytidylyltransferase/*genetics ; Fatty Liver/Fatty Liver/Fatty Liver/*genetics ; Lipodystrophy/Lipodystrophy/Lipodystrophy/*congenital

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Jun 17; Vol. 111 (24), pp. 8901-6. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A mouse model of conditional lipodystrophy.

  • Authors : Kim S; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.; Huang LW

Subjects: Disease Models, Animal* ; Mice, Transgenic*; Lipodystrophy/Lipodystrophy/Lipodystrophy/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Oct 16; Vol. 104 (42), pp. 16627-32. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice.

  • Authors : Koutnikova H; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique/Institut National de la Santé et de la Recherche Médicale/Université Louis Pasteur, 67404 Illkirch, France.; Cock TA

Subjects: Adipose Tissue/Adipose Tissue/Adipose Tissue/*metabolism ; Lipodystrophy/Lipodystrophy/Lipodystrophy/*metabolism ; Muscles/Muscles/Muscles/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2003 Nov 25; Vol. 100 (24), pp. 14457-62. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology.

  • Authors : Szymanski KM; Department of Pharmacology, University of Texas Southwestern Medical School, Dallas, TX 75390, USA.; Binns D

Subjects: Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*metabolism ; GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/GTP-Binding Protein gamma Subunits/*biosynthesis ; Heterotrimeric GTP-Binding Proteins/Heterotrimeric GTP-Binding Proteins/Heterotrimeric GTP-Binding Proteins/*biosynthesis

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Dec 26; Vol. 104 (52), pp. 20890-5. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Inflammation and adipose tissue macrophages in lipodystrophic mice.

  • Authors : Herrero L; Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.; Shapiro H

Subjects: Lipodystrophy*/Lipodystrophy*/Lipodystrophy*/immunology ; Lipodystrophy*/Lipodystrophy*/Lipodystrophy*/pathology; Adipose Tissue/Adipose Tissue/Adipose Tissue/*cytology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Jan 05; Vol. 107 (1), pp. 240-5. Date of Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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