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Academic Journal

Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms.

  • Authors : Eid S; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.

Subjects: Brain*/Brain*/Brain*/metabolism ; Brain*/Brain*/Brain*/drug effects ; Cardiac Glycosides*/Cardiac Glycosides*/Cardiac Glycosides*/pharmacology

  • Source: PloS one [PLoS One] 2024 Sep 24; Vol. 19 (9), pp. e0308821. Date of Electronic Publication: 2024 Sep 24 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.

  • Authors : Liss M; Neuromuscular and Cardiovascular Cell Biology, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Radke MH

Subjects: Drug Discovery* ; Genes, Reporter*; Cardenolides/Cardenolides/Cardenolides/*pharmacology

  • Source: PloS one [PLoS One] 2018 Jun 11; Vol. 13 (6), pp. e0198492. Date of Electronic Publication: 2018 Jun 11 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Host plant specificity of the monarch butterfly Danaus plexippus: A systematic review and meta-analysis.

  • Authors : Greenstein L; Illinois Natural History Survey, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America.; Ecology and Evolutionary Biology, Tulane University, New Orleans, Louisiana, United States of America.

Subjects: Asclepias* ; Butterflies*; Animals

  • Source: PloS one [PLoS One] 2022 Jun 14; Vol. 17 (6), pp. e0269701. Date of Electronic Publication: 2022 Jun 14 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle.

  • Authors : Leu WJ; School of Pharmacy, National Taiwan University, Taipei, Taiwan.; Chang HS

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cardenolides/Cardenolides/Cardenolides/*pharmacology ; G1 Phase Cell Cycle Checkpoints/G1 Phase Cell Cycle Checkpoints/G1 Phase Cell Cycle Checkpoints/*drug effects

  • Source: PloS one [PLoS One] 2014 Jan 27; Vol. 9 (1), pp. e87323. Date of Electronic Publication: 2014 Jan 27 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions.

  • Authors : Rocha SC; Laboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindú, Divinópolis, MG, Brazil.; Pessoa MT

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Digoxin/Digoxin/Digoxin/*pharmacology ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*drug effects

  • Source: PloS one [PLoS One] 2014 Oct 07; Vol. 9 (10), pp. e108776. Date of Electronic Publication: 2014 Oct 07 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.

  • Authors : Sun Y; Department of Bioengineering and Therapeutic Sciences, Program of Human Genetics, University of California San Francisco, San Francisco, California, United States of America.; Dong Z

Subjects: Cardiac Glycosides/Cardiac Glycosides/Cardiac Glycosides/*pharmacology ; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*drug effects; Animals

  • Source: PloS one [PLoS One] 2012; Vol. 7 (4), pp. e35645. Date of Electronic Publication: 2012 Apr 26.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Toxicarioside A Inhibits Tumor Growth and Angiogenesis: Involvement of TGF-β/Endoglin Signaling.

Subjects: TUMOR growth; CARDENOLIDES; ANTINEOPLASTIC agents

  • Source: PLoS ONE; Nov2012, Vol. 7 Issue 11, Special section p1-13, 13p

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Academic Journal

Ex Vivo Activity of Cardiac Glycosides in Acute Leukaemia.

Subjects: CARDIAC glycosides; LABORATORY animals; PROTEIN synthesis

  • Source: PLoS ONE; 2011, Vol. 6 Issue 1, p1-7, 7p

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  • 1-8 of  8 results for ""Cardenolides""