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Academic Journal

Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria.

  • Authors : Rahn HP; Department of Chemistry, Stanford University, Stanford, California 94305, United States.; Liu X

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemistry ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemical synthesis

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2024 Aug 14; Vol. 146 (32), pp. 22541-22552. Date of Electronic Publication: 2024 Aug 01.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB.

  • Authors : Nguy AKL; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.; Martinie RJ

Subjects: Vancomycin*/Vancomycin*/Vancomycin*/chemistry ; Vancomycin*/Vancomycin*/Vancomycin*/biosynthesis; Kinetics

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2024 Jul 24; Vol. 146 (29), pp. 19629-19634. Date of Electronic Publication: 2024 Jul 11.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach.

  • Authors : Lei E; Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, and School of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China.; Tao H

Subjects: Gram-Negative Bacteria* ; Vancomycin*/Vancomycin*/Vancomycin*/pharmacology; Animals

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2022 Jun 15; Vol. 144 (23), pp. 10622-10639. Date of Electronic Publication: 2022 Jun 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Multicopper Clusters Enable Oxidative Phenol Macrocyclization (OxPM) of Peptides.

  • Authors : Libman A; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.; Ben-Lulu M

Subjects: Vancomycin*/Vancomycin*/Vancomycin*/chemistry ; Phenol*; Peptides/Peptides/Peptides/chemistry

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2023 Sep 27; Vol. 145 (38), pp. 21002-21011. Date of Electronic Publication: 2023 Sep 18.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Divergent Total Synthesis and Characterization of Maxamycins.

Subjects: Vancomycin* ; Anti-Bacterial Agents*; Staphylococcus aureus/Staphylococcus aureus/Staphylococcus aureus/metabolism

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2023 Jun 14; Vol. 145 (23), pp. 12837-12852. Date of Electronic Publication: 2023 Jun 06.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Next-Generation Total Synthesis of Vancomycin.

  • Authors : Moore MJ; Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.; Qu S

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*chemical synthesis ; Vancomycin/Vancomycin/Vancomycin/*chemical synthesis; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/chemistry

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2020 Sep 16; Vol. 142 (37), pp. 16039-16050. Date of Electronic Publication: 2020 Sep 04.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics.

  • Authors : Okano A; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.; Nakayama A

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*chemical synthesis ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Biphenyl Compounds/Biphenyl Compounds/Biphenyl Compounds/*chemistry

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2015 Mar 18; Vol. 137 (10), pp. 3693-704. Date of Electronic Publication: 2015 Mar 09.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

  • Authors : Okano A; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.; Nakayama A

Subjects: Alanine/Alanine/Alanine/*analogs & derivatives ; Dipeptides/Dipeptides/Dipeptides/*chemistry ; Lactates/Lactates/Lactates/*chemistry

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2014 Oct 01; Vol. 136 (39), pp. 13522-5. Date of Electronic Publication: 2014 Sep 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands.

  • Authors : Okano A; Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.; James RC

Subjects: Amidines/Amidines/Amidines/*chemistry ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*chemical synthesis ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*metabolism

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2012 May 30; Vol. 134 (21), pp. 8790-3. Date of Electronic Publication: 2012 May 17.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria.

  • Authors : Xie J; Department of Chemistry, The Skaggs Institute for Chemical Biology, La Jolla, California 92037, United States.; Pierce JG

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*chemistry ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*metabolism ; Dipeptides/Dipeptides/Dipeptides/*metabolism

  • Source: Journal of the American Chemical Society [J Am Chem Soc] 2011 Sep 07; Vol. 133 (35), pp. 13946-9. Date of Electronic Publication: 2011 Aug 16.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  265 results for ""Vancomycin""