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Academic Journal

Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[ e ]imidazo[2,1- c ][1,2,4]triazines as Phosphodiesterase 2A Inhibitors.

  • Authors : Ritawidya R; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceuticals Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany. .; Center for Radioisotope and Radiopharmaceutical Technology, National Nuclear and Energy Agency (BATAN), Puspiptek Area, Serpong, South Tangerang, Indonesia. .

Subjects: Brain/Brain/Brain/*enzymology ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*antagonists & inhibitors ; Radiopharmaceuticals/Radiopharmaceuticals/Radiopharmaceuticals/*chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2019 Jul 31; Vol. 24 (15). Date of Electronic Publication: 2019 Jul 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Investigation of an 18 F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A.

  • Authors : Schröder S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig 04318, Germany. .; Wenzel B

Subjects: Brain/Brain/Brain/*enzymology ; Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*analysis ; Imidazoles/Imidazoles/Imidazoles/*chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2018 Mar 02; Vol. 23 (3). Date of Electronic Publication: 2018 Mar 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Synthesis, 18F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography.

  • Authors : Schröder S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, Leipzig 04318, Germany. .; Wenzel B

Subjects: Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/Cyclic Nucleotide Phosphodiesterases, Type 2/*metabolism ; Isotope Labeling/Isotope Labeling/Isotope Labeling/*methods ; Neuroimaging/Neuroimaging/Neuroimaging/*methods

  • Source: Molecules (Basel, Switzerland) [Molecules] 2015 May 26; Vol. 20 (6), pp. 9591-615. Date of Electronic Publication: 2015 May 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography.

  • Authors : Ritawidya R; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Department of Neuroradiopharmaceuticals, 04318 Leipzig, Germany.; Center for Radioisotope and Radiopharmaceutical Technology, National Nuclear Energy Agency (BATAN), Puspiptek Area, Serpong, South Tangerang 15314, Indonesia.

Subjects: Brain*/Brain*/Brain*/diagnostic imaging ; Brain*/Brain*/Brain*/enzymology ; Fluorine Radioisotopes*/Fluorine Radioisotopes*/Fluorine Radioisotopes*/chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2019 Nov 15; Vol. 24 (22). Date of Electronic Publication: 2019 Nov 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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  • 1-4 of  4 results for ""Cyclic Nucleotide Phosphodiesterases, Type 2""