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Academic Journal

CRL2 KLHDC3 and CRL1 Fbxw7 cooperatively mediate c-Myc degradation.

  • Authors : Motomura S; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, 812-8582, Japan.; Yumimoto K

Subjects: F-Box-WD Repeat-Containing Protein 7*/F-Box-WD Repeat-Containing Protein 7*/F-Box-WD Repeat-Containing Protein 7*/metabolism ; F-Box-WD Repeat-Containing Protein 7*/F-Box-WD Repeat-Containing Protein 7*/F-Box-WD Repeat-Containing Protein 7*/genetics ; Proto-Oncogene Proteins c-myc*/Proto-Oncogene Proteins c-myc*/Proto-Oncogene Proteins c-myc*/metabolism

  • Source: Oncogene [Oncogene] 2024 Jun; Vol. 43 (25), pp. 1917-1929. Date of Electronic Publication: 2024 May 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis.

  • Authors : Xie W; Department of Pediatric Neurosurgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Wang J

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics

  • Source: Oncogene [Oncogene] 2024 May; Vol. 43 (19), pp. 1463-1475. Date of Electronic Publication: 2024 Mar 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation.

  • Authors : Buchwald M; Institute of Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University, Jena, Germany.; Pietschmann K

Subjects: Proteolysis*; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism ; Proteasome Endopeptidase Complex/Proteasome Endopeptidase Complex/Proteasome Endopeptidase Complex/*metabolism

  • Source: Oncogene [Oncogene] 2013 Oct 10; Vol. 32 (41), pp. 4913-20. Date of Electronic Publication: 2012 Dec 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor.

Subjects: Gene Expression Profiling* ; Gene Expression Regulation, Neoplastic*; Neoplasms/Neoplasms/Neoplasms/*metabolism

  • Source: Oncogene [Oncogene] 2009 Aug 20; Vol. 28 (33), pp. 2959-68. Date of Electronic Publication: 2009 Jun 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining.

Subjects: *RAD51 recombinase; *UBIQUITIN ligases; *POLYMERIZATION

  • Source: Oncogene. 8/13/2015, Vol. 34 Issue 33, p4403-4411. 9p. 1 Chart, 4 Graphs.

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Academic Journal

Epigenetic modification and a role for the E3 ligase RNF40 in cancer development and metastasis.

  • Authors : Fu J; Key Laboratory of Epigenetics and Oncology, The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou, 646000, Sichuan, China. .; Liao L

Subjects: Epigenesis, Genetic* ; Gene Expression Regulation, Enzymologic* ; Gene Expression Regulation, Neoplastic*

  • Source: Oncogene [Oncogene] 2021 Jan; Vol. 40 (3), pp. 465-474. Date of Electronic Publication: 2020 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases.

Subjects: *UBIQUITIN ligases; *EPIDERMAL growth factor receptors; *PROTEIN-tyrosine kinases

  • Source: Oncogene. 2/20/2014, Vol. 33 Issue 8, p986-995. 10p. 1 Black and White Photograph, 6 Graphs.

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Academic Journal

PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability.

Subjects: *PEROXISOME proliferator-activated receptors; *UBIQUITIN ligases; *MUCINS

  • Source: Oncogene. 12/4/2014, Vol. 33 Issue 49, p5619-5625. 7p. 1 Diagram, 5 Graphs.

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Academic Journal

FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.

Subjects: *UBIQUITIN ligases; *P53 antioncogene; *DNA damage

  • Source: Oncogene. 11/20/2014, Vol. 33 Issue 47, p5424-5433. 10p.

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Academic Journal

Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.

Subjects: *UBIQUITIN ligases; *NEOVASCULARIZATION; *ENDOTHELIAL cells

  • Source: Oncogene. 10/30/2014, Vol. 33 Issue 44, p5211-5220. 10p. 1 Color Photograph, 1 Chart, 7 Graphs.

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  • 1-10 of  941 results for ""UBIQUITIN ligases""