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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

• Authors : Leckie, Margaret J; ten Brinke, Anneke; Khan, Jamey

Subjects: INTERLEUKIN-5; ASTHMA treatment; THERAPEUTIC use of monoclonal antibodies

• Source: Lancet. 12/23/2000, Vol. 356 Issue 9248, p2144-2148. 5p. 1 Diagram, 2 Graphs.

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Treatment for severe eosinophilic asthma-consistent effect of anti-interleukin-5 antibodies?

• Authors : Castro, Mario¹ ; Bacharier, Leonard B.²

Subjects: *RESEARCH; ASTHMA treatment; INTERLEUKIN-5

• Source: Lancet. 10/29/2016, Vol. 388 Issue 10056, p2059-2060. 2p.

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Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial.

• Authors : FitzGerald, J. Mark; Bleecker, Eugene R.; Nair, Parameswaran

Subjects: INTERLEUKIN-5; CLINICAL trials; MONOCLONAL antibodies

• Source: Lancet. 10/29/2016, Vol. 388 Issue 10056, p2128-2141. 14p.

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An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children.

• Authors : Heaton, T.; Rowe, J.; Aalberse, R. C.

Subjects: ASTHMA in children; ALLERGY in children; INTERLEUKIN-5

• Source: Lancet. 1/8/2005, Vol. 365 Issue 9454, p142-149. 8p.

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Treatment of hypereosinophilic syndrome with imatinib mesilate.

• Authors : Gleich, Gerald J; Leiferman, Kristin M; Pardanani, Animesh

Subjects: EOSINOPHIL disorders; DRUG therapy; DRUG efficacy

• Source: Lancet. 5/4/2002, Vol. 359 Issue 9317, p1577. 2p. 1 Chart, 1 Graph.

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Relation of CD4+CD25+ regulatory T-cell suppression of allergendriven T-cell activation to atopic status and expression of allergic disease.

Subjects: T cells; IMMUNOREGULATION; CELL proliferation

• Source: Lancet. 2/21/2004, Vol. 363 Issue 9409, p608-615. 8p.

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Agricola

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Agricola

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L-tryptophan contaminant "peak E" and interleukin-5 production from T cells.

• Authors : Yamaoka, K A (AUTHOR); Miyasaka, N (AUTHOR); Kashiwazaki, S (AUTHOR)

• Source: Lancet. 12/7/1991, Vol. 338 Issue 8780, p1468-1468. 1p.

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Targeting cytokines in asthma therapy: round one.

• Authors : Boushey, Homer A; Fahy, John V

Subjects: ASTHMA treatment; INTERLEUKINS; CYTOKINES

• Source: Lancet. 12/23/2000, Vol. 356 Issue 9248, p2114. 3p. 1 Diagram.

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