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Stability of Protein Pharmaceuticals: Recent Advances.

• Authors : Manning MC; Legacy BioDesign LLC, Johnstown, CO, USA. .; Department of Chemistry, Colorado State University, Fort Collins, CO, USA. .

Subjects: Protein Stability* ; Proteins*/Proteins*/Proteins*/chemistry ; Drug Stability*

• Source: Pharmaceutical research [Pharm Res] 2024 Jul; Vol. 41 (7), pp. 1301-1367. Date of Electronic Publication: 2024 Jun 27.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products.

• Authors : Gupta S; Department of Chemical Engineering, DBT Centre of Excellence for Biopharmaceutical Technology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.; Dubey A

Subjects: Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/chemistry ; Protein Stability*; Hydrogen-Ion Concentration

• Source: Pharmaceutical research [Pharm Res] 2024 Jul; Vol. 41 (7), pp. 1443-1454. Date of Electronic Publication: 2024 Jun 28.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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Evaluation of Predictors of Protein Relative Stability Obtained by Solid-State Hydrogen/Deuterium Exchange Monitored by FTIR.

• Authors : Fang R; University of Connecticut, Storrs, Connecticut, USA.; Sterile and Specialty Products, Merck & Co., Inc, NJ, Kenilworth, USA.

Subjects: Protein Stability*; Recombinant Proteins/Recombinant Proteins/Recombinant Proteins/*chemistry ; Serum Albumin, Human/Serum Albumin, Human/Serum Albumin, Human/*chemistry

• Source: Pharmaceutical research [Pharm Res] 2020 Aug 13; Vol. 37 (9), pp. 168. Date of Electronic Publication: 2020 Aug 13.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet

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Assessment of physical stability of an antibody drug conjugate by higher order structure analysis: impact of thiol- maleimide chemistry.

• Authors : Guo J; Biotherapeutics Pharmaceutical Sciences, Pharmaceutical R&D, Pfizer Inc., 700 Chesterfield Parkway West, Chesterfield, MO, 63017, USA.; Kumar S

Subjects: Protein Stability*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*chemistry ; Immunoconjugates/Immunoconjugates/Immunoconjugates/*chemistry

• Source: Pharmaceutical research [Pharm Res] 2014 Jul; Vol. 31 (7), pp. 1710-23. Date of Electronic Publication: 2014 Jan 24.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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Effect of pH and excipients on structure, dynamics, and long-term stability of a model IgG1 monoclonal antibody upon freeze-drying.

• Authors : Park J; Amgen Inc., Process and Product Development, Thousand Oaks, California, 91320, USA.; Nagapudi K

Subjects: Protein Stability*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*chemistry ; Excipients/Excipients/Excipients/*chemistry

• Source: Pharmaceutical research [Pharm Res] 2013 Apr; Vol. 30 (4), pp. 968-84. Date of Electronic Publication: 2012 Nov 27.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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High-throughput screening of excipients intended to prevent antigen aggregation at air-liquid interface.

• Authors : Dasnoy S; Louvain Drug Research Institute, Université catholique de Louvain, Unité de Pharmacie Galénique, Avenue E. Mounier 73, UCL 7320, 1200, Brussels, Belgium.; Dezutter N

Subjects: Air* ; High-Throughput Screening Assays* ; Protein Stability*

• Source: Pharmaceutical research [Pharm Res] 2011 Jul; Vol. 28 (7), pp. 1591-605. Date of Electronic Publication: 2011 Mar 12.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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Application of Affinity-Capture Self-Interaction Nanoparticle Spectroscopy in Predicting Protein Stability, Especially for Co-Formulated Antibodies.

• Authors : Zhou, Meng; Yan, Zhen; Li, Hao

Subjects: PROTEIN stability; IMMUNOGLOBULINS; GEL permeation chromatography

• Source: Pharmaceutical Research; Apr2021, Vol. 38 Issue 4, p721-732, 12p

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Protein Stability and Photostability under In Vitro Vitreal Conditions – Implications for Long Acting Delivery of Protein Therapeutics for Ocular Disease.

• Authors : Mantha, Neelima; Burra, Shalini; Rajagopal, Karthikan

Subjects: OPHTHALMOLOGICAL therapeutics; PROTEIN stability; ADVANCED glycation end-products

• Source: Pharmaceutical Research; May2020, Vol. 37 Issue 5, p1-11, 11p, 1 Diagram, 8 Charts, 3 Graphs

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Agricola

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Molecular Dynamics Modeling Based Investigation of the Effect of Freezing Rate on Lysozyme Stability.

• Authors : Duran, Tibo; Minatovicz, Bruna; Bellucci, Ryan

Subjects: LYSOZYMES; MOLECULAR dynamics; DENATURATION of proteins

• Source: Pharmaceutical Research; Oct2022, Vol. 39 Issue 10, p2585-2596, 12p

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