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Academic Journal

SIRT6 deficiency results in developmental retardation in cynomolgus monkeys.

  • Authors : Zhang W; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Subjects: Developmental Disabilities/Developmental Disabilities/Developmental Disabilities/*genetics ; Macaca fascicularis/Macaca fascicularis/Macaca fascicularis/*genetics ; Sirtuins/Sirtuins/Sirtuins/*deficiency

  • Source: Nature [Nature] 2018 Aug; Vol. 560 (7720), pp. 661-665. Date of Electronic Publication: 2018 Aug 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

Recent progress in the biology and physiology of sirtuins.

  • Authors : Finkel T; Translational Medicine Branch, National Heart Lung and Blood Institute, US National Institutes of Health, Bethesda, Maryland 20892, USA.; Deng CX

Subjects: Sirtuins/Sirtuins/Sirtuins/*physiology; Aging/Aging/Aging/physiology ; Animals

  • Source: Nature [Nature] 2009 Jul 30; Vol. 460 (7255), pp. 587-91.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.

  • Authors : Howitz KT; BIOMOL Research Laboratories, Inc., 5120 Butler Pike, Plymouth Meeting, Pennsylvania 19462, USA.; Bitterman KJ

Subjects: Flavonoids*; Saccharomyces cerevisiae/Saccharomyces cerevisiae/Saccharomyces cerevisiae/*drug effects ; Saccharomyces cerevisiae/Saccharomyces cerevisiae/Saccharomyces cerevisiae/*metabolism

  • Source: Nature [Nature] 2003 Sep 11; Vol. 425 (6954), pp. 191-6. Date of Electronic Publication: 2003 Aug 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Periodical

Ageing: Sorting out the sirtuins.

Subjects: Sex Characteristics*; Longevity/Longevity/Longevity/*physiology ; Sirtuins/Sirtuins/Sirtuins/*metabolism

  • Source: Nature [Nature] 2012 Mar 07; Vol. 483 (7388), pp. 166-7. Date of Electronic Publication: 2012 Mar 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Electronic Cited

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Academic Journal

Sirtuins as potential targets for metabolic syndrome.

  • Authors : Guarente L; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Subjects: Metabolic Syndrome/Metabolic Syndrome/Metabolic Syndrome/*metabolism ; Sirtuins/Sirtuins/Sirtuins/*metabolism; AMP-Activated Protein Kinases

  • Source: Nature [Nature] 2006 Dec 14; Vol. 444 (7121), pp. 868-74.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

The sirtuin SIRT6 regulates lifespan in male mice.

Subjects: SIRTUINS; ANIMAL life spans; TRANSGENIC mice

  • Source: Nature. 3/8/2012, Vol. 483 Issue 7388, p218-221. 4p. 3 Graphs.

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Academic Journal

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.

Subjects: SIRTUINS; SACCHAROMYCES cerevisiae; CAENORHABDITIS elegans

  • Source: Nature. 9/22/2011, Vol. 477 Issue 7365, p482-485. 4p. 2 Graphs.

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Academic Journal

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.

Subjects: Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/Cell Transformation, Neoplastic/*metabolism ; Histone Deacetylases/Histone Deacetylases/Histone Deacetylases/*metabolism ; Histones/Histones/Histones/*metabolism

  • Source: Nature [Nature] 2012 Jul 05; Vol. 487 (7405), pp. 114-8.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

Negative regulation of the deacetylase SIRT1 by DBC1.

  • Authors : Zhao W; Institute for Cancer Genetics, and Department of Pathology College of Physicians and Surgeons, Columbia University, 1130 St Nicholas Avenue, New York, New York 10032, USA.; Kruse JP

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Sirtuins/Sirtuins/Sirtuins/*antagonists & inhibitors ; Sirtuins/Sirtuins/Sirtuins/*metabolism

  • Source: Nature [Nature] 2008 Jan 31; Vol. 451 (7178), pp. 587-90.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

DBC1 is a negative regulator of SIRT1.

  • Authors : Kim JE; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.; Chen J

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Sirtuins/Sirtuins/Sirtuins/*antagonists & inhibitors ; Sirtuins/Sirtuins/Sirtuins/*metabolism

  • Source: Nature [Nature] 2008 Jan 31; Vol. 451 (7178), pp. 583-6.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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  • 1-10 of  637 results for ""Sirtuins""