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Academic Journal

PGE 2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.

  • Authors : Morotti M; Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne (UNIL), Lausanne, Switzerland.; Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/cytology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism

  • Source: Nature [Nature] 2024 May; Vol. 629 (8011), pp. 426-434. Date of Electronic Publication: 2024 Apr 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

PD-1 combination therapy with IL-2 modifies CD8 + T cell exhaustion program.

  • Authors : Hashimoto M; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/cytology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/drug effects ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology

  • Source: Nature [Nature] 2022 Oct; Vol. 610 (7930), pp. 173-181. Date of Electronic Publication: 2022 Sep 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2.

  • Authors : Zhou L; Division of Gastroenterology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.

Subjects: Immunity, Innate/Immunity, Innate/Immunity, Innate/*immunology ; Interleukin-2/Interleukin-2/Interleukin-2/*immunology ; Intestines/Intestines/Intestines/*cytology

  • Source: Nature [Nature] 2019 Apr; Vol. 568 (7752), pp. 405-409. Date of Electronic Publication: 2019 Apr 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

An engineered IL-2 partial agonist promotes CD8 + T cell stemness.

  • Authors : Mo F; Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Yu Z

Subjects: Drug Partial Agonism*; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*cytology ; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*drug effects

  • Source: Nature [Nature] 2021 Sep; Vol. 597 (7877), pp. 544-548. Date of Electronic Publication: 2021 Sep 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

De novo design of potent and selective mimics of IL-2 and IL-15.

  • Authors : Silva DA; Institute for Protein Design, University of Washington, Seattle, WA, USA. .; Department of Biochemistry, University of Washington, Seattle, WA, USA. .

Subjects: Drug Design* ; Molecular Mimicry*; Interleukin-15/Interleukin-15/Interleukin-15/*immunology

  • Source: Nature [Nature] 2019 Jan; Vol. 565 (7738), pp. 186-191. Date of Electronic Publication: 2019 Jan 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Periodical

Designer protein delivers signal of choice.

Subjects: Interleukin-15* ; Interleukin-2*; Computational Biology

  • Source: Nature [Nature] 2019 Jan; Vol. 565 (7738), pp. 165-166.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

  • Authors : Levin AM; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.; Bates DL

Subjects: Directed Molecular Evolution* ; Protein Engineering*; Interleukin-2/Interleukin-2/Interleukin-2/*chemistry

  • Source: Nature [Nature] 2012 Mar 25; Vol. 484 (7395), pp. 529-33. Date of Electronic Publication: 2012 Mar 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Electronic Cited

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Academic Journal

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

  • Authors : Williams MA; Howard Hughes Medical Institute and Department of Immunology, University of Washington, Seattle, Washington 98195, USA.; Tyznik AJ

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*cytology ; CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology

  • Source: Nature [Nature] 2006 Jun 15; Vol. 441 (7095), pp. 890-3.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis.

  • Authors : Lenardo MJ; Laboratory of Immunology, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892.

Subjects: CD4 Antigens/CD4 Antigens/CD4 Antigens/*physiology ; Cell Death/Cell Death/Cell Death/*drug effects ; Interleukin-2/Interleukin-2/Interleukin-2/*pharmacology

  • Source: Nature [Nature] 1991 Oct 31; Vol. 353 (6347), pp. 858-61.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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Academic Journal

EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells.

  • Authors : Li J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California 94143, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, California 94143, USA.

Subjects: Cell Differentiation*; Dendritic Cells/Dendritic Cells/Dendritic Cells/*immunology ; Interleukin-2/Interleukin-2/Interleukin-2/*immunology

  • Source: Nature [Nature] 2016 May 05; Vol. 533 (7601), pp. 110-4.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium:

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  • 1-10 of  1,575 results for ""INTERLEUKIN-2""