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Academic Journal

Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model.

  • Authors : Bechtold BJ; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States.; Lynch KD

Subjects: Rifampin*/Rifampin*/Rifampin*/pharmacokinetics ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/genetics ; Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/metabolism

  • Source: Molecular pharmaceutics [Mol Pharm] 2024 May 06; Vol. 21 (5), pp. 2284-2297. Date of Electronic Publication: 2024 Mar 26.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder.

  • Authors : Häkkinen K; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio FI-70240, Finland.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki FI-00014, Finland.

Subjects: Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/Liver-Specific Organic Anion Transporter 1*/genetics ; Psychotic Disorders*; Humans

  • Source: Molecular pharmaceutics [Mol Pharm] 2023 Mar 06; Vol. 20 (3), pp. 1500-1508. Date of Electronic Publication: 2023 Feb 13.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

In Silico and in Vitro Assessment of OATP1B1 Inhibition in Drug Discovery.

Subjects: Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*pharmacology

  • Source: Molecular pharmaceutics [Mol Pharm] 2018 Aug 06; Vol. 15 (8), pp. 3060-3068. Date of Electronic Publication: 2018 Jul 05.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Relative Activity Factor (RAF)-Based Scaling of Uptake Clearance Mediated by Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 in Human Hepatocytes.

  • Authors : Izumi S; Drug Metabolism and Pharmacokinetics Tsukuba , Tsukuba Research Laboratories, Eisai Co., Ltd. , 5-1-3 Tokodai , Tsukuba-shi , Ibaraki 300-2635 , Japan.; Nozaki Y

Subjects: Hepatocytes/Hepatocytes/Hepatocytes/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism ; Pharmaceutical Preparations/Pharmaceutical Preparations/Pharmaceutical Preparations/*metabolism

  • Source: Molecular pharmaceutics [Mol Pharm] 2018 Jun 04; Vol. 15 (6), pp. 2277-2288. Date of Electronic Publication: 2018 May 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8).

  • Authors : Maeda K; Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.; Kambara M

Subjects: Hepatocytes/Hepatocytes/Hepatocytes/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*physiology ; Organic Anion Transporters, Sodium-Dependent/Organic Anion Transporters, Sodium-Dependent/Organic Anion Transporters, Sodium-Dependent/*physiology

  • Source: Molecular pharmaceutics [Mol Pharm] 2006 Jan-Feb; Vol. 3 (1), pp. 70-7.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Oligomerization Study of Human Organic Anion Transporting Polypeptide 1B1.

  • Authors : Ni C; College of Life Sciences, South China Agricultural University , Guangzhou 541642, China.; Yu X

Subjects: Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism ; Organic Anion Transporters/Organic Anion Transporters/Organic Anion Transporters/*metabolism; Biological Transport/Biological Transport/Biological Transport/physiology

  • Source: Molecular pharmaceutics [Mol Pharm] 2017 Feb 06; Vol. 14 (2), pp. 359-367. Date of Electronic Publication: 2017 Jan 12.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Investigation of Fluorescein Derivatives as Substrates of Organic Anion Transporting Polypeptide (OATP) 1B1 To Develop Sensitive Fluorescence-Based OATP1B1 Inhibition Assays.

  • Authors : Izumi S; Drug Metabolism and Pharmacokinetics Japan, Tsukuba Research Laboratories, Eisai Co. Ltd., 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan.; Nozaki Y

Subjects: Biological Assay/Biological Assay/Biological Assay/*methods ; Fluorescein/Fluorescein/Fluorescein/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*antagonists & inhibitors

  • Source: Molecular pharmaceutics [Mol Pharm] 2016 Feb 01; Vol. 13 (2), pp. 438-48. Date of Electronic Publication: 2016 Jan 07.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions.

  • Authors : Alam K; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center , Oklahoma City, Oklahoma 73117, United States.; Pahwa S

Subjects: Drug Interactions*; Chloroquine/Chloroquine/Chloroquine/*pharmacology ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*drug effects

  • Source: Molecular pharmaceutics [Mol Pharm] 2016 Mar 07; Vol. 13 (3), pp. 839-51. Date of Electronic Publication: 2016 Feb 01.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.

  • Authors : Misaka S; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen, Germany.; Department of Pharmacology, School of Medicine, Fukushima Medical University , Fukushima, Japan.

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism ; Nadolol/Nadolol/Nadolol/*metabolism

  • Source: Molecular pharmaceutics [Mol Pharm] 2016 Feb 01; Vol. 13 (2), pp. 512-9. Date of Electronic Publication: 2016 Jan 19.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice.

  • Authors : Loos NHC; Division of Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.; Ferreira Martins ML

Subjects: Organic Anion Transporters*/Organic Anion Transporters*/Organic Anion Transporters*/metabolism ; Organic Anion Transporters, Sodium-Independent*/Organic Anion Transporters, Sodium-Independent*/Organic Anion Transporters, Sodium-Independent*/metabolism ; Taxoids*

  • Source: Molecular pharmaceutics [Mol Pharm] 2024 Apr 01; Vol. 21 (4), pp. 1952-1964. Date of Electronic Publication: 2024 Feb 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  24 results for ""Liver-Specific Organic Anion Transporter 1""