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Editorial & Opinion

Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease?

  • Authors : Wagner M; Institut für Pharmakologie und Toxikologie, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.; Mehel H

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*metabolism ; Heart/Heart/Heart/*innervation ; Heart Failure/Heart Failure/Heart Failure/*enzymology

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2016 Nov; Vol. 389 (11), pp. 1139-1141. Date of Electronic Publication: 2016 Aug 24.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibitors of phosphodiesterases PDE2, PDE3, and PDE4 do not increase the sinoatrial tachycardia of noradrenaline and prostaglandin PGE₁ in mice.

  • Authors : Galindo-Tovar A; Departamento de Tecnología de la Alimentación y Nutrición, Facultad Ciencia de la Salud, Universidad Católica de Murcia, Murcia, 30107, Spain.; Vargas ML

Subjects: Alprostadil* ; Norepinephrine*; Arrhythmia, Sinus/Arrhythmia, Sinus/Arrhythmia, Sinus/*chemically induced

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2016 Feb; Vol. 389 (2), pp. 177-86. Date of Electronic Publication: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium.

  • Authors : Moltzau LR; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Sognsvannsveien 20, P.O. Box 1057 Blindern, N-0316, Oslo, Norway.; Meier S

Subjects: Cyclic GMP/Cyclic GMP/Cyclic GMP/*biosynthesis ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*physiology ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*physiology

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2014 May; Vol. 387 (5), pp. 407-17. Date of Electronic Publication: 2014 Jan 15.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphodiesterase PDE2 activity, increased by isoprenaline, does not reduce β-adrenoceptor-mediated chronotropic and inotropic effects in rat heart.

  • Authors : Galindo-Tovar A; Grado en Farmacia, Facultad Ciencias de la Salud, Universidad Católica San Antonio de Murcia, 30107, Murcia, Spain.; Vargas ML

Subjects: Adrenergic beta-Agonists/Adrenergic beta-Agonists/Adrenergic beta-Agonists/*pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*physiology ; Heart/Heart/Heart/*drug effects

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2018 Jun; Vol. 391 (6), pp. 571-585. Date of Electronic Publication: 2018 Mar 19.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H 2 -histamine-receptor activation in isolated atria of transgenic mice.

  • Authors : Neumann J; Institut für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, Magdeburger Str. 4, D-06112, Halle, Germany.; Voss R

Subjects: Heart Atria/Heart Atria/Heart Atria/*metabolism ; Histamine/Histamine/Histamine/*metabolism ; Receptors, Histamine H2/Receptors, Histamine H2/Receptors, Histamine H2/*metabolism

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2021 Jun; Vol. 394 (6), pp. 1215-1229. Date of Electronic Publication: 2021 Feb 12.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-5 of  5 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""