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Agricola

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Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform.

• Authors : Wang JKT; Cogent Neuroscience, Inc., Durham, NC 27704.; Portbury S

Subjects: Brain Ischemia/Brain Ischemia/Brain Ischemia/*pathology ; Brain Ischemia/Brain Ischemia/Brain Ischemia/*prevention & control ; Cardiac Glycosides/Cardiac Glycosides/Cardiac Glycosides/*pharmacology

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2006 Jul 05; Vol. 103 (27), pp. 10461-10466. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization.

• Authors : Langenhan JM; Laboratory for Biosynthetic Chemistry, Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA.; Peters NR

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemistry ; Cardiac Glycosides/Cardiac Glycosides/Cardiac Glycosides/*chemistry; Animals

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2005 Aug 30; Vol. 102 (35), pp. 12305-10. DatePublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor.

• Authors : Yang Q; Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Huang W

Subjects: Digitoxin/Digitoxin/Digitoxin/*pharmacology ; NF-kappa B/NF-kappa B/NF-kappa B/*metabolism ; Receptors, Tumor Necrosis Factor, Type I/Receptors, Tumor Necrosis Factor, Type I/Receptors, Tumor Necrosis Factor, Type I/*metabolism

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2005 Jul 05; Vol. 102 (27), pp. 9631-6. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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Structural insights into the binding of cardiac glycosides to the digitalis receptor revealed by solid-state NMR.

• Authors : Middleton DA; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom. ; Rankin S

Subjects: Cardiac Glycosides/Cardiac Glycosides/Cardiac Glycosides/*metabolism ; Sodium-Potassium-Exchanging ATPase/Sodium-Potassium-Exchanging ATPase/Sodium-Potassium-Exchanging ATPase/*metabolism; Carbohydrate Conformation

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2000 Dec 05; Vol. 97 (25), pp. 13602-7.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN:

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Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth.

• Authors : Huafeng Zhang; Qian, David Z.; Yee Sun Tan

Subjects: CARDIAC glycosides; TUMOR growth; CANCER treatment

• Source: Proceedings of the National Academy of Sciences of the United States of America; 12/16/2008, Vol. 105 Issue 50, p19579-19586, 8p, 2 Black and White Photographs, 6 Graphs

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Cardiac glycosides inhibit TNF-α/NF-κB signaling by blocking recruitment of TN F receptor-associated death domain to the TNF receptor.

• Authors : Qingfeng Yang; Wei Huang; Jozwik, Catherine

Subjects: CARDIAC glycosides; GLYCOSIDES; CARDIOTONIC agents

• Source: Proceedings of the National Academy of Sciences of the United States of America; 7/5/2005, Vol. 102 Issue 27, p9631-9636, 6p

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