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Academic Journal

The mechanism of allosteric regulation of calcium-independent phospholipase A 2 by ATP and calmodulin binding to the ankyrin domain.

  • Authors : Mouchlis VD; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0601.; Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA 92093-0601.

Subjects: Adenosine Triphosphate*/Adenosine Triphosphate*/Adenosine Triphosphate*/metabolism ; Calmodulin*/Calmodulin*/Calmodulin*/metabolism ; Calcium*/Calcium*/Calcium*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 26; Vol. 121 (48), pp. e2411539121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin.

  • Authors : Piserchio A; Department of Chemistry and Biochemistry, The City College of New York, New York, NY 10031.; Long KJ

Subjects: Elongation Factor 2 Kinase*/Elongation Factor 2 Kinase*/Elongation Factor 2 Kinase*/metabolism ; Calmodulin*/Calmodulin*/Calmodulin*/metabolism; Allosteric Regulation

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Apr 25; Vol. 120 (17), pp. e2300902120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Atomistic mechanisms of the regulation of small-conductance Ca 2+ -activated K + channel (SK2) by PIP2.

  • Authors : Woltz RL; Department of Internal Medicine, Division of Cardiovascular Medicine, University of California, Davis, CA 95616.; Zheng Y

Subjects: Phosphatidylinositol 4,5-Diphosphate*/Phosphatidylinositol 4,5-Diphosphate*/Phosphatidylinositol 4,5-Diphosphate*/metabolism ; Small-Conductance Calcium-Activated Potassium Channels*/Small-Conductance Calcium-Activated Potassium Channels*/Small-Conductance Calcium-Activated Potassium Channels*/metabolism ; Small-Conductance Calcium-Activated Potassium Channels*/Small-Conductance Calcium-Activated Potassium Channels*/Small-Conductance Calcium-Activated Potassium Channels*/chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 24; Vol. 121 (39), pp. e2318900121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Reversing anxiety by targeting a stress-responsive signaling pathway.

  • Authors : Pandey S; Synapse and Neural Circuit Research Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892.; Han W

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Anxiety*/Anxiety*/Anxiety*/drug therapy ; Anxiety*/Anxiety*/Anxiety*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 30; Vol. 121 (31), pp. e2400078121. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel.

  • Authors : Barret DCA; Laboratory of Biomolecular Research, Paul Scherrer Institute, 5232 Villigen, Switzerland.; Schuster D

Subjects: Cyclic Nucleotide-Gated Cation Channels*/Cyclic Nucleotide-Gated Cation Channels*/Cyclic Nucleotide-Gated Cation Channels*/genetics ; Cyclic Nucleotide-Gated Cation Channels*/Cyclic Nucleotide-Gated Cation Channels*/Cyclic Nucleotide-Gated Cation Channels*/metabolism ; Calmodulin*/Calmodulin*/Calmodulin*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Apr 11; Vol. 120 (15), pp. e2300309120. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Time-resolved DEER EPR and solid-state NMR afford kinetic and structural elucidation of substrate binding to Ca 2+ -ligated calmodulin.

  • Authors : Schmidt T; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892-0520.; Jeon J

Subjects: Calcium/Calcium/Calcium/*chemistry ; Calmodulin/Calmodulin/Calmodulin/*chemistry; Calcium/Calcium/Calcium/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Feb 08; Vol. 119 (6).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs.

  • Authors : Chamberlain SG; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom.; Gohlke A

Subjects: Calmodulin/Calmodulin/Calmodulin/*metabolism ; Lipid Bilayers/Lipid Bilayers/Lipid Bilayers/*metabolism ; ral GTP-Binding Proteins/ral GTP-Binding Proteins/ral GTP-Binding Proteins/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 07; Vol. 118 (36).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Elementary mechanisms of calmodulin regulation of Na V 1.5 producing divergent arrhythmogenic phenotypes.

  • Authors : Kang PW; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218; .

Subjects: Action Potentials/Action Potentials/Action Potentials/*genetics ; Calcium/Calcium/Calcium/*metabolism ; Calmodulin/Calmodulin/Calmodulin/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 May 25; Vol. 118 (21).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Synaptic memory survives molecular turnover.

  • Authors : Lee J; Department of Cellular and Molecular Pharmacology, University of California at San Francisco, San Francisco, CA 94158.; Chen X

Subjects: Calcium-Calmodulin-Dependent Protein Kinase Type 2*/Calcium-Calmodulin-Dependent Protein Kinase Type 2*/Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism ; Calmodulin*/Calmodulin*/Calmodulin*/metabolism; Hippocampus/Hippocampus/Hippocampus/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Oct 18; Vol. 119 (42), pp. e2211572119. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Assemblies of calcium/calmodulin-dependent kinase II with actin and their dynamic regulation by calmodulin in dendritic spines.

  • Authors : Wang Q; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.; Chen M

Subjects: Actins/Actins/Actins/*metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism ; Calmodulin/Calmodulin/Calmodulin/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Sep 17; Vol. 116 (38), pp. 18937-18942. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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