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Academic Journal

A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host.

  • Authors : Chen J; Sino-French Hoffmann Institute, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.; Lin G

Subjects: Drosophila melanogaster*/Drosophila melanogaster*/Drosophila melanogaster*/microbiology ; Drosophila melanogaster*/Drosophila melanogaster*/Drosophila melanogaster*/immunology ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/pathogenicity

  • Source: PLoS pathogens [PLoS Pathog] 2024 Jun 04; Vol. 20 (6), pp. e1012252. Date of Electronic Publication: 2024 Jun 04 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm.

  • Authors : Rapsinski GJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United State of America.; Division of Infectious Disease, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

Subjects: Biofilms*/Biofilms*/Biofilms*/growth & development ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2024 May 31; Vol. 20 (5), pp. e1011453. Date of Electronic Publication: 2024 May 31 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress.

  • Authors : Song Y; College of Life Science, Sichuan Normal University, Chengdu, China.; Zhang S

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/metabolism ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/genetics ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/microbiology

  • Source: PLoS pathogens [PLoS Pathog] 2024 Jan 10; Vol. 20 (1), pp. e1011946. Date of Electronic Publication: 2024 Jan 10 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

  • Authors : Kumar N; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Wexner Medical Center, Columbus, Ohio, United States of America.; Pestrak MJ

Subjects: Pseudomonas Infections* ; Heart Diseases*; Animals

  • Source: PLoS pathogens [PLoS Pathog] 2023 Aug 25; Vol. 19 (8), pp. e1011573. Date of Electronic Publication: 2023 Aug 25 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A compensatory RNase E variation increases Iron Piracy and Virulence in multidrug-resistant Pseudomonas aeruginosa during Macrophage infection.

  • Authors : Vaillancourt M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.; Galdino ACM

Subjects: Iron*/Iron*/Iron*/metabolism ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2023 Apr 07; Vol. 19 (4), pp. e1010942. Date of Electronic Publication: 2023 Apr 07 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Current concepts on Pseudomonas aeruginosa interaction with human airway epithelium.

  • Authors : Muggeo A; Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, Laboratoire de bactériologie-Virologie-Hygiène hospitalière-Parasitologie-Mycologie, P3Cell, U 1250, Reims, France.; Coraux C

Subjects: Pseudomonas aeruginosa* ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/microbiology; Humans

  • Source: PLoS pathogens [PLoS Pathog] 2023 Mar 30; Vol. 19 (3), pp. e1011221. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The opportunistic pathogen Pseudomonas aeruginosa exploits bacterial biotin synthesis pathway to benefit its infectivity.

  • Authors : Shi Y; Department of Microbiology, and Department of General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Cao Q

Subjects: Biotin*/Biotin*/Biotin*/chemistry ; Biotin*/Biotin*/Biotin*/metabolism ; Pseudomonas Infections*

  • Source: PLoS pathogens [PLoS Pathog] 2023 Jan 23; Vol. 19 (1), pp. e1011110. Date of Electronic Publication: 2023 Jan 23 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.

  • Authors : Bagayoko S; Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, Toulouse, France.; Leon-Icaza SA

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Host-Pathogen Interactions/Host-Pathogen Interactions/Host-Pathogen Interactions/*physiology ; Lipid Peroxidation/Lipid Peroxidation/Lipid Peroxidation/*physiology

  • Source: PLoS pathogens [PLoS Pathog] 2021 Sep 13; Vol. 17 (9), pp. e1009927. Date of Electronic Publication: 2021 Sep 13 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Elucidating the mechanism by which synthetic helper peptides sensitize Pseudomonas aeruginosa to multiple antibiotics.

  • Authors : Xia Y; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, Netherlands.; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.

Subjects: Pseudomonas Infections*; Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*pharmacology ; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*pharmacology

  • Source: PLoS pathogens [PLoS Pathog] 2021 Sep 03; Vol. 17 (9), pp. e1009909. Date of Electronic Publication: 2021 Sep 03 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.

  • Authors : Qin W; Center of Experimental & Molecular Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Brands X

Subjects: DNA (Cytosine-5-)-Methyltransferases/DNA (Cytosine-5-)-Methyltransferases/DNA (Cytosine-5-)-Methyltransferases/*immunology ; Pneumonia, Bacterial/Pneumonia, Bacterial/Pneumonia, Bacterial/*immunology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2021 Apr 01; Vol. 17 (4), pp. e1009491. Date of Electronic Publication: 2021 Apr 01 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.

