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Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

• Authors : Venot Q; INSERM U1151, Institut Necker Enfants Malades, Paris, France.; Blanc T

Subjects: Molecular Targeted Therapy*; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors ; Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/Class I Phosphatidylinositol 3-Kinases/*metabolism Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi

• Source: Nature [Nature] 2018 Jun; Vol. 558 (7711), pp. 540-546. Date of Electronic Publication: 2018 Jun 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Physiology: A road block for blood vessels.

Subjects: VASCULAR endothelial growth factors; BLOOD-vessel abnormalities; CARMELIET, Peter

• Source: Nature. 12/19/2013, Vol. 504 Issue 7480, p335-335. 1p.

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Cancer biology: Room to breathe.

Subjects: TUMOR blood vessels; BLOOD-vessel abnormalities; PHYSIOLOGICAL transport of oxygen

• Source: Nature. 2/19/2009, Vol. 457 Issue 7232, p939-939. 1p.

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