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Academic Journal

Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.

  • Authors : Donovan KF; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.; Hegde M

Subjects: CRISPR-Cas Systems* ; Mutagenesis*; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*genetics

  • Source: PloS one [PLoS One] 2017 Jan 24; Vol. 12 (1), pp. e0170445. Date of Electronic Publication:Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Identification of Putative Mek1 Substrates during Meiosis in Saccharomyces cerevisiae Using Quantitative Phosphoproteomics.

  • Authors : Suhandynata RT; Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794-5215, United States of America.; Wan L

Subjects: Meiosis*; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*metabolism ; Phosphoproteins/Phosphoproteins/Phosphoproteins/*analysis

  • Source: PloS one [PLoS One] 2016 May 23; Vol. 11 (5), pp. e0155931. Date of Electronic Publication: 2016 May 23 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.

  • Authors : Bowles KR; Institute of Psychological Medicine and Clinical Neurosciences, MRC centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Hadyn Ellis building, Maindy Road, Cardiff University, Cardiff CF24 4HQ, Wales, United Kingdom.; Brooks SP

Subjects: Corpus Striatum/Corpus Striatum/Corpus Striatum/*metabolism ; Huntington Disease/Huntington Disease/Huntington Disease/*genetics ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*genetics

  • Source: PloS one [PLoS One] 2015 Dec 14; Vol. 10 (12), pp. e0144864. Date of Electronic Publication: 2015 Dec 14 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation.

  • Authors : Yang W; Pharmacy and Biological Science School, Weifang Medical University, Weifang, China.; Li Q

Subjects: Lysophospholipids/Lysophospholipids/Lysophospholipids/*pharmacology ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*genetics ; Matrix Metalloproteinase 2/Matrix Metalloproteinase 2/Matrix Metalloproteinase 2/*genetics

  • Source: PloS one [PLoS One] 2014 Sep 04; Vol. 9 (9), pp. e106725. Date of Electronic Publication: 2014 Sep 04 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo.

  • Authors : Zennadi R; Division of Hematology and Duke Comprehensive Sickle Cell Center, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.

Subjects: Anemia, Sickle Cell/Anemia, Sickle Cell/Anemia, Sickle Cell/*drug therapy ; Erythrocyte Aggregation/Erythrocyte Aggregation/Erythrocyte Aggregation/*drug effects ; Erythrocytes/Erythrocytes/Erythrocytes/*enzymology

  • Source: PloS one [PLoS One] 2014 Oct 20; Vol. 9 (10), pp. e110306. Date of Electronic Publication: 2014 Oct 20 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation.

  • Authors : Dave S; CSIR-Institute of Microbial Technology, Chandigarh, India.; Nanduri R

Subjects: Adipocytes/Adipocytes/Adipocytes/*cytology ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*physiology ; PPAR gamma/PPAR gamma/PPAR gamma/*metabolism

  • Source: PloS one [PLoS One] 2014 Jun 24; Vol. 9 (6), pp. e100862. Date of Electronic Publication: 2014 Jun 24 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Cotton GhMKK1 induces the tolerance of salt and drought stress, and mediates defence responses to pathogen infection in transgenic Nicotiana benthamiana.

  • Authors : Lu W; State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.; Chu X

Subjects: Gossypium/Gossypium/Gossypium/*genetics ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*genetics ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*metabolism

  • Source: PloS one [PLoS One] 2013 Jul 03; Vol. 8 (7), pp. e68503. Date of Electronic Publication: 2013 Jul 03 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet

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Academic Journal

SWAP-70: a new type of oncogene.

  • Authors : Shu CL; Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan, Republic of China.; Jing-Yang-Lai

Subjects: Gene Expression Regulation* ; Signal Transduction*; Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*genetics

  • Source: PloS one [PLoS One] 2013; Vol. 8 (3), pp. e59245. Date of Electronic Publication: 2013 Mar 12.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.

  • Authors : Meng J; Department of Thoracic and Cardiovascular Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America. ; Fang B

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Down-Regulation*/Down-Regulation*/Down-Regulation*/drug effects; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism

  • Source: PloS one [PLoS One] 2010 Sep 27; Vol. 5 (9), pp. e13026. Date of Electronic Publication: 2010 Sep 27.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

MEK1 inhibits cardiac PPARα activity by direct interaction and prevents its nuclear localization.

  • Authors : el Azzouzi H; Interuniversity Cardiology Institute Netherlands, Royal Netherlands Academy of Sciences, Utrecht, The Netherlands.; Leptidis S

Subjects: Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*metabolism ; Myocardium/Myocardium/Myocardium/*metabolism

  • Source: PloS one [PLoS One] 2012; Vol. 7 (6), pp. e36799. Date of Electronic Publication: 2012 Jun 19.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  81 results for ""MAP Kinase Kinase 1""