  • Authors : Renieris G; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece.; Droggiti DE

Subjects: Cystathionine gamma-Lyase/Cystathionine gamma-Lyase/Cystathionine gamma-Lyase/*metabolism ; Hydrogen Sulfide/Hydrogen Sulfide/Hydrogen Sulfide/*metabolism ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2021 Mar 26; Vol. 17 (3), pp. e1009473. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment.

  • Authors : Bartell JA; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.; Cameron DR

Subjects: Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*microbiology ; Host-Pathogen Interactions/Host-Pathogen Interactions/Host-Pathogen Interactions/*physiology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*microbiology

  • Source: PLoS pathogens [PLoS Pathog] 2020 Dec 14; Vol. 16 (12), pp. e1009112. Date of Electronic Publication: 2020 Dec 14 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance.

  • Authors : Maiden MM; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.; The BEACON Center for The Study of Evolution in Action, Michigan State University, East Lansing, Michigan, United States of America.

Subjects: Aminoglycosides/Aminoglycosides/Aminoglycosides/*pharmacology ; Biofilms/Biofilms/Biofilms/*drug effects ; Drug Resistance, Bacterial/Drug Resistance, Bacterial/Drug Resistance, Bacterial/*drug effects

  • Source: PLoS pathogens [PLoS Pathog] 2020 Oct 30; Vol. 16 (10), pp. e1008529. Date of Electronic Publication: 2020 Oct 30 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa.

  • Authors : Vrla GD; Department of Molecular Biology, Princeton University, Princeton, NJ, Unites States of America.; Esposito M

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/metabolism ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/pathogenicity; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2020 Sep 14; Vol. 16 (9), pp. e1008867. Date of Electronic Publication: 2020 Sep 14 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Patient genetics is linked to chronic wound microbiome composition and healing.

  • Authors : Tipton CD; Department of Biological Sciences, Texas Tech University, Lubbock, Texas, United States of America.; RTL Genomics, Lubbock, Texas, United States of America.

Subjects: Microbiota* ; Polymorphism, Single Nucleotide* ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/genetics

  • Source: PLoS pathogens [PLoS Pathog] 2020 Jun 18; Vol. 16 (6), pp. e1008511. Date of Electronic Publication: 2020 Jun 18 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics.

  • Authors : Crabbé A; Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.; Ostyn L

Subjects: Metabolome*; Culture Media, Conditioned/Culture Media, Conditioned/Culture Media, Conditioned/*pharmacology ; Lung/Lung/Lung/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2019 Apr 29; Vol. 15 (4), pp. e1007697. Date of Electronic Publication: 2019 Apr 29 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa.

  • Authors : McHugh BJ; Centre for Inflammation Research at the University of Edinburgh, Queens' Medical Research Institute, Edinburgh BioQuarter, Little France Crescent, Edinburgh, United Kingdom.; Wang R

Subjects: Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*pharmacology ; Cathelicidins/Cathelicidins/Cathelicidins/*pharmacology ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2019 Apr 12; Vol. 15 (4), pp. e1007694. Date of Electronic Publication: 2019 Apr 12 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.

  • Authors : Zhang Y; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.; Faucher F

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry ; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*growth & development ; Fimbriae, Bacterial/Fimbriae, Bacterial/Fimbriae, Bacterial/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2018 Oct 22; Vol. 14 (10), pp. e1007343. Date of Electronic Publication: 2018 Oct 22 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments.

  • Authors : Pestrak MJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America.; Chaney SB

Subjects: Host-Pathogen Interactions*; Neutrophils/Neutrophils/Neutrophils/*immunology ; Pneumonia, Bacterial/Pneumonia, Bacterial/Pneumonia, Bacterial/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2018 Feb 02; Vol. 14 (2), pp. e1006842. Date of Electronic Publication: 2018 Feb 02 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death.

  • Authors : Kroken AR; School of Optometry, University of California, Berkeley, Berkeley, California, United States of America.; Department of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, United States of America.

Subjects: Cell Membrane Permeability*; ADP Ribose Transferases/ADP Ribose Transferases/ADP Ribose Transferases/*metabolism ; Exotoxins/Exotoxins/Exotoxins/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2022 Feb 07; Vol. 18 (2), pp. e1010306. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Interleukin-36γ and IL-36 receptor signaling mediate impaired host immunity and lung injury in cytotoxic Pseudomonas aeruginosa pulmonary infection: Role of prostaglandin E2.

