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Academic Journal

Tuning environmental timescales to evolve and maintain generalists.

  • Authors : Sachdeva V; Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL 60627.; Husain K

Subjects: Environment* ; Evolution, Molecular* ; Models, Genetic*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 09; Vol. 117 (23), pp. 12693-12699. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.

  • Authors : Raman S; Program in Molecular Medicine, Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.; Oncology Group, Northern Biologics, Toronto, ON M5G 1L7, Canada.

Subjects: Antibody Specificity*/Antibody Specificity*/Antibody Specificity*/genetics ; Antibody Specificity*/Antibody Specificity*/Antibody Specificity*/immunology ; Antineoplastic Agents, Immunological*/Antineoplastic Agents, Immunological*/Antineoplastic Agents, Immunological*/immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Apr 02; Vol. 116 (14), pp. 6812-6817. Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.

  • Authors : Wang F; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.; Sen S

Subjects: Antibodies, Monoclonal, Murine-Derived/Antibodies, Monoclonal, Murine-Derived/Antibodies, Monoclonal, Murine-Derived/*immunology ; Antibody Affinity/Antibody Affinity/Antibody Affinity/*physiology ; Antibody Specificity/Antibody Specificity/Antibody Specificity/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Mar 12; Vol. 110 (11), pp. 4261-6. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Particle shape enhances specificity of antibody-displaying nanoparticles.

  • Authors : Barua S; Department of Chemical Engineering, Center for Bioengineering, University of California, Santa Barbara, CA 93106, USA.; Yoo JW

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*immunology ; Antibody Specificity/Antibody Specificity/Antibody Specificity/*immunology ; Nanoparticles/Nanoparticles/Nanoparticles/*chemistry

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Feb 26; Vol. 110 (9), pp. 3270-5. Date ofPublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody.

  • Authors : Tudor D; Mucosal Entry of HIV-1 and Mucosal Immunity, Cell Biology and Host-Pathogen Interactions Department, Cochin Institute, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, 75014 Paris, France.; Yu H

Subjects: Antibody Specificity*; Acquired Immunodeficiency Syndrome/Acquired Immunodeficiency Syndrome/Acquired Immunodeficiency Syndrome/*immunology ; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Jul 31; Vol. 109 (31), pp. 12680-5. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Immunoglobulin isotype influences affinity and specificity.

  • Authors : Casadevall A; Division of Infectious Diseases, Department of Microbiology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. ; Janda A

Subjects: Antibody Specificity*; Acquired Immunodeficiency Syndrome/Acquired Immunodeficiency Syndrome/Acquired Immunodeficiency Syndrome/*immunology ; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Jul 31; Vol. 109 (31), pp. 12272-3. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies.

  • Authors : Hu X; Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.; Kang S

Subjects: Antibody Specificity* ; Peptide Library*; Epitopes/Epitopes/Epitopes/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Apr 06; Vol. 107 (14), pp. 6252-7. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions.

  • Authors : Joyce JG; Department of Vaccines Basic Research, Merck Research Laboratories, 770 Sumneytown Pike, West Point, PA 19486, USA. ; Krauss IJ

Subjects: Antibody Specificity*; Antibodies/Antibodies/Antibodies/*immunology ; Glycopeptides/Glycopeptides/Glycopeptides/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Oct 14; Vol. 105 (41), pp. 15684-9. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structure and specificity of lamprey monoclonal antibodies.

  • Authors : Herrin BR; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Alder MN

Subjects: Antibody Specificity*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*immunology; Amino Acid Sequence

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2008 Feb 12; Vol. 105 (6), pp. 2040-5. Date ofPublisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition.

  • Authors : James LC; Laboratory of Molecular Biology, Medical Research Council, Cambridge CB2 2HQ, United Kingdom. ; Tawfik DS

Subjects: Antibody Specificity*; Antigens/Antigens/Antigens/*chemistry ; Antigens/Antigens/Antigens/*immunology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2005 Sep 06; Vol. 102 (36), pp. 12730-5. Date Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Print

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