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Academic Journal

The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets.

  • Authors : Cenciarelli C; Institute of Translational Pharmacology (IFT), National Research Council (CNR), Roma, Italy.; Marei HE

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*drug therapy ; Glioblastoma/Glioblastoma/Glioblastoma/*drug therapy ; Receptor, Notch1/Receptor, Notch1/Receptor, Notch1/*metabolism

  • Source: Oncotarget [Oncotarget] 2017 Mar 14; Vol. 8 (11), pp. 17873-17886.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway.

  • Authors : Wang SC; Cancer Research Institute, Southern Medical University, Guangzhou 510515, China.; Department of Pathology, Guangdong Medical University, Dongguan 523808, China.

Subjects: Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/*metabolism ; Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/*pathology ; PTEN Phosphohydrolase/PTEN Phosphohydrolase/PTEN Phosphohydrolase/*metabolism

  • Source: Oncotarget [Oncotarget] 2015 Nov 03; Vol. 6 (34), pp. 36713-30.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress.

  • Authors : Xu L; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin 300384, China.; Tianjin Research Center of Basic Medical Sciences and Department of Cell Biology, Tianjin Medical University, Tianjin 300070, China.

Subjects: Cell Movement*/Cell Movement*/Cell Movement*/physiology ; Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/physiology; Extracellular Matrix/Extracellular Matrix/Extracellular Matrix/*pathology

  • Source: Oncotarget [Oncotarget] 2017 Mar 28; Vol. 8 (13), pp. 21818-21833.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A three-molecule score based on Notch pathway predicts poor prognosis in non-metastasis clear cell renal cell carcinoma.

  • Authors : Liu Z; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Fu Q

Subjects: Carcinoma, Renal Cell/Carcinoma, Renal Cell/Carcinoma, Renal Cell/*metabolism ; Jagged-1 Protein/Jagged-1 Protein/Jagged-1 Protein/*metabolism ; Kidney Neoplasms/Kidney Neoplasms/Kidney Neoplasms/*metabolism

  • Source: Oncotarget [Oncotarget] 2016 Oct 18; Vol. 7 (42), pp. 68559-68570.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro.

  • Authors : Li Y; School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, 510515, PR. China.; Ye J

Subjects: Acetogenins/Acetogenins/Acetogenins/*pharmacology ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*drug effects ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects

  • Source: Oncotarget [Oncotarget] 2017 Mar 28; Vol. 8 (13), pp. 21140-21152.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Common profiles of Notch signaling differentiate disease-free survival in luminal type A and triple negative breast cancer.

  • Authors : Orzechowska M; Department of Molecular Carcinogenesis, Medical University of Lodz, Lodz, 90-752, Poland.; Jędroszka D

Subjects: Gene Regulatory Networks*; Gene Expression Profiling/Gene Expression Profiling/Gene Expression Profiling/*methods ; Receptors, Notch/Receptors, Notch/Receptors, Notch/*genetics

  • Source: Oncotarget [Oncotarget] 2017 Jan 24; Vol. 8 (4), pp. 6013-6032.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis.

  • Authors : Liu L; Department of Developmental Neuropsychology, School of Psychology, Third Military Medical University, Chongqing, China.; Department of Neurology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.

Subjects: Dentate Gyrus/Dentate Gyrus/Dentate Gyrus/*physiology ; Depression/Depression/Depression/*physiopathology ; Hippocampus/Hippocampus/Hippocampus/*physiology

  • Source: Oncotarget [Oncotarget] 2016 Aug 30; Vol. 7 (35), pp. 56045-56059.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

N-acetylcysteine negatively regulates Notch3 and its malignant signaling.

  • Authors : Zhang X; Department of Preventive Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.; Department of Geriatrics and Neurology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.

Subjects: Acetylcysteine/Acetylcysteine/Acetylcysteine/*pharmacology ; Lysosomes/Lysosomes/Lysosomes/*metabolism ; Reactive Oxygen Species/Reactive Oxygen Species/Reactive Oxygen Species/*metabolism

  • Source: Oncotarget [Oncotarget] 2016 May 24; Vol. 7 (21), pp. 30855-66.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Atracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cells.

  • Authors : Spina R; Department of Neurological Surgery, Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center, Cleveland, OH, USA.; Voss DM

Subjects: Astrocytes/Astrocytes/Astrocytes/*drug effects ; Atracurium/Atracurium/Atracurium/*pharmacology ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*drug therapy

  • Source: Oncotarget [Oncotarget] 2016 Jan 05; Vol. 7 (1), pp. 459-72.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer.

  • Authors : Gao F; Department of Gastroenterology, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.; Huang W

Subjects: Basic Helix-Loop-Helix Transcription Factors/Basic Helix-Loop-Helix Transcription Factors/Basic Helix-Loop-Helix Transcription Factors/*metabolism ; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*metabolism ; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*pathology

  • Source: Oncotarget [Oncotarget] 2015 Nov 17; Vol. 6 (36), pp. 38667-80.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  13 results for ""Transcription Factor HES-1""