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Academic Journal

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity.

  • Authors : Bi P; Department of Animal Sciences, Purdue University, West Lafayette, Indiana, USA.; Shan T

Subjects: Adipose Tissue, Brown/Adipose Tissue, Brown/Adipose Tissue, Brown/*drug effects ; Adipose Tissue, White/Adipose Tissue, White/Adipose Tissue, White/*drug effects ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/Immunoglobulin J Recombination Signal Sequence-Binding Protein/Immunoglobulin J Recombination Signal Sequence-Binding Protein/*antagonists & inhibitors

  • Source: Nature medicine [Nat Med] 2014 Aug; Vol. 20 (8), pp. 911-8. Date of Electronic Publication: 2014 Jul 20.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.

  • Authors : Giambra V; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.; Jenkins CR

Subjects: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/pathology ; Protein Kinase C*/Protein Kinase C*/Protein Kinase C*/antagonists & inhibitors

  • Source: Nature medicine [Nat Med] 2012 Nov; Vol. 18 (11), pp. 1693-8. Date of Electronic Publication: 2012 Oct 21.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.

  • Authors : Pajvani UB; Department of Medicine, Columbia University, New York, New York, USA.; Shawber CJ

Subjects: Forkhead Transcription Factors/Forkhead Transcription Factors/Forkhead Transcription Factors/*metabolism ; Glucose/Glucose/Glucose/*metabolism ; Insulin Resistance/Insulin Resistance/Insulin Resistance/*physiology

  • Source: Nature medicine [Nat Med] 2011 Jul 31; Vol. 17 (8), pp. 961-7. Date of Electronic Publication: 2011 Jul 31.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.

  • Authors : Palomero T; Institute for Cancer Genetics, Columbia University, New York, New York 10032, USA.; Sulis ML

Subjects: Drosophila Proteins/Drosophila Proteins/Drosophila Proteins/*genetics ; Gene Expression Regulation, Leukemic/Gene Expression Regulation, Leukemic/Gene Expression Regulation, Leukemic/*genetics ; Leukemia, T-Cell/Leukemia, T-Cell/Leukemia, T-Cell/*metabolism

  • Source: Nature medicine [Nat Med] 2007 Oct; Vol. 13 (10), pp. 1203-10. Date of Electronic Publication: 2007 Sep 16.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

  • Authors : Vilimas T; Department of Medicine, Section of Rheumatology, University of Chicago, 5841 South Maryland Avenue Chicago, Illinois 60637, USA.; Mascarenhas J

Subjects: Leukemia, T-Cell/Leukemia, T-Cell/Leukemia, T-Cell/*pathology ; NF-kappa B/NF-kappa B/NF-kappa B/*metabolism ; Receptor, Notch1/Receptor, Notch1/Receptor, Notch1/*metabolism

  • Source: Nature medicine [Nat Med] 2007 Jan; Vol. 13 (1), pp. 70-7. Date of Electronic Publication: 2006 Dec 17.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.

  • Authors : Arumugam TV; Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, 5600 Nathan Shock Drive, Baltimore, Maryland 21224, USA.; Chan SL

Subjects: Brain/Brain/Brain/*pathology ; Brain Ischemia/Brain Ischemia/Brain Ischemia/*pathology ; Endopeptidases/Endopeptidases/Endopeptidases/*metabolism

  • Source: Nature medicine [Nat Med] 2006 Jun; Vol. 12 (6), pp. 621-3. Date of Electronic Publication: 2006 May 07.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy

  • Source: Nature medicine [Nat Med] 2015 Oct; Vol. 21 (10), pp. 1182-9. Date of Electronic Publication: 2015 Sep 21.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.

Subjects: Enhancer Elements, Genetic* ; Genes, myc*; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics

  • Source: Nature medicine [Nat Med] 2014 Oct; Vol. 20 (10), pp. 1130-7. Date of Electronic Publication: 2014 Sep 07.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Thymocyte transformation enhanced.

  • Authors : Pouliot GP; Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Gutierrez A

Subjects: Enhancer Elements, Genetic* ; Genes, myc*; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics

  • Source: Nature medicine [Nat Med] 2014 Oct; Vol. 20 (10), pp. 1096-7.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Lightening up a notch: Notch regulation of energy metabolism.

  • Authors : Gridley T; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, USA.; Kajimura S

Subjects: Adipose Tissue, Brown/Adipose Tissue, Brown/Adipose Tissue, Brown/*drug effects ; Adipose Tissue, White/Adipose Tissue, White/Adipose Tissue, White/*drug effects ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/Immunoglobulin J Recombination Signal Sequence-Binding Protein/Immunoglobulin J Recombination Signal Sequence-Binding Protein/*antagonists & inhibitors

  • Source: Nature medicine [Nat Med] 2014 Aug; Vol. 20 (8), pp. 811-2.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  26 results for ""Receptor, Notch1""