  • Authors : Aoyagi T; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Infection Control and Laboratory Diagnostics, Internal Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/immunology; Dinoprostone/Dinoprostone/Dinoprostone/*metabolism ; Immunity, Innate/Immunity, Innate/Immunity, Innate/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2017 Nov 22; Vol. 13 (11), pp. e1006737. Date of Electronic Publication: 2017 Nov 22 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Genome-wide association study of signature genetic alterations among pseudomonas aeruginosa cystic fibrosis isolates.

  • Authors : Hwang W; Department of Microbiology and Immunology, Seoul, Republic of Korea.; Brain Korea 21 PLUS Project for Medical Sciences, Seoul, Republic of Korea.

Subjects: Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*microbiology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*genetics ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*genetics

  • Source: PLoS pathogens [PLoS Pathog] 2021 Jun 23; Vol. 17 (6), pp. e1009681. Date of Electronic Publication: 2021 Jun 23 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection.

  • Authors : Lin T; Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Quellier D

Subjects: Disease Models, Animal*; Keratitis/Keratitis/Keratitis/*pathology ; Neutrophils/Neutrophils/Neutrophils/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2021 May 06; Vol. 17 (5), pp. e1009557. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles.

  • Authors : Koeppen K; Department of Microbiology and Immunology, The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Hampton TH

Subjects: Pseudomonas Infections*; Host-Pathogen Interactions/Host-Pathogen Interactions/Host-Pathogen Interactions/*physiology ; RNA, Small Interfering/RNA, Small Interfering/RNA, Small Interfering/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2016 Jun 13; Vol. 12 (6), pp. e1005672. Date of Electronic Publication: 2016 Jun 13 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

mir-233 modulates the unfolded protein response in C. elegans during Pseudomonas aeruginosa infection.

  • Authors : Dai LL; Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, Yunnan, China.; Gao JX

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/immunology ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2015 Jan 08; Vol. 11 (1), pp. e1004606. Date of Electronic Publication: 2015 Jan 08 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Pseudomonas aeruginosa type III translocon is required for biofilm formation at the epithelial barrier.

  • Authors : Tran CS; Department of Pediatrics, University of California San Francisco, San Francisco, California, United States of America.; Rangel SM

Subjects: Biofilms*; Bacterial Secretion Systems/Bacterial Secretion Systems/Bacterial Secretion Systems/*immunology ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2014 Nov 06; Vol. 10 (11), pp. e1004479. Date of Electronic Publication: 2014 Nov 06 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A live auxotrophic vaccine confers mucosal immunity and protection against lethal pneumonia caused by Pseudomonas aeruginosa.

  • Authors : Cabral MP; Department of Microbiology, University Hospital A Coruña (CHUAC)-Biomedical Research Institute A Coruña (INIBIC), A Coruña, Spain.; Correia A

Subjects: Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*immunology ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*immunology ; Vaccines, Attenuated/Vaccines, Attenuated/Vaccines, Attenuated/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2020 Feb 10; Vol. 16 (2), pp. e1008311. Date of Electronic Publication: 2020 Feb 10 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia.

  • Authors : Rangel SM; Departments of Microbiology/Immunology, Feinberg School of Medicine, Northwestern Univesity, Chicago, Illinois, United States of America.; Diaz MH

Subjects: ADP Ribose Transferases/ADP Ribose Transferases/ADP Ribose Transferases/*metabolism ; Bacteremia/Bacteremia/Bacteremia/*pathology ; Bacterial Toxins/Bacterial Toxins/Bacterial Toxins/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2015 Jun 19; Vol. 11 (6), pp. e1004945. Date of Electronic Publication: 2015 Jun 19 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells.

  • Authors : van 't Wout EF; Department of Pulmonology, Leiden University Medical Centre, Leiden, the Netherlands; Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, United Kingdom.

Subjects: Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Protein Phosphatase 1/Protein Phosphatase 1/Protein Phosphatase 1/*metabolism ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2015 Jun 17; Vol. 11 (6), pp. e1004946. Date of Electronic Publication: 2015 Jun 17 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Elucidation of sigma factor-associated networks in Pseudomonas aeruginosa reveals a modular architecture with limited and function-specific crosstalk.

  • Authors : Schulz S; Institute for Molecular Bacteriology, TWINCORE GmbH, Center for Clinical and Experimental Infection Research, a joint venture of the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany; Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

Subjects: Host-Parasite Interactions/Host-Parasite Interactions/Host-Parasite Interactions/*physiology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*genetics ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*physiology

  • Source: PLoS pathogens [PLoS Pathog] 2015 Mar 17; Vol. 11 (3), pp. e1004744. Date of Electronic Publication: 2015 Mar 17 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Involvement of a 1-Cys peroxiredoxin in bacterial virulence.

