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HIF-1α is essential for effective PMN bacterial killing, antimicrobial peptide production and apoptosis in Pseudomonas aeruginosa keratitis.

• Authors : Berger EA; Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America.; McClellan SA

Subjects: Cytotoxicity, Immunologic*/Cytotoxicity, Immunologic*/Cytotoxicity, Immunologic*/drug effects; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*biosynthesis ; Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism

• Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (7), pp. e1003457. Date of Electronic Publication: 2013 Jul 18.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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