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Academic Journal

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy.

  • Authors : Seifinejad A; Department of Biomedical Sciences, Faculty of Biology and Medicine, University of Lausanne, 1005, Lausanne, Switzerland.; Ramosaj M

Subjects: Cataplexy*/Cataplexy*/Cataplexy*/genetics ; Neuropeptides*/Neuropeptides*/Neuropeptides*/metabolism ; Narcolepsy*/Narcolepsy*/Narcolepsy*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 09; Vol. 120 (19), pp. e2220911120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy.

  • Authors : Ito H; Department of Neuroscience II, Research Institute of Environmental Medicine, Nagoya University, Nagoya 464-8601, Japan.; Department of Neural Regulation, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

Subjects: Cataplexy* ; Narcolepsy* ; Orexins*/Orexins*/Orexins*/deficiency

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Oct 10; Vol. 120 (41), pp. e2301951120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.

  • Authors : Irukayama-Tomobe Y; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.; Ogawa Y

Subjects: Aniline Compounds/Aniline Compounds/Aniline Compounds/*pharmacology ; Benzamides/Benzamides/Benzamides/*pharmacology ; Cataplexy/Cataplexy/Cataplexy/*drug therapy

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 May 30; Vol. 114 (22), pp. 5731-5736. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.

  • Authors : Mieda M; Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9050, USA.; Willie JT

Subjects: Intracellular Signaling Peptides and Proteins*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*genetics ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*therapeutic use

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2004 Mar 30; Vol. 101 (13), pp. 4649-54. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy.

  • Authors : Nishino S; Sleep Disorders Center, Stanford University School of Medicine, Palo Alto, CA 94304.; Mignot E

Subjects: Cataplexy/Cataplexy/Cataplexy/*physiopathology ; Dinoprostone/Dinoprostone/Dinoprostone/*analogs & derivatives ; Dinoprostone/Dinoprostone/Dinoprostone/*therapeutic use

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1989 Apr; Vol. 86 (7), pp. 2483-7.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy.

Subjects: RAPID eye movement sleep; NARCOLEPSY; SLEEP

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 10/10/2023, Vol. 120 Issue 41, p1-12, 53p

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Academic Journal

Continuous intrathecal orexin delivery inhibits cataplexy in a murine model of narcolepsy.

Subjects: NARCOLEPSY; OREXINS; CATAPLEXY

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 6/5/2018, Vol. 115 Issue 23, p6046-6051, 6p

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Academic Journal

Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.

Subjects: NARCOLEPSY; OREXINS; CATAPLEXY

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 5/30/2017, Vol. 114 Issue 22, p5731-5736, 6p

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Academic Journal

Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity.

Subjects: NARCOLEPSY; OREXINS; AMYGDALOID body

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 4/25/2017, Vol. 114 Issue 17, pE3526-E3535, 10p, 6 Graphs

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Academic Journal

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice.

Subjects: T cells; NARCOLEPSY; CATAPLEXY

  • Source: Proceedings of the National Academy of Sciences of the United States of America; 9/27/2016, Vol. 113 Issue 39, p10956-10961, 6p

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