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Academic Journal

BRD4-specific PROTAC inhibits basal-like breast cancer partially through downregulating KLF5 expression.

  • Authors : Kong Y; Pathology Department, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.; Lan T

Subjects: Kruppel-Like Transcription Factors*/Kruppel-Like Transcription Factors*/Kruppel-Like Transcription Factors*/metabolism ; Kruppel-Like Transcription Factors*/Kruppel-Like Transcription Factors*/Kruppel-Like Transcription Factors*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy

  • Source: Oncogene [Oncogene] 2024 Sep; Vol. 43 (39), pp. 2914-2926. Date of Electronic Publication: 2024 Aug 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer.

  • Authors : Guo S; School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong, China.; Miao M

Subjects: Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/pathology ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/metabolism

  • Source: Oncogene [Oncogene] 2024 May; Vol. 43 (19), pp. 1399-1410. Date of Electronic Publication: 2024 Mar 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis.

  • Authors : Zhang EB; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; Zhang X

Subjects: Terbinafine*/Terbinafine*/Terbinafine*/pharmacology ; Terbinafine*/Terbinafine*/Terbinafine*/therapeutic use ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy

  • Source: Oncogene [Oncogene] 2021 Aug; Vol. 40 (34), pp. 5302-5313. Date of Electronic Publication: 2021 Jul 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Deubiquitinase OTUB2 exacerbates the progression of colorectal cancer by promoting PKM2 activity and glycolysis.

  • Authors : Yu S; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.; Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, China.

Subjects: Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; Deubiquitinating Enzymes/Deubiquitinating Enzymes/Deubiquitinating Enzymes/*metabolism ; Glycolysis/Glycolysis/Glycolysis/*genetics

  • Source: Oncogene [Oncogene] 2022 Jan; Vol. 41 (1), pp. 46-56. Date of Electronic Publication: 2021 Oct 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

S100A7: from mechanism to cancer therapy.

  • Authors : Padilla L; Biomed Division, LEITAT Technological Center, Barcelona, Spain.; Dakhel S

Subjects: Xenograft Model Antitumor Assays*; Neoplasms/Neoplasms/Neoplasms/*metabolism ; Neovascularization, Pathologic/Neovascularization, Pathologic/Neovascularization, Pathologic/*metabolism

  • Source: Oncogene [Oncogene] 2017 Dec 07; Vol. 36 (49), pp. 6749-6761. Date of Electronic Publication: 2017 Aug 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Co-active receptor tyrosine kinases mitigate the effect of FGFR inhibitors in FGFR1-amplified lung cancers with low FGFR1 protein expression.

  • Authors : Kotani H; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Ebi H

Subjects: Xenograft Model Antitumor Assays*; Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*drug therapy ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: Oncogene [Oncogene] 2016 Jul 07; Vol. 35 (27), pp. 3587-97. Date of Electronic Publication: 2015 Nov 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Preclinical modeling of EGFR-specific antibody resistance: oncogenic and immune-associated escape mechanisms.

  • Authors : Garrido G; Tumor Immunology Direction, Molecular Immunology Institute, Center of Molecular Immunology, Havana, Cuba.; Rabasa A

Subjects: Xenograft Model Antitumor Assays*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*pharmacology ; Carcinoma, Lewis Lung/Carcinoma, Lewis Lung/Carcinoma, Lewis Lung/*immunology

  • Source: Oncogene [Oncogene] 2014 Jun 12; Vol. 33 (24), pp. 3129-39. Date of Electronic Publication: 2013 Aug 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model.

  • Authors : Boreddy SR; Department of Biomedical Sciences and Cancer Biology Center, Texas Tech University Health Sciences Center, Amarillo 79106, TX, USA.; Srivastava SK

Subjects: Xenograft Model Antitumor Assays*; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects ; Pancreatic Neoplasms/Pancreatic Neoplasms/Pancreatic Neoplasms/*drug therapy

  • Source: Oncogene [Oncogene] 2013 Aug 22; Vol. 32 (34), pp. 3980-91. Date of Electronic Publication: 2012 Sep 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

MiR-135a functions as a selective killer of malignant glioma.

  • Authors : Wu S; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, PR China.; Lin Y

Subjects: Xenograft Model Antitumor Assays*; Apoptosis/Apoptosis/Apoptosis/*genetics ; Glioma/Glioma/Glioma/*genetics

  • Source: Oncogene [Oncogene] 2012 Aug 23; Vol. 31 (34), pp. 3866-74. Date of Electronic Publication: 2011 Dec 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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Academic Journal

Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.

  • Authors : Sreekanth CN; Integrated Cancer Research Program, Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Bava SV

Subjects: Xenograft Model Antitumor Assays*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Curcumin/Curcumin/Curcumin/*administration & dosage

  • Source: Oncogene [Oncogene] 2011 Jul 14; Vol. 30 (28), pp. 3139-52. Date of Electronic Publication: 2011 Feb 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited

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  • 1-10 of  796 results for ""Xenograft Model Antitumor Assays""