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Academic Journal

Actives from MMV Open Access Boxes? A suggested way forward.

  • Authors : Samby K; Medicines for Malaria Venture, Geneva, Switzerland.; Willis PA

Subjects: Drug Discovery* ; Validation Studies as Topic*; Malaria/Malaria/Malaria/*drug therapy

  • Source: PLoS pathogens [PLoS Pathog] 2021 Apr 22; Vol. 17 (4), pp. e1009384. Date of Electronic Publication: 2021 Apr 22 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.

  • Authors : Murgolo N; Department of Genetics and Pharmacogenomics, Merck & Co., Inc., Kenilworth, New Jersey, United States of America.; Therien AG

Subjects: Drug Discovery* ; Viral Tropism* ; Virus Internalization*

  • Source: PLoS pathogens [PLoS Pathog] 2021 Feb 17; Vol. 17 (2), pp. e1009225. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.

  • Authors : Yogavel M; Molecular Medicine-Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, India.; Bougdour A

Subjects: Toxoplasma*/Toxoplasma*/Toxoplasma*/genetics ; Amino Acyl-tRNA Synthetases*/Amino Acyl-tRNA Synthetases*/Amino Acyl-tRNA Synthetases*/genetics ; Toxoplasmosis*

  • Source: PLoS pathogens [PLoS Pathog] 2023 Feb 28; Vol. 19 (2), pp. e1011124. Date of Electronic Publication: 2023 Feb 28 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells.

  • Authors : Pickard A; Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom.; School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

Subjects: Drug Repositioning* ; COVID-19 Drug Treatment*; Drug Discovery/Drug Discovery/Drug Discovery/*methods

  • Source: PLoS pathogens [PLoS Pathog] 2021 Sep 09; Vol. 17 (9), pp. e1009840. Date of Electronic Publication: 2021 Sep 09 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.

  • Authors : Verkoczy L; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America

Subjects: Drug Discovery*/Drug Discovery*/Drug Discovery*/methods ; Drug Discovery*/Drug Discovery*/Drug Discovery*/standards; AIDS Vaccines/AIDS Vaccines/AIDS Vaccines/*therapeutic use

  • Source: PLoS pathogens [PLoS Pathog] 2014 May 22; Vol. 10 (5), pp. e1004073. Date of Electronic Publication: 2014 May 22 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity.

  • Authors : Starkey M; Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America

Subjects: Drug Discovery*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Drug Resistance, Bacterial/Drug Resistance, Bacterial/Drug Resistance, Bacterial/*drug effects

  • Source: PLoS pathogens [PLoS Pathog] 2014 Aug 21; Vol. 10 (8), pp. e1004321. Date of Electronic Publication: 2014 Aug 21 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Putting fungi to work: harvesting a cornucopia of drugs, toxins, and antibiotics.

  • Authors : Kück U; Christian Doppler Laboratory for Fungal Biotechnology, Ruhr-Universität Bochum, Bochum, Germany; Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, Bochum, Germany.

Subjects: Drug Discovery* ; Fungi*/Fungi*/Fungi*/chemistry; Animals

  • Source: PLoS pathogens [PLoS Pathog] 2014 Mar 13; Vol. 10 (3), pp. e1003950. Date of Electronic Publication: 2014 Mar 13 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Report

Tuberculosis drug discovery in the CRISPR era.

  • Authors : Rock J; Laboratory of Host-Pathogen Biology, The Rockefeller University, New York, New York, United States of America.

Subjects: Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Tuberculosis/Tuberculosis/Tuberculosis/*drug therapy; Antitubercular Agents/Antitubercular Agents/Antitubercular Agents/therapeutic use

  • Source: PLoS pathogens [PLoS Pathog] 2019 Sep 19; Vol. 15 (9), pp. e1007975. Date of Electronic Publication: 2019 Sep 19 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Plasmodium falciparum contains functional SCF and CRL4 ubiquitin E3 ligases, and CRL4 is critical for cell division and membrane integrity.

Subjects: CELL division; PLASMODIUM falciparum; DRUG discovery

  • Source: PLoS Pathogens; 2/28/2024, Vol. 20 Issue 2, p1-43, 43p

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Academic Journal

Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways.

  • Authors : Taylor CM; The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Wang Q

Subjects: Databases, Protein* ; Drug Discovery* ; Helminth Proteins*/Helminth Proteins*/Helminth Proteins*/genetics

  • Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (8), pp. e1003505. Date of Electronic Publication: 2013 Aug 01.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  47 results for ""Drug Discovery""