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Academic Journal

T-box transcription factor 19 promotes hepatocellular carcinoma metastasis through upregulating EGFR and RAC1.

  • Authors : Ji X; Department of Gastroenterology, Institute of Liver and Gastrointestinal Diseases, Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; Chen X

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism

  • Source: Oncogene [Oncogene] 2022 Apr; Vol. 41 (15), pp. 2225-2238. Date of Electronic Publication: 2022 Feb 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to Rac1 to activate the MAPK pathway.

  • Authors : Huang S; The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.

Subjects: Disease Progression* ; MAP Kinase Signaling System* ; Melanoma*/Melanoma*/Melanoma*/pathology

  • Source: Oncogene [Oncogene] 2021 Sep; Vol. 40 (37), pp. 5626-5638. Date of Electronic Publication: 2021 Jul 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor.

  • Authors : Lorenzo-Martín LF; Centro de Investigación del Cáncer, CSIC-University of Salamanca, 37007, Salamanca, Spain.; Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, 37007, Salamanca, Spain.

Subjects: Proto-Oncogene Proteins c-vav/Proto-Oncogene Proteins c-vav/Proto-Oncogene Proteins c-vav/*genetics ; Rho Guanine Nucleotide Exchange Factors/Rho Guanine Nucleotide Exchange Factors/Rho Guanine Nucleotide Exchange Factors/*genetics ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*genetics

  • Source: Oncogene [Oncogene] 2020 Jul; Vol. 39 (28), pp. 5098-5111. Date of Electronic Publication: 2020 Jun 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells.

  • Authors : Kim I; Department of Biomedical Sciences, Seoul National University College of Medicine, 103 Daehak-ro, Seoul, Republic of Korea.; Cancer Research Institute and Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, 103 Daehak-ro, Seoul, Republic of Korea.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Mixed Function Oxygenases/Mixed Function Oxygenases/Mixed Function Oxygenases/*metabolism ; Repressor Proteins/Repressor Proteins/Repressor Proteins/*metabolism

  • Source: Oncogene [Oncogene] 2019 May; Vol. 38 (19), pp. 3651-3666. Date of Electronic Publication: 2019 Jan 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors.

Subjects: Embryo, Nonmammalian/Embryo, Nonmammalian/Embryo, Nonmammalian/*cytology ; MAP Kinase Kinase 1/MAP Kinase Kinase 1/MAP Kinase Kinase 1/*antagonists & inhibitors ; Melanoma/Melanoma/Melanoma/*drug therapy

  • Source: Oncogene [Oncogene] 2018 Feb 15; Vol. 37 (7), pp. 944-952. Date of Electronic Publication: 2017 Oct 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.

  • Authors : Jin X; Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.; Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China.

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*etiology ; Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/*metabolism ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism

  • Source: Oncogene [Oncogene] 2022 Jan; Vol. 41 (4), pp. 538-549. Date of Electronic Publication: 2021 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intracellular mature IL-37 suppresses tumor metastasis via inhibiting Rac1 activation.

  • Authors : Li Y; Department of Immunology and Key Laboratory of Infection and Immunity of Shandong Province, Shandong University School of Basic Medical Sciences, Jinan, China.; Zhao M

Subjects: Cell Movement* ; Cell Proliferation* ; Gene Expression Regulation, Neoplastic*

  • Source: Oncogene [Oncogene] 2018 Feb 22; Vol. 37 (8), pp. 1095-1106. Date of Electronic Publication: 2017 Nov 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RCC2 is a novel p53 target in suppressing metastasis.

  • Authors : Song C; Institute of Systems Biomedicine, Departments of Pathology and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.; Liang L

Subjects: Gene Expression Regulation, Neoplastic*; Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/*genetics ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics

  • Source: Oncogene [Oncogene] 2018 Jan 04; Vol. 37 (1), pp. 8-17. Date of Electronic Publication: 2017 Sep 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells.

  • Authors : Sun J; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.

Subjects: Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*metabolism ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism; Female

  • Source: Oncogene [Oncogene] 2021 Oct; Vol. 40 (40), pp. 5950-5962. Date of Electronic Publication: 2021 Aug 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.

  • Authors : Turgu B; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, Canada.; Interdisciplinary Oncology Graduate Program, Faculty of Medicine, University of British Columbia, Vancouver, Canada.

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/*genetics ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*genetics ; Tumor Suppressor Proteins/Tumor Suppressor Proteins/Tumor Suppressor Proteins/*genetics

  • Source: Oncogene [Oncogene] 2021 Mar; Vol. 40 (11), pp. 1988-2001. Date of Electronic Publication: 2021 Feb 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  108 results for ""rac1 GTP-Binding Protein""