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  • 1-10 of  10 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""

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Academic Journal

PDE3 and PDE4 isozyme-selective inhibitors are both required for synergistic activation of brown adipose tissue.

  • Authors : Kraynik SM; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Miyaoka RS

Subjects: Adipose Tissue, Brown/Adipose Tissue, Brown/Adipose Tissue, Brown/*drug effects ; Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/Phosphodiesterase 3 Inhibitors/*pharmacology ; Phosphodiesterase 4 Inhibitors/Phosphodiesterase 4 Inhibitors/Phosphodiesterase 4 Inhibitors/*pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2013 Jun; Vol. 83 (6), pp. 1155-65. Date of Electronic Publication: 2013 Mar 14.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model:

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Academic Journal

Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis.

  • Authors : Netherton SJ; Department of Pharmacology and Toxicology, Botterell Hall, Queen's University, Kingston, Ontario K7L 3N6, Canada.; Maurice DH

Subjects: 2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/*genetics ; 2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/*metabolism ; Cell Movement/Cell Movement/Cell Movement/*physiology

  • Source: Molecular pharmacology [Mol Pharmacol] 2005 Jan; Vol. 67 (1), pp. 263-72. Date of Electronic Publication: 2004 Oct 08.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model:

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Academic Journal

Commitment of activated T cells to secondary responsiveness is enhanced by signals mediated by cAMP-dependent protein kinase A-I.

  • Authors : Vig M; National Institute of Immunology, New Delhi, India.; George A

Subjects: Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/*physiology ; Isoenzymes/Isoenzymes/Isoenzymes/*physiology ; Lymphocyte Activation/Lymphocyte Activation/Lymphocyte Activation/*physiology

  • Source: Molecular pharmacology [Mol Pharmacol] 2002 Dec; Vol. 62 (6), pp. 1471-81.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo.

  • Authors : Tilley DG; Department of Pharmacology and Toxicology, Queen's University, Kingston, Ontario, Canada.; Maurice DH

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Bucladesine/Bucladesine/Bucladesine/*pharmacology ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: Molecular pharmacology [Mol Pharmacol] 2002 Sep; Vol. 62 (3), pp. 497-506.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Identification of interaction sites of cyclic nucleotide phosphodiesterase type 3A with milrinone and cilostazol using molecular modeling and site-directed mutagenesis.

  • Authors : Zhang W; The Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.; Ke H

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Milrinone/Milrinone/Milrinone/*pharmacology ; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2002 Sep; Vol. 62 (3), pp. 514-20.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Reduced phosphodiesterase 3 activity and phosphodiesterase 3A level in synthetic vascular smooth muscle cells: implications for use of phosphodiesterase 3 inhibitors in cardiovascular tissues.

  • Authors : Dunkerley HA; Department of Pharmacology and Toxicology, Queen's University at Kingston, Kingston, Ontario, Canada.; Tilley DG

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Cardiovascular System/Cardiovascular System/Cardiovascular System/*drug effects ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*enzymology

  • Source: Molecular pharmacology [Mol Pharmacol] 2002 May; Vol. 61 (5), pp. 1033-40.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK).

  • Authors : Baillie G; Molecular Pharmacology Group, Division of Biochemistry & Molecular Biology, Institute of Biomedical & Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.; MacKenzie SJ

Subjects: 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*metabolism ; Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/*metabolism ; Mitogen-Activated Protein Kinases/Mitogen-Activated Protein Kinases/Mitogen-Activated Protein Kinases/*metabolism

  • Source: Molecular pharmacology [Mol Pharmacol] 2001 Nov; Vol. 60 (5), pp. 1100-11.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A.

  • Authors : Osinski MT; Institut für Pharmakologie und Klinische Pharmakologie, Heinrich-Heine-Universität Düsseldorf, Germany.; Rauch BH

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/Cyclic AMP-Dependent Protein Kinases/*metabolism ; Nitrates/Nitrates/Nitrates/*pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2001 May; Vol. 59 (5), pp. 1044-50.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Dual expression and differential regulation of phosphodiesterase 3A and phosphodiesterase 3B in human vascular smooth muscle: implications for phosphodiesterase 3 inhibition in human cardiovascular tissues.

  • Authors : Palmer D; Department of Pharmacology & Toxicology, Queen's University, Kingston, Ontario, Canada.; Maurice DH

Subjects: Gene Expression Regulation, Enzymologic*; 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*genetics ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*enzymology

  • Source: Molecular pharmacology [Mol Pharmacol] 2000 Aug; Vol. 58 (2), pp. 247-52.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Academic Journal

Differential inhibition of multiple cAMP phosphodiesterase isozymes by isoflavones and tyrphostins.

  • Authors : Nichols MR; Department of Chemistry, Purdue University, West Lafayette, Indiana, USA.; Morimoto BH

Subjects: Phosphoric Diester Hydrolases*; 3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/3',5'-Cyclic-AMP Phosphodiesterases/*antagonists & inhibitors ; 3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/3',5'-Cyclic-GMP Phosphodiesterases/*antagonists & inhibitors

  • Source: Molecular pharmacology [Mol Pharmacol] 2000 Apr; Vol. 57 (4), pp. 738-45.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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  • 1-10 of  10 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""