  • Authors : Kaihami GH; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.; Almeida JR

Subjects: Host-Pathogen Interactions/Host-Pathogen Interactions/Host-Pathogen Interactions/*immunology ; Macrophages/Macrophages/Macrophages/*immunology ; Peroxiredoxins/Peroxiredoxins/Peroxiredoxins/*pharmacology

  • Source: PLoS pathogens [PLoS Pathog] 2014 Oct 16; Vol. 10 (10), pp. e1004442. Date of Electronic Publication: 2014 Oct 16 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cationic antimicrobial peptides promote microbial mutagenesis and pathoadaptation in chronic infections.

  • Authors : Limoli DH; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America.; Rockel AB

Subjects: Adaptation, Physiological* ; Mutagenesis*; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2014 Apr 24; Vol. 10 (4), pp. e1004083. Date of Electronic Publication: 2014 Apr 24 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A novel signal transduction pathway that modulates rhl quorum sensing and bacterial virulence in Pseudomonas aeruginosa.

  • Authors : Cao Q; Hainan University, Haikou, Hainan, China; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Subjects: Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*metabolism ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*pathogenicity ; Quorum Sensing/Quorum Sensing/Quorum Sensing/*physiology

  • Source: PLoS pathogens [PLoS Pathog] 2014 Aug 28; Vol. 10 (8), pp. e1004340. Date of Electronic Publication: 2014 Aug 28 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.

  • Authors : LaBauve AE; Department of Microbiology and Molecular Genetics and The Vermont Lung Center, University of Vermont College of Medicine, Burlington, Vermont, United States of America.; Wargo MJ

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Lung/Lung/Lung/*microbiology ; Pneumonia, Bacterial/Pneumonia, Bacterial/Pneumonia, Bacterial/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2014 Jan; Vol. 10 (1), pp. e1003889. Date of Electronic Publication: 2014 Jan 23.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4.

  • Authors : Cohen TS; Department of Pediatrics, Columbia University, New York, New York, United States of America.; Prince AS

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*biosynthesis ; Cytokines/Cytokines/Cytokines/*metabolism ; Pneumonia, Staphylococcal/Pneumonia, Staphylococcal/Pneumonia, Staphylococcal/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (10), pp. e1003682. Date of Electronic Publication: 2013 Oct 03.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

HIF-1α is essential for effective PMN bacterial killing, antimicrobial peptide production and apoptosis in Pseudomonas aeruginosa keratitis.

  • Authors : Berger EA; Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America.; McClellan SA

Subjects: Cytotoxicity, Immunologic*/Cytotoxicity, Immunologic*/Cytotoxicity, Immunologic*/drug effects; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*biosynthesis ; Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (7), pp. e1003457. Date of Electronic Publication: 2013 Jul 18.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa pili and flagella mediate distinct binding and signaling events at the apical and basolateral surface of airway epithelium.

  • Authors : Bucior I; Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.; Pielage JF

Subjects: Adhesins, Bacterial/Adhesins, Bacterial/Adhesins, Bacterial/*immunology ; Bacterial Adhesion/Bacterial Adhesion/Bacterial Adhesion/*immunology ; Fimbriae, Bacterial/Fimbriae, Bacterial/Fimbriae, Bacterial/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (4), pp. e1002616. Date of Electronic Publication: 2012 Apr 05.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans.

  • Authors : Hoeven Rv; Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.; McCallum KC

Subjects: Enterococcus faecalis* ; Pseudomonas aeruginosa*; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2011 Dec; Vol. 7 (12), pp. e1002453. Date of Electronic Publication: 2011 Dec 22.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Positive signature-tagged mutagenesis in Pseudomonas aeruginosa: tracking patho-adaptive mutations promoting airways chronic infection.

  • Authors : Bianconi I; San Raffaele Scientific Institute, Division of Immunology, Transplantation and Infectious Diseases, Milano, Italy.; Milani A

Subjects: Adaptation, Biological/Adaptation, Biological/Adaptation, Biological/*genetics ; Mutagenesis/Mutagenesis/Mutagenesis/*physiology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*microbiology

  • Source: PLoS pathogens [PLoS Pathog] 2011 Feb 03; Vol. 7 (2), pp. e1001270. Date of Electronic Publication: 2011 Feb 03.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Host adaptation is contingent upon the infection route taken by pathogens.

Subjects: Immunity, Innate*; Adaptation, Physiological/Adaptation, Physiological/Adaptation, Physiological/*immunology ; Pseudomonas/Pseudomonas/Pseudomonas/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (9), pp. e1003601. Date of Electronic Publication: 2013 Sep 26.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Inhibition of macrophage migration inhibitory factor ameliorates ocular Pseudomonas aeruginosa-induced keratitis.

