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Publication : proceedings of the national academy of sciences of the united states of america
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Academic Journal

ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation.

  • Authors : Liu X; Department of Immunology, Sun Yat-sen University Zhongshan School of Medicine, Guangzhou 510080, China.; Li X

Subjects: Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/genetics ; Genes, ras* ; Smad3 Protein*/Smad3 Protein*/Smad3 Protein*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jan 17; Vol. 120 (3), pp. e2208927120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Ablation of insulin receptor substrates 1 and 2 suppresses Kras -driven lung tumorigenesis.

  • Authors : Xu H; Center for Basic and Translational Obesity Research, Division of Endocrinology, Boston Children's Hospital, Boston, MA 02115.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115.

Subjects: Genes, ras*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*prevention & control

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Apr 17; Vol. 115 (16), pp. 4228-4233. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous.

  • Authors : Chung WJ; Bioinformatics & Computational Biology, Genentech, Inc., South San Francisco, CA 94080.; Daemen A

Subjects: Genes, ras* ; Genetic Heterogeneity*; Neoplasms/Neoplasms/Neoplasms/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Dec 19; Vol. 114 (51), pp. E10947-E10955. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.

  • Authors : McFadden DG; David H. Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA 02139; .

Subjects: Genes, myc* ; Genes, ras* ; Mutation*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Oct 18; Vol. 113 (42), pp. E6409-E6417. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia.

  • Authors : Oshima K; Institute for Cancer Genetics, Columbia University, New York, NY 10032.; Khiabanian H

Subjects: Genes, ras*; Clonal Evolution/Clonal Evolution/Clonal Evolution/*genetics ; Mutation/Mutation/Mutation/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Oct 04; Vol. 113 (40), pp. 11306-11311. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.

  • Authors : Mazhab-Jafari MT; Department of Medical Biophysics, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada M5G 2M9;

Subjects: Genes, ras* ; Mutation*; Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/Proto-Oncogene Proteins p21(ras)/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 May 26; Vol. 112 (21), pp. 6625-30. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif.

  • Authors : Tsai FD; New York University Perlmutter Cancer Institute, New York University School of Medicine, New York, NY 10016;

Subjects: Genes, ras* ; RNA Splicing*; Neoplasms/Neoplasms/Neoplasms/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Jan 20; Vol. 112 (3), pp. 779-84. Date ofPublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.

  • Authors : Rushworth LK; Cancer Research-UK Stress Response Laboratory, Division of Cancer Research, Medical Research Institute, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom;

Subjects: Genes, ras*; Cell Nucleus/Cell Nucleus/Cell Nucleus/*enzymology ; Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Dec 23; Vol. 111 (51), pp. 18267-72. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

K-RasV14I recapitulates Noonan syndrome in mice.

Subjects: Disease Models, Animal* ; Genes, ras* ; Mice, Mutant Strains*/Mice, Mutant Strains*/Mice, Mutant Strains*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Nov 18; Vol. 111 (46), pp. 16395-400. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.

Subjects: Genes, ras*; Acetamides/Acetamides/Acetamides/*chemistry ; Guanosine Diphosphate/Guanosine Diphosphate/Guanosine Diphosphate/*analogs & derivatives

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Jun 17; Vol. 111 (24), pp. 8895-900. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  328 results for ""Genes, ras""