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Publication : nature

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Academic Journal

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

Authors : Pelish, Henry E.; Liau, Brian B.; Nitulescu, Ioana I.

Subjects: KINASE inhibitors; ACUTE myeloid leukemia; TRANSCRIPTION factors

Source: Nature. 10/8/2015, Vol. 526 Issue 7572, p273-276. 4p. 1 Diagram, 2 Charts, 11 Graphs.

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Academic Journal

BET inhibitor resistance emerges from leukaemia stem cells.

Authors : Fong, Chun Yew; Gilan, Omer; Lam, Enid Y. N.

Subjects: BROMODOMAIN-containing proteins; ACUTE myeloid leukemia; LEUKEMIA treatment

Source: Nature. 9/24/2015, Vol. 525 Issue 7570, p538-542. 5p. 1 Diagram, 13 Graphs.

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Academic Journal

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.

Authors : Rathert, Philipp; Roth, Mareike; Neumann, Tobias

Subjects: GENE regulatory networks; ACUTE myeloid leukemia; BROMODOMAIN-containing proteins

Source: Nature. 9/24/2015, Vol. 525 Issue 7570, p543-547. 5p. 14 Graphs.

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Academic Journal

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

Authors : Wong, Terrence N.; Ramsingh, Giridharan; Young, Andrew L.

Subjects: ACUTE myeloid leukemia; MYELODYSPLASTIC syndromes; P53 protein

Source: Nature. 2/25/2015, Vol. 518 Issue 7540, p552-555. 4p. 1 Diagram, 4 Charts, 9 Graphs.

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Academic Journal

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.

Authors : Shlush, Liran I.; Zandi, Sasan; Mitchell, Amanda

Subjects: ACUTE myeloid leukemia; STEM cells; CANCER chemotherapy

Source: Nature. 2/20/2014, Vol. 506 Issue 7488, p328-333. 6p. 1 Black and White Photograph, 2 Diagrams, 7 Graphs.

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Academic Journal

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.

Authors : Smith, Catherine C.; Wang, Qi; Chin, Chen-Shan

Subjects: ACUTE myeloid leukemia; CANCER patients; CANCER prognosis

Source: Nature. 5/10/2012, Vol. 485 Issue 7397, p260-263. 4p.

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Academic Journal

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.

Authors : Ding, Li; Ley, Timothy J.; Larson, David E.

Subjects: ACUTE myeloid leukemia; ANTIBODY diversity; NUCLEOTIDE sequence

Source: Nature. 1/26/2012, Vol. 481 Issue 7382, p506-510. 5p. 1 Color Photograph, 1 Chart, 2 Graphs.

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Academic Journal

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1.

Authors : Ono, Masahiro; Yaguchi, Hiroko; Ohkura, Naganari

Subjects: T cells; ACUTE myeloid leukemia; IMMUNOREGULATION

Source: Nature. 4/5/2007, Vol. 446 Issue 7136, p685-689. 5p. 4 Graphs.

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Academic Journal

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia.

Authors : Casirati G; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Milano-Bicocca University, Milan, Italy.

Subjects: Epitopes*/Epitopes*/Epitopes*/genetics ; Epitopes*/Epitopes*/Epitopes*/immunology ; Gene Editing*

Source: Nature [Nature] 2023 Sep; Vol. 621 (7978), pp. 404-414. Date of Electronic Publication: 2023 Aug 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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Academic Journal

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.

Authors : Issa GC; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .; Aldoss I

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Histone-Lysine N-Methyltransferase*/Histone-Lysine N-Methyltransferase*/Histone-Lysine N-Methyltransferase*/chemistry

Source: Nature [Nature] 2023 Mar; Vol. 615 (7954), pp. 920-924. Date of Electronic Publication: 2023 Mar 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited

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