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Academic Journal

How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini.

  • Authors : Sherpa D; Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Bavaria, Germany.; Chrustowicz J

Subjects: Ubiquitin*/Ubiquitin*/Ubiquitin*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism; Amino Acid Motifs

  • Source: Molecular cell [Mol Cell] 2022 Apr 21; Vol. 82 (8), pp. 1424-1438. Date of Electronic Publication: 2022 Mar 04.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis.

  • Authors : Hundley FV; Department of Biochemistry and Biophysics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA.

Subjects: CRISPR-Cas Systems* ; Mitosis* ; Signal Transduction*

  • Source: Molecular cell [Mol Cell] 2021 Mar 18; Vol. 81 (6), pp. 1319-1336.e9. Date of Electronic Publication: 2021 Feb 03.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.

  • Authors : Kato K; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.

Subjects: Immunity, Innate*; DEAD Box Protein 58/DEAD Box Protein 58/DEAD Box Protein 58/*metabolism ; Interferon-Induced Helicase, IFIH1/Interferon-Induced Helicase, IFIH1/Interferon-Induced Helicase, IFIH1/*metabolism

  • Source: Molecular cell [Mol Cell] 2021 Feb 04; Vol. 81 (3), pp. 599-613.e8. Date of Electronic Publication: 2020 Dec 28.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The picky mTORC1 in metabolic enzyme degradation.

Subjects: *ENZYMES; *UBIQUITIN ligases

  • Source: Molecular Cell. Jun2024, Vol. 84 Issue 11, p2011-2013. 3p.

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Academic Journal

Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping.

Subjects: *UBIQUITIN ligases

  • Source: Molecular Cell. Nov2023, Vol. 83 Issue 22, p4191-4192. 2p.

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Academic Journal

Cryo-EM reveals important regulatory mechanism of the workhorses of targeted protein degradation.

Subjects: *PROTEOLYSIS; *UBIQUITIN ligases; *UBIQUITIN

  • Source: Molecular Cell. Jul2023, Vol. 83 Issue 13, p2159-2160. 2p.

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Academic Journal

A Tunable Brake for HECT Ubiquitin Ligases.

  • Authors : Chen Z; Department of Pharmacology and Molecular Sciences, John Hopkins School of Medicine, Baltimore, MD 21205, USA.; Jiang H

Subjects: Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/Endosomal Sorting Complexes Required for Transport/*metabolism ; Repressor Proteins/Repressor Proteins/Repressor Proteins/*metabolism ; Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/Ubiquitin-Protein Ligases/*metabolism

  • Source: Molecular cell [Mol Cell] 2017 May 04; Vol. 66 (3), pp. 345-357.e6.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164

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Academic Journal

Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.

  • Authors : Hang LE; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Peng J

Subjects: DNA Replication* ; Gene Expression Regulation, Fungal*; Endodeoxyribonucleases/Endodeoxyribonucleases/Endodeoxyribonucleases/*genetics

  • Source: Molecular cell [Mol Cell] 2015 Oct 15; Vol. 60 (2), pp. 268-79. Date of Electronic Publication: 2015 Oct 01.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.

  • Authors : Jiang X; Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.; Charlat O

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Oncogene Proteins/Oncogene Proteins/Oncogene Proteins/*metabolism

  • Source: Molecular cell [Mol Cell] 2015 May 07; Vol. 58 (3), pp. 522-33. Date of Electronic Publication: 2015 Apr 16.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lactate fuels mitosis.

Subjects: *UBIQUITIN ligases; *LACTATES; *LACTATION

  • Source: Molecular Cell. May2023, Vol. 83 Issue 10, p1549-1551. 3p.

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  • 1-10 of  748 results for ""UBIQUITIN ligases""