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Academic Journal

Gene therapy returns to centre stage.

Authors : Naldini, Luigi

Subjects: GENE therapy; CLINICAL trials; GENE delivery techniques

Source: Nature. 10/15/2015, Vol. 526 Issue 7573, p351-360. 10p. 1 Chart.

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Academic Journal

Redox rhythm reinforces the circadian clock to gate immune response.

Authors : Zhou, Mian; Wang, Wei; Karapetyan, Sargis

Subjects: CIRCADIAN rhythms; ARABIDOPSIS; METABOLIC regulation

Source: Nature. 7/23/2015, Vol. 523 Issue 7561, p472-476. 5p. 1 Diagram, 1 Chart, 12 Graphs.

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Academic Journal

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation.

Authors : Gagliani, Nicola; Vesely, Maria Carolina Amezcua; Iseppon, Andrea

Subjects: T cells; CYTOLOGICAL research; INFLAMMATION

Source: Nature. 7/9/2015, Vol. 523 Issue 7559, p221-225. 5p. 13 Graphs.

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Academic Journal

Mitochondrial DNA stress primes the antiviral innate immune response.

Authors : West, A. Phillip; Khoury-Hanold, William; Staron, Matthew

Subjects: MITOCHONDRIAL DNA; PHYSIOLOGICAL stress; IMMUNE response

Source: Nature. 4/23/2015, Vol. 520 Issue 7548, p553-557. 5p. 1 Diagram, 2 Charts, 11 Graphs.

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Academic Journal

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection.

Authors : Pellegrino, Mark W.; Nargund, Amrita M.; Kirienko, Natalia V.

Subjects: METAZOA; TRANSCRIPTION factors; IMMUNE response

Source: Nature. 12/18/2014, Vol. 516 Issue 7531, p414-417. 4p.

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Academic Journal

PD-1 blockade induces responses by inhibiting adaptive immune resistance.

Authors : Tumeh, Paul C.; Chmielowski, Bartosz; Glaspy, John A.

Subjects: CANCER patients; IMMUNE response; ANTIGENS

Source: Nature. 11/27/2014, Vol. 515 Issue 7528, p568-571. 4p.

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Academic Journal

A vaccine targeting mutant IDH1 induces antitumour immunity.

Authors : Schumacher, Theresa; Bunse, Lukas; Pusch, Stefan

Subjects: ANTINEOPLASTIC agents; ISOCITRATE dehydrogenase; IMMUNOTHERAPY

Source: Nature. 8/21/2014, Vol. 512 Issue 7514, p324-327. 4p.

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Academic Journal

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.

Authors : Noubade, Rajkumar; Wong, Kit; Ota, Naruhisa

Subjects: REACTIVE oxygen species; AUTOIMMUNITY; PHAGOCYTES

Source: Nature. 5/8/2014, Vol. 509 Issue 7499, p235-239. 5p. 5 Graphs.

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Academic Journal

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling.

Authors : Nakamura, Norihiro; Lill, Jennie R.; Phung, Qui

Subjects: ENDOSOMES; PATHOGENIC microorganisms; TOLL-like receptors

Source: Nature. 5/8/2014, Vol. 509 Issue 7499, p240-244. 5p. 4 Graphs.

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Academic Journal

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development.

Authors : Liu, Xindong; Chen, Xin; Zhong, Bo

Subjects: T helper cells; DEVELOPMENTAL cytology; TRANSCRIPTION factors

Source: Nature. 3/27/2014, Vol. 507 Issue 7493, p513-518. 6p.

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