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Academic Journal

SP1‑mediated ADAMTS5 transcription promotes IL‑1β‑induced chondrocyte injury via Wnt/β‑catenin pathway in osteoarthritis.

  • Authors : Hao X; Department of Teaching Administration, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.; Wu X

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/pathology ; Sp1 Transcription Factor*/Sp1 Transcription Factor*/Sp1 Transcription Factor*/metabolism

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Aug; Vol. 30 (2). Date of Electronic Publication: 2024 Jun 28.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Detection of miR-29a in plasma of patients with lumbar spinal stenosis and the clinical significance.

Subjects: SPINAL stenosis; MICRORNA genetics; REVERSE transcriptase polymerase chain reaction

  • Source: Molecular Medicine Reports; Jul2018, Vol. 18 Issue 1, p223-229, 7p

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Academic Journal

GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.

Subjects: EXTRACELLULAR matrix; INFLAMMATION; PATHOLOGICAL physiology

  • Source: Molecular Medicine Reports; Jul2024, Vol. 30 Issue 1, pN.PAG-N.PAG, 1p

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Academic Journal

Interleukin-1β-mediated suppression of microRNA-27a-3p activity in human cartilage via MAPK and NF-κB pathways: A potential mechanism of osteoarthritis pathogenesis.

Subjects: MICRORNA; OSTEOARTHRITIS treatment; INTERLEUKIN-1

  • Source: Molecular Medicine Reports; Jul2018, Vol. 18 Issue 1, p541-549, 9p

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Academic Journal

Anti‑inflammatory and anti‑catabolic effect of non‑animal stabilized hyaluronic acid and mesenchymal stem cell‑conditioned medium in an osteoarthritis coculture model.

  • Authors : Simental-Mendía M; Orthopedics and Traumatology Service, School of Medicine and University Hospital 'Dr. José Eleuterio González', Universidad Autonoma de Nuevo León, Monterrey, Nuevo León 64460, México.; Lozano-Sepúlveda SA

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Cartilage/Cartilage/Cartilage/*drug effects ; Culture Media, Conditioned/Culture Media, Conditioned/Culture Media, Conditioned/*pharmacology

  • Source: Molecular medicine reports [Mol Med Rep] 2020 May; Vol. 21 (5), pp. 2243-2250. Date of Electronic Publication: 2020 Feb 26.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways.

  • Authors : Huang X; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.; Pan Q

Subjects: Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*pharmacology ; Kaempferols/Kaempferols/Kaempferols/*pharmacology ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*drug effects

  • Source: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 2697-2704. Date of Electronic Publication: 2018 Jul 16.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Leptin modulates the expression of catabolic genes in rat nucleus pulposus cells through the mitogen-activated protein kinase and Janus kinase 2/signal transducer and activator of transcription 3 pathways.

  • Authors : Miao D; Department of Orthopedic Surgery, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, Zhejiang 325200, P.R. China.; Zhang L

Subjects: Janus Kinase 2/Janus Kinase 2/Janus Kinase 2/*metabolism ; Leptin/Leptin/Leptin/*pharmacology; ADAM Proteins/ADAM Proteins/ADAM Proteins/genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2015 Aug; Vol. 12 (2), pp. 1761-8. Date of Electronic Publication: 2015 Apr 20.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Visceral adipose tissue-derived serine protease inhibitor inhibits interleukin-1β-induced catabolic and inflammatory responses in murine chondrocytes.

  • Authors : Bao JP; Department of Orthopedics Surgery, The Second Hospital of Medical College, Zhejiang University, Hangzhou, Zhejiang 310009, P.R. China.; Jiang LF

Subjects: Adipokines/Adipokines/Adipokines/*toxicity ; Chondrocytes/Chondrocytes/Chondrocytes/*drug effects ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*pharmacology

  • Source: Molecular medicine reports [Mol Med Rep] 2014 Oct; Vol. 10 (4), pp. 2191-7. Date of Electronic Publication: 2014 Aug 11.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling.

  • Authors : Feng ZY; Department of Orthopedics, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China.; He ZN

Subjects: ADAM Proteins/ADAM Proteins/ADAM Proteins/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*cytology ; Chondrocytes/Chondrocytes/Chondrocytes/*enzymology

  • Source: Molecular medicine reports [Mol Med Rep] 2013 Dec; Vol. 8 (6), pp. 1669-79. Date of Electronic Publication: 2013 Oct 08.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-9 of  9 results for ""ADAMTS5 Protein""