  • Authors : Gadjeva M; Department of Medicine, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America. ; Nagashima J

Subjects: Keratitis*/Keratitis*/Keratitis*/drug therapy ; Keratitis*/Keratitis*/Keratitis*/immunology ; Keratitis*/Keratitis*/Keratitis*/microbiology

  • Source: PLoS pathogens [PLoS Pathog] 2010 Mar 26; Vol. 6 (3), pp. e1000826. Date of Electronic Publication: 2010 Mar 26.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa.

  • Authors : Malone JG; Biozentrum, University of Basel, Basel, Switzerland. ; Jaeger T

Subjects: Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/*genetics ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*analogs & derivatives ; Periplasmic Proteins/Periplasmic Proteins/Periplasmic Proteins/*genetics

  • Source: PLoS pathogens [PLoS Pathog] 2010 Mar 12; Vol. 6 (3), pp. e1000804. Date of Electronic Publication: 2010 Mar 12.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Local inflammation induces complement crosstalk which amplifies the antimicrobial response.

  • Authors : Zhang J; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore.; Koh J

Subjects: Complement Pathway, Classical* ; Complement Pathway, Mannose-Binding Lectin*; C-Reactive Protein/C-Reactive Protein/C-Reactive Protein/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2009 Jan; Vol. 5 (1), pp. e1000282. Date of Electronic Publication: 2009 Jan 30.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways.

  • Authors : Malone JG; Biozentrum of the University of Basel, Basel, Switzerland.; Jaeger T

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics; Adaptation, Physiological/Adaptation, Physiological/Adaptation, Physiological/*physiology ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (6), pp. e1002760. Date of Electronic Publication: 2012 Jun 14.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity.

  • Authors : Luckett JC; School of Molecular Medical Sciences, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, United Kingdom.; Darch O

Subjects: Aminopeptidases/Aminopeptidases/Aminopeptidases/*metabolism ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (8), pp. e1002854. Date of Electronic Publication: 2012 Aug 23.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes.

  • Authors : Kesarwani M; Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Hazan R

Subjects: Acetophenones/Acetophenones/Acetophenones/*metabolism ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Gene Expression Regulation, Bacterial/Gene Expression Regulation, Bacterial/Gene Expression Regulation, Bacterial/*physiology

  • Source: PLoS pathogens [PLoS Pathog] 2011 Aug; Vol. 7 (8), pp. e1002192. Date of Electronic Publication: 2011 Aug 04.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus.

  • Authors : Irazoqui JE; Program of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America. ; Troemel ER

Subjects: Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*microbiology ; Pseudomonas Infections/Pseudomonas Infections/Pseudomonas Infections/*microbiology ; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/*pathogenicity

  • Source: PLoS pathogens [PLoS Pathog] 2010 Jul 01; Vol. 6, pp. e1000982. Date of Electronic Publication: 2010 Jul 01.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway.

  • Authors : Hoffman LR; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Richardson AR

Subjects: Adaptation, Physiological*; Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*microbiology ; Drug Resistance, Microbial/Drug Resistance, Microbial/Drug Resistance, Microbial/*genetics

  • Source: PLoS pathogens [PLoS Pathog] 2010 Jan 08; Vol. 6 (1), pp. e1000712. Date of Electronic Publication: 2010 Jan 08.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model.

  • Authors : Liehl P; Centre de Génétique Moléculaire, Centre National de la Rercheche Scientifique, Gif-sur-Yvette, France.; Blight M

Subjects: Antibodies, Bacterial/Antibodies, Bacterial/Antibodies, Bacterial/*biosynthesis ; Drosophila/Drosophila/Drosophila/*immunology ; Drosophila/Drosophila/Drosophila/*microbiology

  • Source: PLoS pathogens [PLoS Pathog] 2006 Jun; Vol. 2 (6), pp. e56. Date of Electronic Publication: 2006 Jun 09.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration.

  • Authors : Pazos MA; Mucosal Immunology & Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts, United States of America.; Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America.

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*immunology ; Leukotriene B4/Leukotriene B4/Leukotriene B4/*immunology ; Neutrophil Infiltration/Neutrophil Infiltration/Neutrophil Infiltration/*immunology

  • Source: PLoS pathogens [PLoS Pathog] 2017 Aug 03; Vol. 13 (8), pp. e1006548. Date of Electronic Publication: 2017 Aug 03 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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