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Publication : proceedings of the national academy of sciences of the united states of america
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Academic Journal

Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2.

  • Authors : Leonard B; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA 94080.; Sankar K

Subjects: Antibody Affinity* ; Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/chemistry ; Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jun 07; Vol. 119 (23), pp. e2201562119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Joined at the hip: The role of light chain complementarity determining region 2 in antibody self-association.

  • Authors : Sargunas PR; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218.; Spangler JB

Subjects: Antibodies*/Antibodies*/Antibodies*/chemistry ; Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/chemistry ; Immunoglobulin Light Chains*/Immunoglobulin Light Chains*/Immunoglobulin Light Chains*/chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jul 12; Vol. 119 (28), pp. e2208330119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions.

  • Authors : Bozhanova NG; Department of Chemistry, Vanderbilt University, Nashville, TN 37235.; Center for Structural Biology, Vanderbilt University, Nashville, TN 37235.

Subjects: Antibodies, Viral/Antibodies, Viral/Antibodies, Viral/*genetics ; Complementarity Determining Regions/Complementarity Determining Regions/Complementarity Determining Regions/*genetics ; Marburg Virus Disease/Marburg Virus Disease/Marburg Virus Disease/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 08; Vol. 117 (49), pp. 31142-31148. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naïve CD4 + T cells.

  • Authors : Logunova NN; Laboratory for Immunogenetics, Central Institute for Tuberculosis, Moscow, 107564, Russia.; Kriukova VV

Subjects: Complementarity Determining Regions/Complementarity Determining Regions/Complementarity Determining Regions/*immunology ; Histocompatibility Antigens Class II/Histocompatibility Antigens Class II/Histocompatibility Antigens Class II/*immunology ; Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/Receptors, Antigen, T-Cell/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 16; Vol. 117 (24), pp. 13659-13669. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.

  • Authors : Chan DTY; Cancer Research UK-AstraZeneca Antibody Alliance Laboratory, CB21 6GP Cambridge, United Kingdom.; Jenkinson L

Subjects: Antibody Affinity*; Antibodies/Antibodies/Antibodies/*chemistry ; Arginase/Arginase/Arginase/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 21; Vol. 117 (29), pp. 16949-16960. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Five computational developability guidelines for therapeutic antibody profiling.

  • Authors : Raybould MIJ; Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.; Marks C

Subjects: Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/chemistry ; Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/genetics ; Computer Simulation*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Mar 05; Vol. 116 (10), pp. 4025-4030. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Intrinsic physicochemical profile of marketed antibody-based biotherapeutics.

  • Authors : Ahmed L; Biotherapeutics Discovery, Boehringer Ingelheim, Ridgefield, CT 06877.; Gupta P

Subjects: Drug Design* ; Drug Discovery*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 14; Vol. 118 (37).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Restricting nonclassical MHC genes coevolve with TRAV genes used by innate-like T cells in mammals.

  • Authors : Boudinot P; Virologie et Immunologie Moléculaires (VIM), Institut National de la Recherche Agronomique (INRA), Université Paris-Saclay, 78352 Jouy-en-Josas, France; .

Subjects: Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/genetics ; Complementarity Determining Regions*/Complementarity Determining Regions*/Complementarity Determining Regions*/immunology ; Evolution, Molecular*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 May 24; Vol. 113 (21), pp. E2983-92. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization.

  • Authors : Willis JR; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232

Subjects: Antibodies, Neutralizing*/Antibodies, Neutralizing*/Antibodies, Neutralizing*/genetics ; Antibodies, Neutralizing*/Antibodies, Neutralizing*/Antibodies, Neutralizing*/immunology ; Complementarity Determining Regions*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Apr 19; Vol. 113 (16), pp. 4446-51. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.

  • Authors : Townsend S; Global Biotherapeutics Technologies, Pfizer Biotherapeutics R&D, Dublin D22, Ireland;

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*immunology ; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*therapeutic use ; Complementarity Determining Regions/Complementarity Determining Regions/Complementarity Determining Regions/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Dec 15; Vol. 112 (50), pp. 15354-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  294 results for ""Complementarity Determining Regions""